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基于电子舌技术的氨基酸与密码子关系的初步研究
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作者 赵钊 程时文 +3 位作者 毛岳忠 应见喜 田师一 赵玉芬 《化学学报》 SCIE CAS CSCD 北大核心 2021年第11期1372-1375,共4页
自从首个遗传密码子被破译以来,密码子与所表达的氨基酸之间的关系一直吸引了许多关注.本研究从氨基酸、核苷和三偏磷酸钠的反应体系出发,用电子舌检测反应前后体系变化,考察核苷对氨基酸成肽反应的影响,试图找到氨基酸与密码子的联系.... 自从首个遗传密码子被破译以来,密码子与所表达的氨基酸之间的关系一直吸引了许多关注.本研究从氨基酸、核苷和三偏磷酸钠的反应体系出发,用电子舌检测反应前后体系变化,考察核苷对氨基酸成肽反应的影响,试图找到氨基酸与密码子的联系.结果表明,大部分氨基酸的密码子或反密码子中间位核苷对反应的促进作用最大,这种结果可能是因为核苷的碱基与氨基酸的侧链基团之间的某种弱相互作用导致的.相应地,亮氨酸和异亮氨酸之间的结果差异更加佐证了上述假设.这种弱相互作用有望成为研究密码子识别氨基酸的关键突破,为生命起源的研究提供新方法. 展开更多
关键词 密码子 氨基酸 电子舌 核苷 生命起源
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The Stevens law and the derivation of sensory perception 被引量:1
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作者 Jianshe Chen Shiyi Tian +2 位作者 Xinmiao Wang yuezhong mao Lei Zhao 《Journal of Future Foods》 2021年第1期82-87,共6页
The Stevens law,S=kI^(n),is commonly accepted as a landmark achievement in the field of sensory psychophysics and has been widely applied in food sensory research.The theory effectively links the two parameters of ver... The Stevens law,S=kI^(n),is commonly accepted as a landmark achievement in the field of sensory psychophysics and has been widely applied in food sensory research.The theory effectively links the two parameters of very different nature,the intensity of sensory perception(S)and the intensity of physical stimulus(I).However,the Stevens law suffers from two major drawbacks.The equation was self-inconsistent in terms of the units,which makes equation questionable in principle.The Stevens law was also found inapplicable when multiple physical stimuli are involved in the perception of a sensory attribute.To solve the first drawback,we propose to replace the absolute stimulation intensity in the Stevens law with a relative intensity,S=k(I/I_(0))^(n).The modified Stevens law becomes self-consistent when both sides of the equation are dimensionless and the theory is applicable regardless of the unit of the physical stimulus.To solve the second drawback,a concept of sensory derivation is introduced and so sensory properties can be categorized as primary sensory and derived sensory.The former can be described effectively by the Stevens law,while description of the latter is beyond the applicability of the Stevens law because of the involvement of multiple sensory stimuli or multi level sensory derivation.Furthermore,a sensory hierarch is constructed with sensory perception of different nature at different levels,including the primary sensory at the basic level and derived sensory perception at progressing levels.The modified Stevens law provides a self-consistent model for psychophysical analysis of sensory perception.The proposed sensory hierarchy helps to streamline sensory terms and attributes and may be used as a useful guide in establishing instrumental analysis of sensory perception. 展开更多
关键词 Stevens law Sensory derivation Sensory hierarch Sensory perception
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