Objective: To explore the clinical significance of serum S100B in chronic heart failure (CHF). Methods: A total of 300 patients with CHF of cardiac function levels II–IV were divided into three groups, and 300 normal...Objective: To explore the clinical significance of serum S100B in chronic heart failure (CHF). Methods: A total of 300 patients with CHF of cardiac function levels II–IV were divided into three groups, and 300 normal cases were selected as controls. Serum S100B, B-type natriuretic peptide (BNP), LVEF(%) and LVEDD were detected and analyzed. CHF patients were followed up for 1 year. Statistical analysis was performed using SPSS and Microsoft Excel. Results: The level of S100B in CHF patients was significantly increased, and the serum level was positively correlated with BNP. The serum S100B level was positively correlated with heart failure classification, and the area under ROC curve was 0.84. The sensitivity and specificity were 81.2% and 71.5%, respectively. Patients with high serum S100B were at higher risk of major cardiovascular events. Conclusion: Serum S100B level is significantly increased in patients with chronic heart failure, and is negatively correlated with the patients' cardiac function. It is an independent risk factor for the occurrence and development of chronic heart failure, and it has implications for the prognosis of patients with chronic heart failure.展开更多
Mechanical properties of weld metal are the key factors affecting the quality of heavy-wall X80 hot induction bends. The effects of bending parameters on the mechanical properties of weld metal for hot bends were inve...Mechanical properties of weld metal are the key factors affecting the quality of heavy-wall X80 hot induction bends. The effects of bending parameters on the mechanical properties of weld metal for hot bends were investigated by simulation conducted on a Gleeble 3500 thermal simulator. Continuous cooling transformation （CCT） dia- grams of the weld metal were also constructed. The influences of hot bending parameters （such as reheating temperature, cooling rate, and tempering temperature） on the microstructure and mechanical properties of weld metal were also analyzed. Results show that the strength of all weld metal specimens is higher than the value indicated in the technical specification and increases with the increase of reheating temperature, cooling rate, and tempering tempera ture. The impact toughness is apparently related to the variation of reheating temperature, cooling rate, and tempering temperature.展开更多
基金Hainan Natural Science Foundation Project.Project No:817336.
文摘Objective: To explore the clinical significance of serum S100B in chronic heart failure (CHF). Methods: A total of 300 patients with CHF of cardiac function levels II–IV were divided into three groups, and 300 normal cases were selected as controls. Serum S100B, B-type natriuretic peptide (BNP), LVEF(%) and LVEDD were detected and analyzed. CHF patients were followed up for 1 year. Statistical analysis was performed using SPSS and Microsoft Excel. Results: The level of S100B in CHF patients was significantly increased, and the serum level was positively correlated with BNP. The serum S100B level was positively correlated with heart failure classification, and the area under ROC curve was 0.84. The sensitivity and specificity were 81.2% and 71.5%, respectively. Patients with high serum S100B were at higher risk of major cardiovascular events. Conclusion: Serum S100B level is significantly increased in patients with chronic heart failure, and is negatively correlated with the patients' cardiac function. It is an independent risk factor for the occurrence and development of chronic heart failure, and it has implications for the prognosis of patients with chronic heart failure.
基金Sponsored by National Natural Science Foundation of China(51171162)R & D Project of CITIC-CBMM(2011-D056-3)
文摘Mechanical properties of weld metal are the key factors affecting the quality of heavy-wall X80 hot induction bends. The effects of bending parameters on the mechanical properties of weld metal for hot bends were investigated by simulation conducted on a Gleeble 3500 thermal simulator. Continuous cooling transformation （CCT） dia- grams of the weld metal were also constructed. The influences of hot bending parameters （such as reheating temperature, cooling rate, and tempering temperature） on the microstructure and mechanical properties of weld metal were also analyzed. Results show that the strength of all weld metal specimens is higher than the value indicated in the technical specification and increases with the increase of reheating temperature, cooling rate, and tempering tempera ture. The impact toughness is apparently related to the variation of reheating temperature, cooling rate, and tempering temperature.
