Graphene and graphene-based materials have the ability to induce stem cells to differentiate into neurons,which is necessary to overcome the current problems faced in the clinical treatment of spinal cord injury.This ...Graphene and graphene-based materials have the ability to induce stem cells to differentiate into neurons,which is necessary to overcome the current problems faced in the clinical treatment of spinal cord injury.This review summarizes the advantages of graphene and graphene-based materials(in particular,composite materials)in axonal repair after spinal cord injury.These materials have good histocompatibility,and mechanical and adsorption properties that can be targeted to improve the environment of axonal regeneration.They also have good conductivity,which allows them to make full use of electrical nerve signal stimulation in spinal cord tissue to promote axonal regeneration.Furthermore,they can be used as carriers of seed cells,trophic factors,and drugs in nerve tissue engineering scaffolds to provide a basis for constructing a local microenvironment after spinal cord injury.However,to achieve clinical adoption of graphene and graphene-based materials for the repair of spinal cord injury,further research is needed to reduce their toxicity.展开更多
Annealing temperatures and applied magnetic fields are two important parameters for the performance modification of magnetic alloys.This article investigated the effect of different annealing temperatures on crystalli...Annealing temperatures and applied magnetic fields are two important parameters for the performance modification of magnetic alloys.This article investigated the effect of different annealing temperatures on crystallization condition,magnetic properties and thermal stability of the amorphous magnetic alloy Co_(36)Fe_(36)Si_(4.8)B1_(9.2)Nb_(4)(at%).Results indicate that the annealing temperature can significantly affect the size and content of precipitated nanocrystals in the amorphous alloy,and the precipitation of nanocrystalline phases can result in the distinct change of magnetic properties and Curie temperature.When the annealing was performed at 595 ℃ for 30 min under an applied transverse external magnetic field of 9550.0A·m^(-1),the amorphous alloy shows excellent soft magnetic properties with the saturation magnetization of alloy reaching 110.00 mA·m^(2)·g^(-1),the residual magnetic induction intensity of 4 × 10^(-6) T and the coercivity as low as57.3 A·m^(-1).Furthermore,the Curie temperature of the field-annealed samples can reach up to 440 0C,approximately 58℃ higher than that of the as-quenched species.展开更多
Since the outbreak of novel coronavirus pneumonia(coronavirus disease 2019,COVID-19),it has rapidly spread to 187 countries,causing serious harm to the health of people and a huge social burden.However,currently,drugs...Since the outbreak of novel coronavirus pneumonia(coronavirus disease 2019,COVID-19),it has rapidly spread to 187 countries,causing serious harm to the health of people and a huge social burden.However,currently,drugs specifically approved for clinical use are not available,except for vaccines against COVID-19 that are being evaluated.Traditional Chinese medicine(TCM)is capable of performing syndrome differentiation and treatment according to the clinical manifestations of patients,and has a better ability of epidemic prevention and control.The authors comprehensively analyzed the etiology and pathogenesis of COVID-19 based on the theory of TCM,and discussed its syndrome differentiation,treatment and prevention measures so as to provide strategies and reference for the prevention and treatment with TCM.展开更多
基金supported by the Lanzhou Talent Innovation and Entrepreneurship Project,No.2020-RC-40(to XXW and YBL)Cuiying Scientific Training Program for Undergraduates of Lanzhou University Second Hospital,Nos.CYXZ2020-03,CYXZ2021-01(both to YBL).
文摘Graphene and graphene-based materials have the ability to induce stem cells to differentiate into neurons,which is necessary to overcome the current problems faced in the clinical treatment of spinal cord injury.This review summarizes the advantages of graphene and graphene-based materials(in particular,composite materials)in axonal repair after spinal cord injury.These materials have good histocompatibility,and mechanical and adsorption properties that can be targeted to improve the environment of axonal regeneration.They also have good conductivity,which allows them to make full use of electrical nerve signal stimulation in spinal cord tissue to promote axonal regeneration.Furthermore,they can be used as carriers of seed cells,trophic factors,and drugs in nerve tissue engineering scaffolds to provide a basis for constructing a local microenvironment after spinal cord injury.However,to achieve clinical adoption of graphene and graphene-based materials for the repair of spinal cord injury,further research is needed to reduce their toxicity.
基金financially supported by National S&T Major Project of China (No.2018ZX10301201)the National Natural Science Foundation of China (No.51371018)the Fundamental Research Funds for the Central Universities (No. FRF-BR-14-001B)。
文摘Annealing temperatures and applied magnetic fields are two important parameters for the performance modification of magnetic alloys.This article investigated the effect of different annealing temperatures on crystallization condition,magnetic properties and thermal stability of the amorphous magnetic alloy Co_(36)Fe_(36)Si_(4.8)B1_(9.2)Nb_(4)(at%).Results indicate that the annealing temperature can significantly affect the size and content of precipitated nanocrystals in the amorphous alloy,and the precipitation of nanocrystalline phases can result in the distinct change of magnetic properties and Curie temperature.When the annealing was performed at 595 ℃ for 30 min under an applied transverse external magnetic field of 9550.0A·m^(-1),the amorphous alloy shows excellent soft magnetic properties with the saturation magnetization of alloy reaching 110.00 mA·m^(2)·g^(-1),the residual magnetic induction intensity of 4 × 10^(-6) T and the coercivity as low as57.3 A·m^(-1).Furthermore,the Curie temperature of the field-annealed samples can reach up to 440 0C,approximately 58℃ higher than that of the as-quenched species.
文摘Since the outbreak of novel coronavirus pneumonia(coronavirus disease 2019,COVID-19),it has rapidly spread to 187 countries,causing serious harm to the health of people and a huge social burden.However,currently,drugs specifically approved for clinical use are not available,except for vaccines against COVID-19 that are being evaluated.Traditional Chinese medicine(TCM)is capable of performing syndrome differentiation and treatment according to the clinical manifestations of patients,and has a better ability of epidemic prevention and control.The authors comprehensively analyzed the etiology and pathogenesis of COVID-19 based on the theory of TCM,and discussed its syndrome differentiation,treatment and prevention measures so as to provide strategies and reference for the prevention and treatment with TCM.