Clinical Study on the Impact of Long-term Survival Quality in 204 Postoperative Patients with Breast Cancer by Cox Proportional Hazard Models

The aim of study was to evaluate clinical characteristics, social support and the association with the prognosis of breast cancer patients. A total of 204 participants were followed from 2003 until the end of 2008. Information about patients with breast cancer was submitted by investigators. Data were analyzed by Cox’s proportional hazard model. The clinical staging of breast cancer we used was the TNM classification. A 'T' score is based upon the size and/or extent of invasion. The 'N' score indicates the extent of lymph node involvement. Age at diagnose was associated with protective factors (HR=0.972;95%CI (0.834-1.130)), T staging (HR=2.075;95%CI (1.424-3.022)), N staging (HR=1.513;95%CI (1.066-2.148)), were associated with risk factor. Two survival graphs of nodes with negative effects by histology and nodes with positive effects by histology was analyzed by log-rank test, there was statistically significant relationship between two survival graphs (χ2 =136.8467, p <.0001). Age at diagnoses, Clinical stage tumor and node could contribute to the development of breast cancer and disease free survival in Chinese women.

Living status and support system of children orphaned by AIDS in central China—Description and policy recommendations

This study aimed to research the living status and support system of children orphaned by AIDS in rural Henan Province. The approach of face-to-face questionnaires research was used to assess 501 children’s current situation while in-depth interview was conducted for the support system research. The age range of the children orphaned by AIDS was 2 - 15 years old and the mean age was 11.10 years. Most children among 2 - 6 years had communication skills with temper control and psychological problems. Children of 7 - 15 years old had the ability to take care of themselves and family members but could not do self-regulation. The support system for children orphaned by AIDS included social support, policies support, education support, and health care support but improvement are needed in the future. Support system can be improved through much more feasible and concrete policies and strategies to guarantee these children’s basic needs and comprehensive development.

Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive use

The authors performed a meta-analysis of case-control studies that addressed whether reproductive factors and oral contraceptive use were associated with breast cancer by searching the MEDLINE,PubMed,Proquest,Embase,ScienceDirect,African Healthline,BMJ Health Intelligence and Chinese Periodical net databases for all English-language and Chinese-language papers published from January 1,1997 to December 31,2007.A total of 15 studies calculating pool ORs indicated that menopausal age>50 yr[odds ratio(OR),1.39;95%confidence interval(CI),1.22–1.57]and oral contraceptive use(OR,2.12*,“*”:summary OR was adjusted;95%CI,1.24–3.62)were correlated with the increase in breast cancer risk while the summary OR based on number of full-term pregnancies≥1(OR,0.63*;95%CI,0.60–0.68)and breast-feeding(OR,0.76;95%CI,0.64–0.90)indicated no association with breast cancer risk.The correlation was statistically significant.Menopausal age>50 yr and oral contraceptive use are positively correlated with an increase in breast cancer risk while breast-feeding and number of full-term pregnancies≥1 are protective factors.

Soy food consumption in relation to breast cancer modified by menopause status

It has been found that lifestyle and diet are associated with the development of cancers.The mortality of breast cancer in Wuhan city is increasing,according to the statistics of recent years.This case control study was aimed to provide data for alimentary therapeutics for breast carcinomas.It included a case group(n 5196)and an age frequency-matched control group(n 5202).A validated food frequency questionnaire was used to obtain information on usual food consumption.The results indicate that intake of soy foods more than 5 times per week was associated with a decreased risk of breast cancer,especially in premenopausal women.The adjusted OR was 0.294[95%CI was(0.158–0.546),P 50.000].Our results indicate that alimentary therapeutics for breast cancer can be adjusted by status of menopause.