Biorefinery production of fuels and chemicals represents an attractive route for solving current energy crisis,as well as reducing green-house gas(GHG)emissions from ships,planes,and long-haul trucks.The current biore...Biorefinery production of fuels and chemicals represents an attractive route for solving current energy crisis,as well as reducing green-house gas(GHG)emissions from ships,planes,and long-haul trucks.The current biorefinery industry is under transition from the use of food(1G,1st generation),to the use of biomass(2G,2nd generation).Moreover,the use of atmospheric CO_(2)(3G,3rd generation)has caught increased attention as the possible next-generation biorefinery.Here we discuss how microorganisms can be engineered for CO_(2)-based biorefineries to produce fuels and chemicals.We start through reviewing different metabolic pathways that can be recruited for CO_(2)fixation,followed by different opportunities for CO_(2)fixation,either through co-consumption with sugars or used as the sole carbon source.Key challenges and future research directions for advancing 3rd-generation biorefineries are also be discussed.展开更多
基金the National Key Research and Development Program of China[2018YFA0903000]Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project[TSBICIPKJGG-009]+1 种基金National Natural Science Foundation of China[22011530113]Beijing Advanced Innovation Center for Soft Matter Science and Engineering.
文摘Biorefinery production of fuels and chemicals represents an attractive route for solving current energy crisis,as well as reducing green-house gas(GHG)emissions from ships,planes,and long-haul trucks.The current biorefinery industry is under transition from the use of food(1G,1st generation),to the use of biomass(2G,2nd generation).Moreover,the use of atmospheric CO_(2)(3G,3rd generation)has caught increased attention as the possible next-generation biorefinery.Here we discuss how microorganisms can be engineered for CO_(2)-based biorefineries to produce fuels and chemicals.We start through reviewing different metabolic pathways that can be recruited for CO_(2)fixation,followed by different opportunities for CO_(2)fixation,either through co-consumption with sugars or used as the sole carbon source.Key challenges and future research directions for advancing 3rd-generation biorefineries are also be discussed.
