A novel synthesis of spirocyclopropylpyrazole derivatives tethered with a trifluoromethyl unit through an unprecedented cascade reaction of alkylidenecyclopropanes with pyrazolidinones and trifluoroethanol(TFE)has bee...A novel synthesis of spirocyclopropylpyrazole derivatives tethered with a trifluoromethyl unit through an unprecedented cascade reaction of alkylidenecyclopropanes with pyrazolidinones and trifluoroethanol(TFE)has been developed.展开更多
基金We are grateful to the National Natural Science Foundation of China(U2004189)the Central Plains Science and Technology Innovation Leader Project(224200510009)+3 种基金the Program for Innovative Research Team in Science and Technology in Universities of Henan Province(20IRTSTHN005)the Natural Science Foundation of Henan Province(212300410364)the Henan Key Laboratory of Organic Functional Molecules and Drug Innovationthe 111 Project(D17007)for financial support.
文摘A novel synthesis of spirocyclopropylpyrazole derivatives tethered with a trifluoromethyl unit through an unprecedented cascade reaction of alkylidenecyclopropanes with pyrazolidinones and trifluoroethanol(TFE)has been developed.