Rare case of lupus enteritis presenting as colorectum involvement:A case report and review of literature

BACKGROUND Systemic lupus erythematosus(SLE)is a multisystem autoimmune disease that can affect the gastrointestinal tract.Most cases of lupus enteritis(LE)involve the small intestine,while the involvement of the whole colon and rectum without the small intestine being affected is extremely rare.CASE SUMMARY A 35-year-old woman was diagnosed with colorectal LE after initially presenting with intermittent abdominal pain and vomiting for two months.She had a regular medication history for five years following the diagnosis of SLE but had been irregular in taking medications,which may have contributed to the onset of LE and led to her current hospital admission.According to the 2019 Classification criteria for SLE of the European League Against Rheumatism/American College of Rheumatology,this case scored 14.Additionally,abdominal computed tomography revealed significant wall edema of the colon and rectum,ischemia and hyperemia of the ascending colon intestinal wall,mesenteric vessel engorgement,increased mesangial fat attenuation,ascites,and bilateral ureter-hydronephrosis,all indicative of colon and rectum LE.Laboratory tests also showed lower levels of complement C3 and C4,with an antinuclear antibody titer of 1:100.Overall,it was clear that this case involved the colon and rectum without affecting the small intestine,representing a rare manifestation of SLE.The patient received treatment with 10 mg of methylprednisolone sodium succinate,100 mL of 0.9%sodium chloride,hydroxychloroquine(100 mg),and nutrition support.After one week of methylprednisolone and hydroxychloroquine therapy,her SLE symptoms and disease activity improved significantly.CONCLUSION Although colorectal LE without small intestine involvement is very rare,early diagnosis and excellent management with corticosteroids prevented the need for surgical intervention.Physicians should be aware of colorectal LE without small intestine involvement as a manifestation of lupus flare.

Giant enhancement of superconductivity in few layers MoTe2

Recently, the layered transition metal dichalcogenide 1 T MoTe2 has attracted considerable attention due to its non-saturating magnetoresistance, type-Ⅱ Weyl semimetal properties, superconductivity, and potential candidate for twodimensional(2 D) topological insulator in the single-and few-layer limit. Here in this work, we perform systematic transport measurements on thin flakes of MoTe2 prepared by mechanical exfoliation. We find that MoTe2 flakes are superconducting and have an onset superconducting transition temperature Tc up to 5.3 K, which significantly exceeds that of its bulk counterpart. The in-plane upper critical field(Hc2||) is much higher than the Pauli paramagnetic limit, implying that the MoTe2 flakes have Zeeman-protected Ising superconductivity. Furthermore, the Tc and Hc2|| can be tuned by up to 320 mK and 400 mT by applying a gate voltage. Our result indicates that MoTe2 flake is a good candidate for studying exotic superconductivity with nontrivial topological properties.

Multi-carrier transport in ZrTe_5 film

Single-layered zirconium pentatelluride （ZrTes） has been predicted to be a large-gap two-dimensional （2D） topolog- ical insulator, which has attracted particular attention in topological phase transitions and potential device applications. Herein, we investigated the transport properties in ZrTe5 films as a function of thickness, ranging from a few nm to several hundred nm. We determined that the temperature of the resistivity anomaly peak （Tp） tends to increase as the thickness decreases. Moreover, at a critical thickness of ~ 40 rim, the dominating carriers in the films change from n-type to p-type. A comprehensive investigation of Shubnikov-de Hass （SdH） oscillations and Hall resistance at variable temperatures revealed a multi-carrier transport tendency in the thin films. We determined the carrier densities and mobilities of two majority car- riers using the simplified two-carrier model. The electron carriers can be attributed to the Dirac band with a non-trivial Berry phase ~, while the hole carriers may originate from surface chemical reaction or unintentional doping during the microfabrication process. It is necessary to encapsulate the ZrTe5 film in an inert or vacuum environment to potentially achieve a substantial improvement in device quality.

Henan Cultural Information Resources Sharing Project Persistent Effect Mechanism Research

In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance gives certain funds subsidy in the project construction period. Embarks highly from strategy during construction plan chosen and operational system management, as while as union digital library to construct a persistent effect mechanism. With the principle of state guidance, enterprise operation and benefit farmers, expand culture industry within the provincial and safeguard Cultural Information Resources Sharing Project sustainable development's, then promotes the rural economy culture full scale development.

消费者对不同购买诱因心理和行为反应的实证研究——以大学生群体为例

购买诱因包括慈善购买诱因和金钱购买诱因,二者都作为重要的促销手段被广泛使用。随着消费者认知水平的增强和对企业社会责任要求的提高,比起传统的金钱购买诱因,慈善购买诱因成为新的消费增长点。本研究对象限定为学生群体,用实证分析方法探索他们在选择低价消费品时会受到以上促销手段怎样的影响,对不同促销手段的认知、情感、行为反应。我们引入了心理学中"热情—能力"感知的概念,来分析消费者感知的差异以及对产品的态度和购买意愿。同时,我们还将消费者按照自我建构水准划分为自我型和依存型,并探索消费者本身属性的变化是否影响他们对购买诱因的感知。研究结果显示,比起提供金钱购买诱因的企业,消费者对提供慈善购买诱因的企业更加有热情的认知。这种认知,又因消费者本身的自我建构水准而变化,依存型自我建构人群对慈善购买诱因持有更加肯定的认知。

社交媒体旅游分享信息对冲动性旅游意愿的影响研究

Web3.0时代下社交媒体盛行,人们利用社交媒体记录并分享生活已经成为新时尚。随着经济日趋回暖,消费者的旅游需求得到极大激发,特别是社交媒体的信息给消费者带来临场感的体验,说走就走的旅行成为一种潮流。考虑到临场感在虚拟媒介环境中的普遍性,文章从这一角度出发,探索社会化媒介中旅游分享信息对冲动性旅游意愿的影响。研究结果表明,用户的共存临场感、交流临场感和情感临场感,在不同程度上会影响唤起与心流体验,从而促使消费者产生旅游冲动。在数字时代,文章能够为互联网旅游策划提供理论和实践参考。

基于多视角卷积神经网络的三维模型分类方法

近些年来,卷积神经网络框架在二维图像的语义分割、分类、检索等领域取得了非常好的效果.但是由于三维模型结构的复杂性与不规律性,卷积神经网络的卷积和池化操作却无法直接应用在三维模型上.为了发挥深度学习框架在二维图像分析领域积累的技术优势,本文采用基于多视角投影的方法来完成三维模型分类的任务.然而现有的基于多视角投影的三维模型分类方法大多采用固定视角,所采集到的多视角下模型投影渲染图中存在大量的信息冗余,对结果造成一定的干扰.本文提出了一种新型的多视角卷积神经网络框架,在网络训练过程中自动判别每个视角的贡献度,舍弃冗余视角的信息,从而提取出最能表征模型类别的特征,提高了网络的鲁棒性.此外,本文将基于视点熵的最佳视角选择方法引入三维模型分类领域,相比于固定视角方法,本文方法能更多地保留模型的细节信息,同时不需要模型的朝向对齐.通过在ModelNet10和ModelNet40数据集上的实验,验证了将基于视点熵的视角选择方法应用于三维模型分类,以及本文提出的基于视角判别的多视角信息融合方法的合理性和优越性.实验结果表明,本文方法的分类准确性也优于现有的基于固定多视角投影的三维模型分类方法.

Control on the Morphology of ABA Amphiphilic Triblock Copolymer Micelles in Dioxane/Water Mixture Solvent

This work offers a typical understanding of the factors that govern the nanostructures of poly（4-vinyl pyridine）-b-polystyrene-bpoly（4-vinyl pyridine）（P4 VP-b-PS-b-P4 VP） block copolymers（BCs） in dioxane/water, in which water is a selective solvent for the P4 VP block. It is achieved through an investigation of the amphiphilic triblock copolymer micelles by variation of three different factors, including water content（above CWC but under the immobile concentration）, temperature（ranging from 20 °C to 80 °C）, and copolymer composition（low and high PS block length）. Transition of bead-like micelles to vesicles is observed with the increase of water content due to the increase of interfacial energy between the copolymer and the solvent. Effect of temperature superposed on that of water content results in various morphologies, such as beads, fibers, rods, capsules, toroids, lamellae, and vesicles. The interfacial tension between the BC and the solvent increases with the increase of water content but decreases with the increase of temperature, indicating that the micellar morphologies are resulted from the competitive interplay between the temperature and the water content and always change in a direction that decreases the interfacial energy. Based on the micellar structures obtained in this work and the effects of temperature superposed on water concentration, a diagram of phase evolution of different micellar morphologies is illustrated here, covering the temperature range from 20 °C to 80 °C and the water content changing from 20 vol% to 35 vol%. For the investigation of BC composition, morphological transition of vesicle-to-fiber, for high PS length, is observed as compared with bead-to-capsule for low PS length, as the temperature changes from 20 °C to 80 °C. Our research complements the protocols to control over the morphologies and the phase diagram describing P4 VP-b-PS-b-P4 VP micellar nanostructures in aqueous solution.

Bandgap opening in MoTe2 thin flakes induced by surface oxidation

Recently,the layered transition metal dichalcogenide 1T′-MoTe2 has generated considerable interest due to their superconducting and non-trivial topological properties.Here,we present a systematic study on 1T′-MoTe2 single-crystal and exfoliated thin-flakes by means of electrical transport,scanning tunnelling microscope(STM)measurements and band structure calculations.For a bulk sample,it exhibits large magneto-resistance(MR)and Shubnikov–de Hass oscillations inρxx and a series of Hall plateaus inρxy at low temperatures.Meanwhile,the MoTe2 thin films were intensively investigated with thickness dependence.For samples,without encapsulation,an apparent transition from the intrinsic metallic to insulating state is observed by reducing thickness.In such thin films,we also observed a suppression of the MR and weak anti-localization(WAL)effects.We attributed these effects to disorders originated from the extrinsic surface chemical reaction,which is consistent with the density functional theory(DFT)calculations and in-situ STM results.In contrast to samples without encapsulated protection,we discovered an interesting superconducting transition for those samples with hexagonal Boron Nitride(h-BN)film protection.Our results indicate that the metallic or superconducting behavior is its intrinsic state,and the insulating behavior is likely caused by surface oxidation in few layer 1T’-MoTe2 flakes.

Establishment of a model of Mycoplasma hyopneumoniae infection using Bama miniature pigs

Mycoplasma hyopneumoniae(M.hyopneumoniae),is the primary aetiological agent of enzootic pneumonia leading to chronic respiratory disease prevalent worldwide.Conventional pigs are the only animals used for pathogenicity studies and vaccine evaluations of M.hyopneumoniae.Considering that the challenge animals have better genetic stability and a smaller body size to operate with,an alternative experimental animal model of M.hyopneumoniae infection with Bama miniature pigs was established.Nine seven-week-old snatch-farrowed,porcine colostrum-deprived(SF-pCD)Bama miniature pigs and nine conventional pigs were randomly divided into two infected groups(Bama miniatureinfected(BI)and conventional-infected groups(CI),BI and CI,n=6)and two control groups(Bama miniature control(BC)and conventional control(CC)groups,BC and CC,n=3).Every piglet was tracheally inoculated with 5×10^(8) CCU/mL containing 10%suspension of a stock of frozen lung homogenate from SF-pCD pigs infected with virulent strain JS or sterilized KM2 medium.Typical lung lesions appeared in all infected pigs after necropsy,and the mean gross lung lesions was 17.3 and 13.7 in groups of BI and CI.Serum IgG and nasal sIgA antibody titres were increased significantly.Cilia shedding and mucus staining increased greatly in JS-infected bronchi.Obvious reddish gross lesions and M.hyopneumoniae antigen were detected,especially apparently observed in group of BI.Moreover,DNA copies of M.hyopneumoniae from bronchoalveolar lavage fluid(BALF)of each JS-infected piglet reached more than 10^(8),and M.hyopneumoniae could be re-isolated from each infected BALF.These results indicate that Bama miniature pigs could be used as an alternative and more maneuverable experimental infection model for M.hyopneumoniae and display typical clinical and pathological features consistent with those in conventional pigs.