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Velocity distribution of flow with submerged flexible vegetations based on mixing-length approach 被引量:2
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作者 槐文信 韩杰 +3 位作者 曾玉红 安翔 钱忠东 yu-lu liu 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2009年第3期343-351,共9页
By choosing a PVC slice to simulate flexible vegetation, we carried out experiments in an open channel with submerged flexible vegetation. A 3D acoustic Doppler velocimeter (micro ADV) was used to measure local flow... By choosing a PVC slice to simulate flexible vegetation, we carried out experiments in an open channel with submerged flexible vegetation. A 3D acoustic Doppler velocimeter (micro ADV) was used to measure local flow velocities and Reynolds stress. The results show that hydraulic characteristics in non-vegetation and vegetation layers are totally different. In a region above the vegetation, Reynolds stress distribution is linear, and the measured velocity profile is a classical logarithmic one. Based on the concept of new-riverbed, the river compression parameter representing the impact of vegetation on river is given, and a new assumption of mixing length expression is made. The formula for time-averaged velocity derived from the expression requires less parameters and simple calculation, and is useful in applications. 展开更多
关键词 flexible vegetation PVC slice micro ADV mixing-length approach streamwise velocity distribution Reynolds stress river compression parameter
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补体激活与自噬在年龄相关性黄斑变性中的研究进展 被引量:3
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作者 刘雨露 徐新荣 《国际眼科杂志》 CAS 北大核心 2020年第6期995-998,共4页
年龄相关性黄斑变性(age-related macular degeneration,ARMD)是一种随年龄增长而发病率逐渐上升的黄斑部疾病,目前认为其发病因素与患者的年龄、遗传、吸烟、氧化应激、免疫炎症反应、RPE细胞老化和代谢异常等有关。补体系统在机体防... 年龄相关性黄斑变性(age-related macular degeneration,ARMD)是一种随年龄增长而发病率逐渐上升的黄斑部疾病,目前认为其发病因素与患者的年龄、遗传、吸烟、氧化应激、免疫炎症反应、RPE细胞老化和代谢异常等有关。补体系统在机体防御感染、免疫调节和炎症应答中扮演重要角色,补体系统异常激活引起免疫炎症近年来被认为是ARMD发病的重要原因。而自噬过程也参与了ARMD的发病。正常的自噬是细胞自我保护以及维持稳态的一个重要途径,当自噬被阻断时,可加剧氧化应激损伤,导致ARMD的发展。补体激活与自噬过程的均衡调节是控制ARMD发展的重要手段。 展开更多
关键词 年龄相关性黄斑变性 补体激活 自噬过程
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Numerical investigation on compressible flow around a cylinder in proximity to the heated wall
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作者 yu-lu liu Jun-wang Qu +2 位作者 Yi-zhou Tao Yong-guang Lyu Xiang Qiu 《Journal of Hydrodynamics》 SCIE EI CSCD 2024年第3期519-533,共15页
In this study,direct numerical simulations were conducted to investigate the compressible flow around a circular cylinder near a heated wall at a Reynolds number(Re)of 500 and a Mach number(Ma)of 0.4.The heating ratio... In this study,direct numerical simulations were conducted to investigate the compressible flow around a circular cylinder near a heated wall at a Reynolds number(Re)of 500 and a Mach number(Ma)of 0.4.The heating ratio T^(*)ranging from 1.0 to 1.6 represents the different situations of a heated wall,whereas the gap ratio ranges from 0.3 to 1.0.This study analyzed the impact of heating effect and wall proximity on flow characteristics and aerodynamic forces.The results indicated that the stability of the flow was enhanced as the gap ratio decreased or the heating ratio increased.Through the calculation of enstrophy,it was found that the strength of shedding vortices weakens with a decrease in gap ratio or an increase in heating ratio.Furthermore,the mean drag coefficient decreases as the heating ratio increases or the gap ratio decreases.In contrast,the mean lift coefficient initially decreases and then increases as the gap ratio decreases.Finally,the drag reduction mechanism was analyzed by examining the pressure distribution on the surface of the cylinder. 展开更多
关键词 Compressible flow wall proximity heating effect stability ENSTROPHY
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Evolution of vortex structure around a wall-mounted rough hemisphere 被引量:1
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作者 Xiang Qiu Hao-xuan liu +2 位作者 Jia-hua Li Yi-zhou Tao yu-lu liu 《Journal of Hydrodynamics》 SCIE EI CSCD 2023年第3期467-481,共15页
In this paper,the large eddy simulation(LES)method is used to calculate Reynolds numbers the range in the range of 3000–30000(based on the diameter of the hemisphere D),and then the statistical analysis method is use... In this paper,the large eddy simulation(LES)method is used to calculate Reynolds numbers the range in the range of 3000–30000(based on the diameter of the hemisphere D),and then the statistical analysis method is used to study the influence of Re on the characteristics of the flow field around the rough hemisphere and the evolution law of the tail vortex.The effect of the Reynolds number on the structure of the rough hemisphere flow field and the evolution of vortex structure is studied by vorticity distribution,POD method,and correlation analysis.It can be observed that with the increase of Reynolds number,the shear in the recirculating region of the rough hemisphere is enhanced,the large-scale structure is reduced,the small-scale structure is increased,and the angle between the hairpin vortex and the wall is reduced.λ_(ci)vortex identification and the Q-criterion are used to capture the evolution of a periodic vortex structure.Q-criterion gives the three-dimensional vortex structure behind the hemispherical flow.It is found that the horseshoe vortex and arch vortex generated by the incoming flow after passing through the hemisphere will interact with the wall surface to form a hairpin vortex,and the hairpin vortex structure will continue to evolve downstream to form a new vortex structure. 展开更多
关键词 Rough hemisphere large eddy simulation(LES) POD method two-point velocity correlation function
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小间隙比下近壁面圆柱绕流尾涡特性研究 被引量:2
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作者 张瑞安 李姜华 +2 位作者 邱翔 刘宇陆 卢志明 《水动力学研究与进展(A辑)》 CSCD 北大核心 2022年第5期657-667,共11页
该文采用DNS方法数值模拟了小间隙比(L/D≤0.5),即圆柱与下壁面距离L和圆柱直径D之间的比值不大于0.5时近壁面单圆柱绕流的流场,并采用瞬时涡度偏差(IVD)和拉格朗日平均涡度偏差(LAVD)方法对涡旋在脱落初期及壁面碰撞阶段的演化进行研... 该文采用DNS方法数值模拟了小间隙比(L/D≤0.5),即圆柱与下壁面距离L和圆柱直径D之间的比值不大于0.5时近壁面单圆柱绕流的流场,并采用瞬时涡度偏差(IVD)和拉格朗日平均涡度偏差(LAVD)方法对涡旋在脱落初期及壁面碰撞阶段的演化进行研究。研究表明,近壁面圆柱绕流脱落涡在初期会存在一段涡旋合并的过程,间隙比小于0.3时,合并发生在脱落涡之间;而间隙比介于0.3和0.5之间时,合并发生于脱落涡和壁面分离涡之间。同时利用从涡旋生成到发展成LAVD涡旋结构(稳定的卡门涡)的时间得到不同间隙比与不同雷诺数下涡旋合并持续的时间,并定量描述了该过程中涡旋内部流体与外部流体的物质交换。该文同时分析了脱落涡与壁面碰撞阶段的能量与动量输运问题,当碰撞发生时,碰撞区域摩擦力方向会发生改变,从而引起近壁涡旋运动特性改变,导致涡旋碰撞前后动能的损失,且其能量损失随间隙比增大而增大,在L/D=0.3、0.4和0.5时碰撞前后动能损失率分别为0.28、0.31和0.36。 展开更多
关键词 近壁面圆柱绕流 脱落涡 拉格朗日拟序结构
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Light therapy:a new option for neurodegenerative diseases 被引量:1
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作者 yu-lu liu Si-Yi Gong +4 位作者 Shu-Ting Xia Ya-Li Wang Hao Peng Yun Shen Chun-Feng liu 《Chinese Medical Journal》 SCIE CAS CSCD 2021年第6期634-645,共12页
Given the increasing incidence of neurodegenerative disease(ND),recent research efforts have intensified the search for curative treatments.Despite significant research,however,existing therapeutic options for ND can ... Given the increasing incidence of neurodegenerative disease(ND),recent research efforts have intensified the search for curative treatments.Despite significant research,however,existing therapeutic options for ND can only slow down the progression of the disease,but not provide a cure.Light therapy(LT)has been used to treat some mental and sleep disorders.This review illustrates recent studies of the use of LT in patients with ND and highlights its potential for clinical applications.The literature was collected from PubMed through June 2020.Selected studies were primarily English articles or articles that could be obtained with English abstracts and Chinese main text.Articles were not limited by type.Additional potential publications were also identified from the bibliographies of identified articles and the authors’reference libraries.The identified literature suggests that LT is a safe and convenient physical method of treatment.It may alleviate sleep disorders,depression,cognitive function,and other clinical symptoms.However,some studies have reported limited or no effects.Therefore,LT represents an attractive therapeutic approach for further investigation in ND.LT is an effective physical form of therapy and a new direction for research into treatments for ND.However,it requires further animal experiments to elucidate mechanisms of action and large,double-blind,randomized,and controlled trials to explore true efficacy in patients with ND. 展开更多
关键词 Neurodegenerative diseases Light therapy Circadian rhythm
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