The two major challenges in industrial enzymatic catalysis are the limited number of chemical reaction types that are catalyzed by enzymes and the instability of enzymes under harsh conditions in industrial catalysis....The two major challenges in industrial enzymatic catalysis are the limited number of chemical reaction types that are catalyzed by enzymes and the instability of enzymes under harsh conditions in industrial catalysis.Expanding enzyme catalysis to a larger substrate scope and greater variety of chemical reactions and tuning the microenvironment surrounding enzyme molecules to achieve high enzyme performance are urgently needed.In this account,we focus on our efforts using the de novo approach to synthesis hybrid enzyme catalysts that can address these two challenges and the structure-function relationship is discussed to reveal the principles of designing hybrid enzyme catalysts.We hope that this account will promote further efforts toward fundamental research and wide applications of designed enzyme hybrid catalysts for expanding biocatalysis.展开更多
When there is Doppler ambiguity number mutation,keystone formatting is no longer valid because of integration performance deterioration and false velocity estimation.A novel keystone formatting method based on non-bas...When there is Doppler ambiguity number mutation,keystone formatting is no longer valid because of integration performance deterioration and false velocity estimation.A novel keystone formatting method based on non-baseband interpolation is presented.It has a different half blind velocity range comparing with normal keystone formatting.Furthermore,there is non-superposition between half-blind-velocity-range of keystone formatting based on baseband and that of non-baseband interpolation.So a synthesizing keystone formatting is proposed to avoid the half-blind-velocity effect.Simulation results of the proposed method show that integration deterioration and velocity estimation falsity can be eliminated effectively.展开更多
In IP Multimedia Subsystem (IMS), the session setup delay is a critical value for Quality of Service (QoS). The existing approaches to improve this metric depend on optimization of Session Initiation Protocol (SIP) me...In IP Multimedia Subsystem (IMS), the session setup delay is a critical value for Quality of Service (QoS). The existing approaches to improve this metric depend on optimization of Session Initiation Protocol (SIP) message transmitting and signaling flows. Unfortunately, some service features are missing considered al-though they have been used widely in traditional 2G networks. This paper proposes a novel session setup scheme based on caching, upon the investigation of the performance of IMS session establishment. This mechanism involves cache based local routing policy and an adaptive caching algorithm, which can decrease call setup delay effectively as cached information in the terminating Serving-Call Session Control Function (S-CSCF) hit. The analytical model is deduced, as well as the delay and cost ratio functions are presented based on the model. Moreover, the analytical model is validated through the performance simulation in which the performance of the proposed novel method is evaluated against the basic session setup mechanism in terms of cost and delay.展开更多
文摘The two major challenges in industrial enzymatic catalysis are the limited number of chemical reaction types that are catalyzed by enzymes and the instability of enzymes under harsh conditions in industrial catalysis.Expanding enzyme catalysis to a larger substrate scope and greater variety of chemical reactions and tuning the microenvironment surrounding enzyme molecules to achieve high enzyme performance are urgently needed.In this account,we focus on our efforts using the de novo approach to synthesis hybrid enzyme catalysts that can address these two challenges and the structure-function relationship is discussed to reveal the principles of designing hybrid enzyme catalysts.We hope that this account will promote further efforts toward fundamental research and wide applications of designed enzyme hybrid catalysts for expanding biocatalysis.
基金supported by the National Natural Science Foundation of China(60871070)
文摘When there is Doppler ambiguity number mutation,keystone formatting is no longer valid because of integration performance deterioration and false velocity estimation.A novel keystone formatting method based on non-baseband interpolation is presented.It has a different half blind velocity range comparing with normal keystone formatting.Furthermore,there is non-superposition between half-blind-velocity-range of keystone formatting based on baseband and that of non-baseband interpolation.So a synthesizing keystone formatting is proposed to avoid the half-blind-velocity effect.Simulation results of the proposed method show that integration deterioration and velocity estimation falsity can be eliminated effectively.
文摘In IP Multimedia Subsystem (IMS), the session setup delay is a critical value for Quality of Service (QoS). The existing approaches to improve this metric depend on optimization of Session Initiation Protocol (SIP) message transmitting and signaling flows. Unfortunately, some service features are missing considered al-though they have been used widely in traditional 2G networks. This paper proposes a novel session setup scheme based on caching, upon the investigation of the performance of IMS session establishment. This mechanism involves cache based local routing policy and an adaptive caching algorithm, which can decrease call setup delay effectively as cached information in the terminating Serving-Call Session Control Function (S-CSCF) hit. The analytical model is deduced, as well as the delay and cost ratio functions are presented based on the model. Moreover, the analytical model is validated through the performance simulation in which the performance of the proposed novel method is evaluated against the basic session setup mechanism in terms of cost and delay.
