Good crystallinity can reduce the charge recombination centers caused by defects,whilst structures with strong polycondensation have high charge mobility,leading to more charge transfer to the material surface for rea...Good crystallinity can reduce the charge recombination centers caused by defects,whilst structures with strong polycondensation have high charge mobility,leading to more charge transfer to the material surface for reaction.Much effort has been put into the preparation of a highly efficient g-C_(3)N_(4) with defects to improve its application potential under the premise in high crystallinity.Hence,this review paper emphasizes the importance to balance the defect and crystallinity of g-C_(3)N_(4).In addition,detailed discussion on the relationship between defects and activity of g-C_(3)N_(4) was carried out based on its applications in environmental purification(e.g.,VOCs oxidation,NO_(x) oxidation,H_(2)O_(2) evolution,sterilization,pesticide oxidation)and energy conversion(H_(2) evolution,N_(2) fixation and CO_(2) reduction).Lastly,the challenge in developing more efficient defective g-C_(3)N_(4) photocatalytic materials is summarized.展开更多
The effective classification of urban domestic waste is the key to achieve a “waste-free city” and provides an essential guarantee for resource utilization. This article takes a coalitional game perspective to study...The effective classification of urban domestic waste is the key to achieve a “waste-free city” and provides an essential guarantee for resource utilization. This article takes a coalitional game perspective to study the dilemmas in urban domestic waste separation from the cooperative interaction of residents, government, and enterprises. The study finds that urban domestic waste classification in China is currently facing many problems, focusing on: 1) insufficient consensus among residents, 2) shortage of input funds, 3) corporate profitability difficulties, 4) weak policy constraints, and 5) difficulties in integrating goals. In this regard, each participating body still needs to focus on collective interests, coalitional games, break the dilemma society, and promote the long-term management of urban domestic waste.展开更多
Rural environmental pollution is becoming more and more serious, which has become an important problem to be solved urgently in our country under the background of the new era. Protecting the ecological environment is...Rural environmental pollution is becoming more and more serious, which has become an important problem to be solved urgently in our country under the background of the new era. Protecting the ecological environment is one of the important functions of the government, and protecting the rural water environment is the unshirkable responsibility of the local governments. As the main body of rural water pollution control, how to define and fulfill the local governments’ responsibilities is of great significance to the advancement of the overall governance work. This paper starts from the local governments, which are the important main body of rural environmental governance. By comparing the similarities and differences between the performance of government responsibilities under the traditional governance model and the collaborative governance model, clarifies the governance responsibilities of the local governments. And further explores the effective measures for the government to play the main role, fulfill the main responsibilities, and participate in the collaborative governance of rural water pollution.展开更多
Traditional Chinese medicine(TCM)has been passed down for more than 2,000 years.TCM beauty products driven by the principles of identification and treatment with various dosage forms and exhibit mild and safe efficacy...Traditional Chinese medicine(TCM)has been passed down for more than 2,000 years.TCM beauty products driven by the principles of identification and treatment with various dosage forms and exhibit mild and safe efficacy are bound to become a main component of the beauty industry in the future.Xu once commented that“Qian Jin Fang”is different from the traditional prescription system,which emphasizes the use of medicines.In this paper,we mainly selected the prescriptions for the treatment of disfigurement diseases such as acne,scarring,black dryness,face hyperpigmentation,black mole,and rosacea from the article titled,“Upper Seven Orifices Disease-Facial Medicine IX”in the Bei Ji Qian Jin Yao Fang[1].By studying and analyzing the original composition of the formula,understanding the etiology and pathogenesis of the disease,and exploring the characteristics of the formula concerning the efficacy of TCM,their properties,flavors,and meridians,we summarized the characteristics of the Qian Jin Fang.It is based on the external treatment of disfigurement diseases,with a wide variety of drugs,flexibility,and accuracy.This method draws upon analogies while utilizing excipients and harmonizers to focus on the combined healing approach of treatment and nourishment.展开更多
The development of metallic lithium anode is restrained by lithium dendrite growth during cycling.The solid polymer electrolyte with high mechanical strength and lithium ion conductivity could be applied to inhibit li...The development of metallic lithium anode is restrained by lithium dendrite growth during cycling.The solid polymer electrolyte with high mechanical strength and lithium ion conductivity could be applied to inhibit lithium dendrite growth.To prepare the high-performance solid polymer electrolyte,the environment-friendly and cheap bacterial cellulose(BC)is used as filler incorporating with PEO-based electrolyte owing to good mechanical properties and Li salts compatibility.PEO/Li TFSI/BC composite solid polymer electrolytes(CSPE)are prepared easily by aqueous mixing in water.The lithium ion transference number of PEO/Li TFSI/BC CSPE is 0.57,which is higher than PEO/Li TFSI solid polymer electrolyte(SPE)(0.409).The PEO/Li TFSI/BC CSPE exhibits larger tensile strength(4.43 MPa)than PEO/Li TFSI SPE(1.34 MPa).The electrochemical window of composite electrolyte is widened 1.43 V by adding BC.Density functional theory calculations indicate that flex of PEO chains around Li atoms is suppressed,suggesting the enhanced lithium ion conductivity.Frontier molecular orbitals results suggest that an unfavorable intermolecular charge transfer lead to achieve higher potential for BC composite electrolyte.All solid-state Li metal battery with PEO/Li TFSI/BC CSPE delivers longer cycle life for 600 cycles than PEO/Li TFSI SPE battery(50 cycles).Li symmetrical battery using PEO/Li TFSI/BC CSPE could be stable for 1160 h.展开更多
Avoiding cavitation inside the water jacket is one of the most important issues regarding the proper design of a diesel engine’s cylinder liner.Using CFD simulations conducted in the frame of a mixture multiphase app...Avoiding cavitation inside the water jacket is one of the most important issues regarding the proper design of a diesel engine’s cylinder liner.Using CFD simulations conducted in the frame of a mixture multiphase approach,a moving grid technology and near-wall cavitation model,in the present study the factors and fluid-dynamic patterns that influence cavitation are investigated from both macroscopic and mesoscopic perspectives.Several factors are examined,namely:wall vibration,water jacket width,initial cavitation bubble radius,coolant temperature,and number of bubbles.The results show that reducing the cylinder liner vibration intensity can significantly weaken the cavitation.Similarly,increasing the water jacket width is instrumental in avoiding cavitation.Increasing the coolant temperature reduces the microjet velocity related to bubble collapse,while increasing the number of bubbles produces a much larger water hammer pressure that can cause more damage to the cylinder liner.展开更多
This study was conducted to investigate the drug sensitivity of Escherichia coli isolated from sheep, providing data reference for clinical medication. Fifty-four samples were collected from a certain sheep farm in Ya...This study was conducted to investigate the drug sensitivity of Escherichia coli isolated from sheep, providing data reference for clinical medication. Fifty-four samples were collected from a certain sheep farm in Yangling, Shaanxi Province for E. coli isolation and identification, and K-B disk diffusion method was used to carry out the dug sensitivity test of 40 E. coli to the eight antimicrobials of spectinomycin, amikacin, tobramycin, enrofloxacin, nalidixic acid, levofloxacin, salafloxacin and ciprofloxacin. The results showed that there were 40 positive E. coli strains and the isolation rate was 74.7%. The resistance rates of the 40 E. coli to spectinomycin, amikacin,tobramycin and nalidixic acid were 85%, 95%, 97.5% and 87.5%, respectively, while the resistance rate to enrofloxacin, levofloxacin, salafloxacin and ciprofloxacin were relatively low and the resistance rates were 35%, 20%, 25% and 17.5%, respectively. The isolates showed different levels of drug resistance to eight antimicrobials and the highest resistance rate was 97.5%. It reminds that the sheep farm should strictly control the dosage according to the antimicrobial sensitive data in clinic.展开更多
Pulsed dielectric barrier discharge(PDBD) exhibits several applications in different fields;however,the interaction of its components with substances remains a key issue.In this study,we employed experimental and nume...Pulsed dielectric barrier discharge(PDBD) exhibits several applications in different fields;however,the interaction of its components with substances remains a key issue.In this study,we employed experimental and numerical modeling to investigate the interactions between different PDBD components and substances in pure helium and a helium-oxygen mixture.A membrane comprising a Staphylococcus aureus strain was utilized as the treatment object to demonstrate the trace actions of the evolutions and distributions of certain components on the surface of the substance.The results revealed that the shapes and sizes of the discharging area and inhibition zone differed between groups.Under a pure helium condition,a discharge layer existed along the membrane surface,lying beside the main discharging channel within the electrode area.Further,an annulus inhibition zone was formed at the outer edge of the electrode in the pure helium group at 30 s and 1 min,and this zone extended to a solid circle at 2 min with a radius that was~50% larger than that of the electrode radius.Nevertheless,the discharging channel and inhibition zone in the helium-oxygen mixture were constrained inside the electrode area without forming any annulus.A 2D symmetrical model was developed with COMSOL to simulate the spatiotemporal distributions of different particles over the membrane surface,and the result demonstrated that the main components,which formed the annulus inhibition zone under the pure helium condition,contributed to the high concentration of the He^(+)annulus that was formed at the outer edge of the electrode.Moreover,O^(+)and O_(2)^(+)were the main components that killed the bacteria under the helium-oxygen mixture conditions.These results reveal that the homogenization treatment on a material surface via PDBD is closely related to the treatment time and working gas.展开更多
The Yangjiang-Yitongdong Fault (YJF) is an important NW-trending regional fault, which divides the Zhujiang (Pearl) River Mouth Basin (ZRMB) into western and eastern segments. In Cenozoic, the northern continental mar...The Yangjiang-Yitongdong Fault (YJF) is an important NW-trending regional fault, which divides the Zhujiang (Pearl) River Mouth Basin (ZRMB) into western and eastern segments. In Cenozoic, the northern continental margin of the South China Sea (SCS) underwent continental rifting, breakup, seafloor spreading and thermal subsidence processes, and the Cenozoic activities of YJF is one part of this series of complex processes. Two long NW-trending multichannel seismic profiles located on both sides of the YJF extending from the continental shelf to Continent-Ocean Boundary (COB) were used to study the tectonic and sedimentary characteristics of western ZRMB. Using the 2D-Move software and back-stripping method, we constructed the balance cross-section model and calculated the fault activity rate. Through the comprehensive consideration of tectonic position, tectonic evolution history, featured structure, and stress analysis, we deduced the activity history of the YJF in Cenozoic. The results showed that the YJF can be divided into two segments by the central uplift belt. From 65 Ma to 32 Ma, the YJF was in sinistral motion as a whole, inherited the preexisting sinistral motion of Mesozoic YJF, in which, the southern part of YJF was mainly in extension activity, controlling the formation and evolution of Yunkai Low Uplift, coupled with slight sinistral motion. From 32 Ma to 23.8 Ma, the sinistral motion in northern part of YJF continued, while the sinistral motion in southern part began to stop or shifted to a slightly dextral motion. After 23.8 Ma, the dextral motion in southern part of YJF continued, while the sinistral motion in northern part of YJF gradually stopped, or shifted to the slightly dextral motion. The shift of the YJF strike-slip direction may be related to the magmatic underplating in continent-ocean transition, southeastern ZRMB. According to the analysis of tectonic activity intensity and rift sedimentary structure, the activities of YJF in Cenozoic played a regulating role in the rift extension process of ZRMB.展开更多
Safety of a compound Lonicera rupicola Hook. f. et & Thomson injection was evaluated by local irritation experiments including conjunctiva,skin and muscle irritant experiments,and the effect on weight gain was stu...Safety of a compound Lonicera rupicola Hook. f. et & Thomson injection was evaluated by local irritation experiments including conjunctiva,skin and muscle irritant experiments,and the effect on weight gain was studied. The results showed that the compound L. rupicola Hook. f. et & Thomson injection had no irritation to rabbit eyes and weak irritation to rabbit ears,and had relatively strong irritation to the leg muscles of the mice. Its metabolism in mice had no abnormal toxicity.展开更多
To analyze the causes affecting production situation of one pig farm in southwest region,group leader,assistant and related staffs in the pig farm were queried,mating and delivery situation of sow and dead-culling sit...To analyze the causes affecting production situation of one pig farm in southwest region,group leader,assistant and related staffs in the pig farm were queried,mating and delivery situation of sow and dead-culling situation ofpigletwere investigated.The results showed that(1) mating situation: mating 691 pigs,returning to love 42 pigs,abortion 4 pigs,mismatching rate was 7.59%.(2) Delivery situation: delivering 175 nests,total birth 2538,total piglet per fetus 14.5,average healthy piglet per fetus 10.12,invalid piglet rate was30.21%.Among them,mummy fetus,dead fetus,weak piglet and deformity accounted for 47.78%,35.64%,10.71% and 5.87% of invalid piglet.(3) Dead-culling situation: dead-culling rate in breeding process was 12.37%.Among them,diarrhea death wasthemain cause,accounting for 44.47%,followed by pressing,falling to the ground,disease,joint swelling,weakness and other causes,and they respectively accounted for 18.58%,13.36%,13.36%,8.56%,5.85% and 0.62%.展开更多
Acute pancreatitis(AP)is a devastating disease characterized by an inflammatory disorder of the pancreas.P-selectin glycoprotein ligand-1(PSGL-1)plays a crucial role in the initial steps of the adhesive at process to ...Acute pancreatitis(AP)is a devastating disease characterized by an inflammatory disorder of the pancreas.P-selectin glycoprotein ligand-1(PSGL-1)plays a crucial role in the initial steps of the adhesive at process to inflammatory sites,blockade of PSGL-1 might confer potent anti-inflammatory effects.In this study,we generated two non-human primate derived monoclonal antibodies capable of efficiently targeting human PSGL-1,RH001-6 and RH001-22,which were screened from immunized rhesus macaques.We found that RH001-6,can effectively block the binding of P-selectin to PSGL-1,and abolish the adhesion of leukocytes to endothelial cells in vitro.In vivo,we verified that RH001-6 relieved inflammatory responses and pancreatic injury in both caerulein and L-arginine induced AP models.We also evaluated the safety profile after RH001-6 treatment in mice,and verified that RH001-6 did not cause any significant pathological damages in vivo.Taken together,we developed a novel non-human primate derived PSGL-1 blocking antibody with high-specificity,named RH001-6,which can interrupt the binding of PSGL-1 and P-selectin and attenuate inflammatory responses during AP.Therefore,RH001-6 is highly potential to be further developed into therapeutics against acute inflammatory diseases,such as AP.展开更多
A thiourea precursor was employed to synthesize mesoporous carbon nitride(C3 N4) by a thermal polycondensation process with high surface area SiO2 and nanosphere SiO2 as two types of hard templates. The resultant meso...A thiourea precursor was employed to synthesize mesoporous carbon nitride(C3 N4) by a thermal polycondensation process with high surface area SiO2 and nanosphere SiO2 as two types of hard templates. The resultant mesoporous C3 N4 samples have high surface areas(105–112 m2/g) and mesopores with narrow sizes distribution(9.3 nm). Photocatalytic performance was evaluated by removal of NO in air under visible light irradiation. The results showed that mesoporous C3 N4 samples exhibited significantly improved photocatalytic activity in comparison with bulk C3 N4, which also exceeded that of N-doped TiO2 and C-doped TiO2. The activity enhancement can be ascribed to the synergistic effects of large surface area and pore volume, enhanced light-harvesting ability, increased redox potential, and reduced recombination of charge carriers. In addition to the high activity, the mesoporous C3 N4 samples also showed high photochemical stability. The mesoporous C3 N4 photocatalysts with enhanced and durable activity could provide a new efficient material for environmental pollution control.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.52370109)China Postdoctoral Science Foundation(2022M710830)+4 种基金Venture and Innovation Support Program for Chongqing Overseas Returnees(cx2022005)the Natural Science Foun-dation Project of CQ CSTC(CSTB2022NSCQ-MSX1267)Research Project of Chongqing Education Commission Foundation(KJQN201800826)Science and Technology Research Program of Chongqing Municipal Education Commission of China(KJZD-K202100801)Post-doctoral Program Funded by Chongqing,and Chongqing Technology and Business University,China(CXQT21023).
文摘Good crystallinity can reduce the charge recombination centers caused by defects,whilst structures with strong polycondensation have high charge mobility,leading to more charge transfer to the material surface for reaction.Much effort has been put into the preparation of a highly efficient g-C_(3)N_(4) with defects to improve its application potential under the premise in high crystallinity.Hence,this review paper emphasizes the importance to balance the defect and crystallinity of g-C_(3)N_(4).In addition,detailed discussion on the relationship between defects and activity of g-C_(3)N_(4) was carried out based on its applications in environmental purification(e.g.,VOCs oxidation,NO_(x) oxidation,H_(2)O_(2) evolution,sterilization,pesticide oxidation)and energy conversion(H_(2) evolution,N_(2) fixation and CO_(2) reduction).Lastly,the challenge in developing more efficient defective g-C_(3)N_(4) photocatalytic materials is summarized.
文摘The effective classification of urban domestic waste is the key to achieve a “waste-free city” and provides an essential guarantee for resource utilization. This article takes a coalitional game perspective to study the dilemmas in urban domestic waste separation from the cooperative interaction of residents, government, and enterprises. The study finds that urban domestic waste classification in China is currently facing many problems, focusing on: 1) insufficient consensus among residents, 2) shortage of input funds, 3) corporate profitability difficulties, 4) weak policy constraints, and 5) difficulties in integrating goals. In this regard, each participating body still needs to focus on collective interests, coalitional games, break the dilemma society, and promote the long-term management of urban domestic waste.
文摘Rural environmental pollution is becoming more and more serious, which has become an important problem to be solved urgently in our country under the background of the new era. Protecting the ecological environment is one of the important functions of the government, and protecting the rural water environment is the unshirkable responsibility of the local governments. As the main body of rural water pollution control, how to define and fulfill the local governments’ responsibilities is of great significance to the advancement of the overall governance work. This paper starts from the local governments, which are the important main body of rural environmental governance. By comparing the similarities and differences between the performance of government responsibilities under the traditional governance model and the collaborative governance model, clarifies the governance responsibilities of the local governments. And further explores the effective measures for the government to play the main role, fulfill the main responsibilities, and participate in the collaborative governance of rural water pollution.
文摘Traditional Chinese medicine(TCM)has been passed down for more than 2,000 years.TCM beauty products driven by the principles of identification and treatment with various dosage forms and exhibit mild and safe efficacy are bound to become a main component of the beauty industry in the future.Xu once commented that“Qian Jin Fang”is different from the traditional prescription system,which emphasizes the use of medicines.In this paper,we mainly selected the prescriptions for the treatment of disfigurement diseases such as acne,scarring,black dryness,face hyperpigmentation,black mole,and rosacea from the article titled,“Upper Seven Orifices Disease-Facial Medicine IX”in the Bei Ji Qian Jin Yao Fang[1].By studying and analyzing the original composition of the formula,understanding the etiology and pathogenesis of the disease,and exploring the characteristics of the formula concerning the efficacy of TCM,their properties,flavors,and meridians,we summarized the characteristics of the Qian Jin Fang.It is based on the external treatment of disfigurement diseases,with a wide variety of drugs,flexibility,and accuracy.This method draws upon analogies while utilizing excipients and harmonizers to focus on the combined healing approach of treatment and nourishment.
基金supported partialy by the National Natural Science Foundation of China(No.51973171)Young Talent Support Plan of Xi’an Jiaotong University and Innovation Capability Support Program of Shaanxi(No.2018PT-28,2019PT-05)
文摘The development of metallic lithium anode is restrained by lithium dendrite growth during cycling.The solid polymer electrolyte with high mechanical strength and lithium ion conductivity could be applied to inhibit lithium dendrite growth.To prepare the high-performance solid polymer electrolyte,the environment-friendly and cheap bacterial cellulose(BC)is used as filler incorporating with PEO-based electrolyte owing to good mechanical properties and Li salts compatibility.PEO/Li TFSI/BC composite solid polymer electrolytes(CSPE)are prepared easily by aqueous mixing in water.The lithium ion transference number of PEO/Li TFSI/BC CSPE is 0.57,which is higher than PEO/Li TFSI solid polymer electrolyte(SPE)(0.409).The PEO/Li TFSI/BC CSPE exhibits larger tensile strength(4.43 MPa)than PEO/Li TFSI SPE(1.34 MPa).The electrochemical window of composite electrolyte is widened 1.43 V by adding BC.Density functional theory calculations indicate that flex of PEO chains around Li atoms is suppressed,suggesting the enhanced lithium ion conductivity.Frontier molecular orbitals results suggest that an unfavorable intermolecular charge transfer lead to achieve higher potential for BC composite electrolyte.All solid-state Li metal battery with PEO/Li TFSI/BC CSPE delivers longer cycle life for 600 cycles than PEO/Li TFSI SPE battery(50 cycles).Li symmetrical battery using PEO/Li TFSI/BC CSPE could be stable for 1160 h.
基金supported by the Science Fund of the State Key Laboratory of Engine Reliability(No.SKLER-201902).
文摘Avoiding cavitation inside the water jacket is one of the most important issues regarding the proper design of a diesel engine’s cylinder liner.Using CFD simulations conducted in the frame of a mixture multiphase approach,a moving grid technology and near-wall cavitation model,in the present study the factors and fluid-dynamic patterns that influence cavitation are investigated from both macroscopic and mesoscopic perspectives.Several factors are examined,namely:wall vibration,water jacket width,initial cavitation bubble radius,coolant temperature,and number of bubbles.The results show that reducing the cylinder liner vibration intensity can significantly weaken the cavitation.Similarly,increasing the water jacket width is instrumental in avoiding cavitation.Increasing the coolant temperature reduces the microjet velocity related to bubble collapse,while increasing the number of bubbles produces a much larger water hammer pressure that can cause more damage to the cylinder liner.
基金Supported by the Fundamental Research Funds for the Central Universities:the Young Teachers Fund of Southwest Minzu University(2017NZYQN38)Innovative Scientific Research Project for Postgraduates of Southwest Minzu University(CX2018SZ42)
文摘This study was conducted to investigate the drug sensitivity of Escherichia coli isolated from sheep, providing data reference for clinical medication. Fifty-four samples were collected from a certain sheep farm in Yangling, Shaanxi Province for E. coli isolation and identification, and K-B disk diffusion method was used to carry out the dug sensitivity test of 40 E. coli to the eight antimicrobials of spectinomycin, amikacin, tobramycin, enrofloxacin, nalidixic acid, levofloxacin, salafloxacin and ciprofloxacin. The results showed that there were 40 positive E. coli strains and the isolation rate was 74.7%. The resistance rates of the 40 E. coli to spectinomycin, amikacin,tobramycin and nalidixic acid were 85%, 95%, 97.5% and 87.5%, respectively, while the resistance rate to enrofloxacin, levofloxacin, salafloxacin and ciprofloxacin were relatively low and the resistance rates were 35%, 20%, 25% and 17.5%, respectively. The isolates showed different levels of drug resistance to eight antimicrobials and the highest resistance rate was 97.5%. It reminds that the sheep farm should strictly control the dosage according to the antimicrobial sensitive data in clinic.
基金supported by National Natural Science Foundation of China(No.51907076)the Interdisciplinary Fund of the Wuhan National High Magnetic Field Center(No.WHMFC202101)
文摘Pulsed dielectric barrier discharge(PDBD) exhibits several applications in different fields;however,the interaction of its components with substances remains a key issue.In this study,we employed experimental and numerical modeling to investigate the interactions between different PDBD components and substances in pure helium and a helium-oxygen mixture.A membrane comprising a Staphylococcus aureus strain was utilized as the treatment object to demonstrate the trace actions of the evolutions and distributions of certain components on the surface of the substance.The results revealed that the shapes and sizes of the discharging area and inhibition zone differed between groups.Under a pure helium condition,a discharge layer existed along the membrane surface,lying beside the main discharging channel within the electrode area.Further,an annulus inhibition zone was formed at the outer edge of the electrode in the pure helium group at 30 s and 1 min,and this zone extended to a solid circle at 2 min with a radius that was~50% larger than that of the electrode radius.Nevertheless,the discharging channel and inhibition zone in the helium-oxygen mixture were constrained inside the electrode area without forming any annulus.A 2D symmetrical model was developed with COMSOL to simulate the spatiotemporal distributions of different particles over the membrane surface,and the result demonstrated that the main components,which formed the annulus inhibition zone under the pure helium condition,contributed to the high concentration of the He^(+)annulus that was formed at the outer edge of the electrode.Moreover,O^(+)and O_(2)^(+)were the main components that killed the bacteria under the helium-oxygen mixture conditions.These results reveal that the homogenization treatment on a material surface via PDBD is closely related to the treatment time and working gas.
基金supported by the National Natural Science Foundation of China(51672312,21373275,51808080,21571192)the Fundamental Research Funds for the Central Univsrsity,South-Central University for Nationalities(CZT19006)+2 种基金the Natural Science Foundation Project of CQ CSTC(cstc2018jcyjA 3794)China "post-doctoral innovative talent support program"(BX20180056)China Postdoctoral Science Foundation(2018M643788XB)~~
基金The National Natural Science Foundation of China under contract Nos 41776072,41476039,41674092 and 41676045the Geotectonic Evolution of China and Compilation of International Asian Geotectonic Map under contract No.DD20190364the Marine Basic Geological Survey Project under contract No.DD20190627
文摘The Yangjiang-Yitongdong Fault (YJF) is an important NW-trending regional fault, which divides the Zhujiang (Pearl) River Mouth Basin (ZRMB) into western and eastern segments. In Cenozoic, the northern continental margin of the South China Sea (SCS) underwent continental rifting, breakup, seafloor spreading and thermal subsidence processes, and the Cenozoic activities of YJF is one part of this series of complex processes. Two long NW-trending multichannel seismic profiles located on both sides of the YJF extending from the continental shelf to Continent-Ocean Boundary (COB) were used to study the tectonic and sedimentary characteristics of western ZRMB. Using the 2D-Move software and back-stripping method, we constructed the balance cross-section model and calculated the fault activity rate. Through the comprehensive consideration of tectonic position, tectonic evolution history, featured structure, and stress analysis, we deduced the activity history of the YJF in Cenozoic. The results showed that the YJF can be divided into two segments by the central uplift belt. From 65 Ma to 32 Ma, the YJF was in sinistral motion as a whole, inherited the preexisting sinistral motion of Mesozoic YJF, in which, the southern part of YJF was mainly in extension activity, controlling the formation and evolution of Yunkai Low Uplift, coupled with slight sinistral motion. From 32 Ma to 23.8 Ma, the sinistral motion in northern part of YJF continued, while the sinistral motion in southern part began to stop or shifted to a slightly dextral motion. After 23.8 Ma, the dextral motion in southern part of YJF continued, while the sinistral motion in northern part of YJF gradually stopped, or shifted to the slightly dextral motion. The shift of the YJF strike-slip direction may be related to the magmatic underplating in continent-ocean transition, southeastern ZRMB. According to the analysis of tectonic activity intensity and rift sedimentary structure, the activities of YJF in Cenozoic played a regulating role in the rift extension process of ZRMB.
基金supported by the National Natural Science Foundation of China(51672312,21571192,21373275)the Science and Technology Program of Wuhan(2016010101010018,2015070504020220)+1 种基金the Key Project in the National Science&Technology Pillar Program during the Twelfth Five-Year Plan Period(2015BAB01B01)the Natural Science Foundation of South-Central University for Nationalities(XTZ15016,CZP17062)~~
基金Supported by Project of Science and Technology Department of Sichuan Province,China(2016KZ0007)Innovative Scientific Research Project for Postgraduates of Southwest Minzu University(CX2018SZ44)
文摘Safety of a compound Lonicera rupicola Hook. f. et & Thomson injection was evaluated by local irritation experiments including conjunctiva,skin and muscle irritant experiments,and the effect on weight gain was studied. The results showed that the compound L. rupicola Hook. f. et & Thomson injection had no irritation to rabbit eyes and weak irritation to rabbit ears,and had relatively strong irritation to the leg muscles of the mice. Its metabolism in mice had no abnormal toxicity.
基金Supported by the Fundamental Research Funds for the Central Universities:the Young Teachers Fund of Southwest Minzu University(2017NZYQN38)Innovative Scientific Research Project for Postgraduates of Southwest Minzu University(CX2018SZ43)
文摘To analyze the causes affecting production situation of one pig farm in southwest region,group leader,assistant and related staffs in the pig farm were queried,mating and delivery situation of sow and dead-culling situation ofpigletwere investigated.The results showed that(1) mating situation: mating 691 pigs,returning to love 42 pigs,abortion 4 pigs,mismatching rate was 7.59%.(2) Delivery situation: delivering 175 nests,total birth 2538,total piglet per fetus 14.5,average healthy piglet per fetus 10.12,invalid piglet rate was30.21%.Among them,mummy fetus,dead fetus,weak piglet and deformity accounted for 47.78%,35.64%,10.71% and 5.87% of invalid piglet.(3) Dead-culling situation: dead-culling rate in breeding process was 12.37%.Among them,diarrhea death wasthemain cause,accounting for 44.47%,followed by pressing,falling to the ground,disease,joint swelling,weakness and other causes,and they respectively accounted for 18.58%,13.36%,13.36%,8.56%,5.85% and 0.62%.
基金supported by Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (CAMS,2021-I2M1-072,China)National Natural Science Foundation of China (82161138027 and 81970358)。
文摘Acute pancreatitis(AP)is a devastating disease characterized by an inflammatory disorder of the pancreas.P-selectin glycoprotein ligand-1(PSGL-1)plays a crucial role in the initial steps of the adhesive at process to inflammatory sites,blockade of PSGL-1 might confer potent anti-inflammatory effects.In this study,we generated two non-human primate derived monoclonal antibodies capable of efficiently targeting human PSGL-1,RH001-6 and RH001-22,which were screened from immunized rhesus macaques.We found that RH001-6,can effectively block the binding of P-selectin to PSGL-1,and abolish the adhesion of leukocytes to endothelial cells in vitro.In vivo,we verified that RH001-6 relieved inflammatory responses and pancreatic injury in both caerulein and L-arginine induced AP models.We also evaluated the safety profile after RH001-6 treatment in mice,and verified that RH001-6 did not cause any significant pathological damages in vivo.Taken together,we developed a novel non-human primate derived PSGL-1 blocking antibody with high-specificity,named RH001-6,which can interrupt the binding of PSGL-1 and P-selectin and attenuate inflammatory responses during AP.Therefore,RH001-6 is highly potential to be further developed into therapeutics against acute inflammatory diseases,such as AP.
基金supported by the National Natural Science Foundation of China(51108487)the Natural Science Foundation Project of CQ CSTC(cstc2013jcyjA20018)+2 种基金the Science and Technology Project from Chongqing Education Commission(KJ130725)the Innovative Research Team Development Program in University of Chongqing(KJTD201314)the Opening Project of Key Laboratory of Green Catalysis of Sichuan Institutes of Higher Education(LZJ1204)
文摘A thiourea precursor was employed to synthesize mesoporous carbon nitride(C3 N4) by a thermal polycondensation process with high surface area SiO2 and nanosphere SiO2 as two types of hard templates. The resultant mesoporous C3 N4 samples have high surface areas(105–112 m2/g) and mesopores with narrow sizes distribution(9.3 nm). Photocatalytic performance was evaluated by removal of NO in air under visible light irradiation. The results showed that mesoporous C3 N4 samples exhibited significantly improved photocatalytic activity in comparison with bulk C3 N4, which also exceeded that of N-doped TiO2 and C-doped TiO2. The activity enhancement can be ascribed to the synergistic effects of large surface area and pore volume, enhanced light-harvesting ability, increased redox potential, and reduced recombination of charge carriers. In addition to the high activity, the mesoporous C3 N4 samples also showed high photochemical stability. The mesoporous C3 N4 photocatalysts with enhanced and durable activity could provide a new efficient material for environmental pollution control.