This paper describes the investigation of the secretion of extracellular polymeric substances(EPS)by an extremely thermoacidophilic archaea,Metallosphaera sedula(M.sedula),during the bioleaching of pyrite under differ...This paper describes the investigation of the secretion of extracellular polymeric substances(EPS)by an extremely thermoacidophilic archaea,Metallosphaera sedula(M.sedula),during the bioleaching of pyrite under different temperatures and discusses the relationship among the EPS secretion,its heat resistance,and its ability to bioleach pyrite.The investigation results indicate that the amount of extracellular proteins is significantly higher than the amount of extracellular polysaccharides in the extracted EPS whether free cells or attached cells;these results are quite different from the behavior of mesophilic Acidithiobacillus ferrooxidans.Although the growth of M.sedula is inhibited at 80℃,the bioleaching ability of M.sedula is only slightly lower than that at the optimum growth temperature of 72℃ because of the heat resistance mechanism based on EPS secretion.The secretion of more extracellular proteins is an important heat resistance mechanism of M.sedula.展开更多
General purpose graphics processing units(GPGPUs)can be used to improve computing performance considerably for regular applications.However,irregular memory access exists in many applications,and the benefits of graph...General purpose graphics processing units(GPGPUs)can be used to improve computing performance considerably for regular applications.However,irregular memory access exists in many applications,and the benefits of graphics processing units(GPUs)are less substantial for irregular applications.In recent years,several studies have presented some solutions to remove static irregular memory access.However,eliminating dynamic irregular memory access with software remains a serious challenge.A pure software solution without hardware extensions or offline profiling is proposed to eliminate dynamic irregular memory access,especially for indirect memory access.Data reordering and index redirection are suggested to reduce the number of memory transactions,thereby improving the performance of GPU kernels.To improve the efficiency of data reordering,an operation to reorder data is offloaded to a GPU to reduce overhead and thus transfer data.Through concurrently executing the compute unified device architecture(CUDA)streams of data reordering and the data processing kernel,the overhead of data reordering can be reduced.After these optimizations,the volume of memory transactions can be reduced by 16.7%-50%compared with CUSPARSE-based benchmarks,and the performance of irregular kernels can be improved by 9.64%-34.9%using an NVIDIA Tesla P4 GPU.展开更多
基金supported by the National Natural Science Foundation of China(22022402,21974051 for L.Zhang and 22004037,21635003,21827814,and 21811540027 for Y.Tian)the Innovation Program of Shanghai Municipal Education Commission(201701070005E00020)for Y.Tian.
基金financially supported by the National Natural Science Foundation of China (Nos. 31470230, 51320105006, 51604308, and 31100173)the Youth Talent Foundation of Hunan Province of China (No. 2017RS3003)the National Science Foundation of Hunan Province of China (No. 2018JJ2486)
文摘This paper describes the investigation of the secretion of extracellular polymeric substances(EPS)by an extremely thermoacidophilic archaea,Metallosphaera sedula(M.sedula),during the bioleaching of pyrite under different temperatures and discusses the relationship among the EPS secretion,its heat resistance,and its ability to bioleach pyrite.The investigation results indicate that the amount of extracellular proteins is significantly higher than the amount of extracellular polysaccharides in the extracted EPS whether free cells or attached cells;these results are quite different from the behavior of mesophilic Acidithiobacillus ferrooxidans.Although the growth of M.sedula is inhibited at 80℃,the bioleaching ability of M.sedula is only slightly lower than that at the optimum growth temperature of 72℃ because of the heat resistance mechanism based on EPS secretion.The secretion of more extracellular proteins is an important heat resistance mechanism of M.sedula.
基金Project supported by the National Key Research and Development Program of China(No.2018YFB1003500)。
文摘General purpose graphics processing units(GPGPUs)can be used to improve computing performance considerably for regular applications.However,irregular memory access exists in many applications,and the benefits of graphics processing units(GPUs)are less substantial for irregular applications.In recent years,several studies have presented some solutions to remove static irregular memory access.However,eliminating dynamic irregular memory access with software remains a serious challenge.A pure software solution without hardware extensions or offline profiling is proposed to eliminate dynamic irregular memory access,especially for indirect memory access.Data reordering and index redirection are suggested to reduce the number of memory transactions,thereby improving the performance of GPU kernels.To improve the efficiency of data reordering,an operation to reorder data is offloaded to a GPU to reduce overhead and thus transfer data.Through concurrently executing the compute unified device architecture(CUDA)streams of data reordering and the data processing kernel,the overhead of data reordering can be reduced.After these optimizations,the volume of memory transactions can be reduced by 16.7%-50%compared with CUSPARSE-based benchmarks,and the performance of irregular kernels can be improved by 9.64%-34.9%using an NVIDIA Tesla P4 GPU.
