Effects of PCI on the levels of WBC, CD40L and cTnI in patients with ST segment elevation myocardial infarction combined with arrhythmia

Objective:Toanalyze the effect of PCI treatment on blood WBC(White blood cell),CD40 L and cTnI(Cardiac Troponin I)levels and prognosis in patients with ST segment elevation myocardial infarction combined with arrhythmia at different time windows.Methods 87 patients with arrhythmia who were treated from January 2017 to January 2019 were seleted as the research objects.They were divided into≤3 h group,3 to 6 h group,and 6 to 12 h group according to the PCI treatment time window.Patients were treated by PCI in all groups.The recanalization and reperfusion arrhythmia of patients after vascular occlusion were investigated.The WBC,cTnI,and CD40 L levels in patients'serum were measured at the time of enrollment and 24 hours after the end of treatment.Result The vascular recanalization rate was significantly different in the three groups,and the difference was statistically significant(P<0.05).The vascular recanalization rate was the highest in the≤3 h group and the lowest in the 6-12 h group.There was a significant difference in the incidence of reperfusion arrhythmia among the three groups(P<0.05),of which the incidence rate was the highest in the≤3 h group,and the time of the occurrence of reperfusion arrhythmia in the three groups was significantly different,and the difference was statistically significant(P<0.05).The time of the occurrence of reperfusion arrhythmia was highest in the 6-12 h group,there was no significant difference in time between the≤3 h group and the 3-6 h group(P>0.05.There were significant differences in WBC,CD40L and cTnI levels in the three groups,and the differences were statistically significant(P<0.05).The serum WBC,CD40L and cTnI levels were highest in≤3 h group,but there was no significant difference in WBC,CD40L and cTnI levels in the 3-6 h group and 6-12 group.Conclusion The best time window of PCI treatment is 3~6h in patients with arrhythmia,which can significantly improve the levels of serum WBC,CD40L and cTnI.