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血液透析患者便秘情况及其相关因素分析 被引量:13
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作者 吴禹池 张上鹏 +2 位作者 尹自长 邹川 林启展 《中国现代医学杂志》 CAS 2018年第12期58-62,共5页
目的对慢性肾脏病(CKD)维持血液透析(HD)患者便秘的发生情况及其相关因素进行调查。方法根据RomeⅢ诊断标准制作调查表,选取2016年3月该院行HD患者进行问卷调查,了解其便秘的发生情况,并探讨其相关因素。结果共调查206例HD患者,193例应... 目的对慢性肾脏病(CKD)维持血液透析(HD)患者便秘的发生情况及其相关因素进行调查。方法根据RomeⅢ诊断标准制作调查表,选取2016年3月该院行HD患者进行问卷调查,了解其便秘的发生情况,并探讨其相关因素。结果共调查206例HD患者,193例应答,应答率为93.7%;便秘发生率为34.2%。单因素分析结果显示,HD充分性(Kt/V)、血清硫酸吲哚酚(IS)水平、每日蔬菜摄入量、进食蔬菜、水果及运动习惯与HD患者便秘相关。逐步多因素Logistic回归分析提示,IS水平[OR=1.051(95%CI:1.009,1.095)]和Kt/V[OR=0.264(95%CI:0.074,0.945)]是HD患者发生便秘的主要影响因素。结论 HD患者有较高的便秘发生率。IS蓄积是HD患者发生便秘的危险因素,而较高的Kt/V则是保护因素。 展开更多
关键词 慢性肾脏病 血液透析 便秘 硫酸吲哚酚 横断面调查
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Old Drug for New Use: Searching for MEK1 (Mitogen- Activated Protein Kinase Kinase 1) Inhibitor by the Computer Aided Drug Design
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作者 Po-Yuan Chen Hong-Jye Hong +5 位作者 Mien-De Jhuo Tzu-Ching Shih yu-chi wu Chia-Hsing Cheng Yen-YuHuang Tzu-Hurng Cheng 《Journal of Life Sciences》 2013年第5期453-458,共6页
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Optimized online filter stack spectrometer for ultrashort X-ray pulses
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作者 Jia-Xing Wen Ge Ma +17 位作者 Ming-Hai Yu yu-chi wu Yong-Hong Yan Shao-Yi Wang Huai-Zhong Gao Lu-Shan Wang Yu-Gang Zhou Qiang Li Yue Yang Fang Tan Xiao-Hui Zhang Jie Zhang Wen-Bo Mo Jing-Qin Su Wei-Min Zhou Yu-Qiu Gu Ming Zeng Zong-Qing Zhao 《Nuclear Science and Techniques》 SCIE EI CAS 2024年第5期85-98,共14页
Currently,with the advent of high-repetition-rate laser-plasma experiments,the demand for online diagnosis for the X-ray spectrum is increasing because the laser-plasma-generated X-ray spectrum is very important for c... Currently,with the advent of high-repetition-rate laser-plasma experiments,the demand for online diagnosis for the X-ray spectrum is increasing because the laser-plasma-generated X-ray spectrum is very important for characterizing electron dynamics and applications.In this study,scintillators and silicon PIN(P-type–intrinsic-N-type semiconductor)diodes were used to construct a wideband online filter stack spectrometer.The X-ray sensor and filter arrangement was optimized using a genetic algorithm to minimize the condition number of the response matrix.Consequently,the unfolding error was significantly reduced based on numerical experiments.The detector responses were quantitatively calibrated by irradiating the scintillator and PIN diode with various nuclides and comparing the measuredγ-ray peaks.A prototype 15-channel spectrometer was developed by integrating an X-ray detector with front-and back-end electronics.The prototype spectrometer could record X-ray pulse signals at a repetition rate of 1 kHz.Furthermore,an optimized spectrometer was employed to record the real-time spectra of laser-driven bremsstrahlung sources.This optimized spectrometer offers a compact solution for spectrum diagnostics of ultrashort X-ray pulses,exhibiting improved accuracy in terms of spectrum measurements and repetition rates,and could be widely used in next-generation high-repetition-rate high-power laser facilities. 展开更多
关键词 Filter stack spectrometer Laser plasma diagnostics X-ray diagnostics Scintillator PIN diode
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Hard x-ray transmission curved crystal spectrometers(10–100 keV) for laser fusion experiments at the ShenGuang-Ⅲ laser facility 被引量:1
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作者 Ming-hai Yu Guang-yue Hu +6 位作者 Ning An Feng Qian yu-chi wu Xiao-ding Zhang Yu-qiu Gu Qiu-ping Wang Jian Zheng 《High Power Laser Science and Engineering》 SCIE CAS CSCD 2016年第1期9-16,共8页
Two transmission curved crystal spectrometers are designed to measure the hard x-ray emission in the laser fusion experiment of Compton radiography of implosion target on ShenGuang-III laser facility in China. Cylindr... Two transmission curved crystal spectrometers are designed to measure the hard x-ray emission in the laser fusion experiment of Compton radiography of implosion target on ShenGuang-III laser facility in China. Cylindrically curvedα-quartz(10–11) crystals with curvature radii of 150 and 300 mm are used to cover spectral ranges of 10–56 and17–100 ke V, respectively. The distance between the crystal and the x-ray source can be changed over a broad distance from 200 to 1500 mm. The optical design, including the integral reflectivity of the curved crystal, the sensitivity, and the spectral resolution of the spectrometers, is discussed. We also provide mechanic design details and experimental results using a Mo anode x-ray source. High-quality spectra were obtained. We confirmed that the spectral resolution can be improved by increasing the working distance, which is the distance between the recording medium and the Rowland circle. 展开更多
关键词 curved CRYSTAL SPECTROMETER HARD X-RAY laser fusion
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