Linear polarization holography

Polarization holography is a newly researched field,that has gained traction with the development of tensor theory.It primarily focuses on the interaction between polarization waves and photosensitive materials.The extraordinary capabil-ities in modulating the amplitude,phase,and polarization of light have resulted in several new applications,such as holo-graphic storage technology,multichannel polarization multiplexing,vector beams,and optical functional devices.In this paper,fundamental research on polarization holography with linear polarized wave,a component of the theory of polariz-ation holography,has been reviewed.Primarily,the effect of various polarization changes on the linear and nonlinear po-larization characteristics of reconstructed wave under continuous exposure and during holographic recording and recon-struction have been focused upon.The polarization modulation realized using these polarization characteristics exhibits unusual functionalities,rendering polarization holography as an attractive research topic in many fields of applications.This paper aims to provide readers with new insights and broaden the application of polarization holography in more sci-entific and technological research fields.

Collinear holographic data storage technologies

In the era of information explosion,the demand of data storage is increased dramatically.Holographic data storage technology is one of the most promising next-generation data storage technologies due to its high storage density,fast data transfer rate,long data life time and less energy consumption.Collinear holographic data storage technology is the typical solution of the holographic data storage technology which owns a more compact,compatible and practical system.This paper gives a brief review of holographic data storage,introduces collinear holographic data storage technology and discusses phase modulation technology being used in the holographic data storage system to achieve higher storage density and higher data transfer rate.

Optimization of Multiplex PCR Systems for Gene-chip Detection of Mutations in Exons in cTnI Gene Associated with FHCM

Hypertrophic cardiomyopathy (HCM) is one of the diseases damaging people health most badly and some mutations of exons in cardiac troponin I (cTnI) gene are closely associated with family hypertrophic cardiomyopathy (FHCM).A microarray was fabricated to screen mutations in exons 3,5,7,and 8 in cTnI gene.Primers were designed for the PCR (polymerase chain reaction) to amplify the target DNA fragments from fresh blood samples.In order to simplify the PCR process,multiplex PCR technology was investigated in detail.The concentration of Mg^(2+) played an important role in multiplex PCR process,a properly low concentration of Mg^(2+) submitted a better speciality of PCR products.The speciality was also favored when the annealing temperature was reasonably enhanced and 64℃is the optimal annealing temperature for the multiplex PCR systems.When applying the fabricated gene-chip to detect the target fragments from PCR mixture,the signal intensity sequence is in accordance with that from theoretic estimate.

厚热障涂层的失效分析研究

厚热障涂层因具有优异的隔热效果,在航空发动机热端部件防护上获得应用。在高温燃气冲蚀环境中服役后,致密厚热障涂层呈局部块状剥落而失效。本文对涂层失效后的截面形貌、元素分布、相结构等进行分析。结果表明,涂层失效的主要原因是表面附着物的渗入和焰流冲蚀下致密厚热障涂层内部应力的增加。采用高能等离子喷涂制备具有弥散分布裂纹的厚热障涂层有望提高涂层寿命。

Automated screening of primary cell-based aptamers for targeting and therapy of pancreatic cancer

Although it has been developed for many years, nucleic acid aptamer screening technology still fails to be widely used, a considerable part of it is due to the variability of tumor cell morphology, which leads to the use of immortalized cell lines in the laboratory to screen nucleic acid aptamers for recognition ability of tumor cells in the diseased body.To address this, primary cells that can be stably passaged were isolated and extracted from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice in this study.Next, an automated screening instrument for nucleic acid aptamers developed autonomously by our group was used to perform efficient aptamer screening using a limited number of cells, and the obtained nucleic acid aptamers were affinity verified at the cellular level.Finally, to answer the question of the cell growth environment difference on the recognition ability of nucleic acid aptamers, we verified its targeting ability to tumors in vivo on a nude mice xenograft tumor model, and further used a common antitumor drug doxorubicin combined with nucleic acid aptamers to verify the drug loading ability of this aptamer combined with the targeting therapeutic ability.