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Progress of intravoxel incoherent motion diffusion-weighted imaging in liver diseases 被引量:7
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作者 yun-yun tao Yi Zhou +5 位作者 Ran Wang Xue-Qin Gong Jing Zheng Cui Yang Lin Yang Xiao-Ming Zhang 《World Journal of Clinical Cases》 SCIE 2020年第15期3164-3176,共13页
Traditional magnetic resonance(MR)diffusion-weighted imaging(DWI)uses a single exponential model to obtain the apparent diffusion coefficient to quantitatively reflect the diffusion motion of water molecules in living... Traditional magnetic resonance(MR)diffusion-weighted imaging(DWI)uses a single exponential model to obtain the apparent diffusion coefficient to quantitatively reflect the diffusion motion of water molecules in living tissues,but it is affected by blood perfusion.Intravoxel incoherent motion(IVIM)-DWI utilizes a double-exponential model to obtain information on pure water molecule diffusion and microcirculatory perfusion-related diffusion,which compensates for the insufficiency of traditional DWI.In recent years,research on the application of IVIM-DWI in the diagnosis and treatment of hepatic diseases has gradually increased and has achieved considerable progress.This study mainly reviews the basic principles of IVIM-DWI and related research progress in the diagnosis and treatment of hepatic diseases. 展开更多
关键词 Magnetic resonance imaging Diffusion magnetic resonance imaging Liver diseases Liver cirrhosis CARCINOMA CHOLANGIOCARCINOMA
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Cervical aortic arch with aneurysm formation and an anomalous right subclavian artery and left vertebral artery:A case report
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作者 Yao-Kun Wu Qi Mao +7 位作者 Mao-Ting Zhou Ning Liu Xi Yu Jin-Cheng Peng yun-yun tao Xue-Qin Gong Lin Yang Xiao-Ming Zhang 《World Journal of Clinical Cases》 SCIE 2022年第10期3291-3296,共6页
BACKGROUND A cervical aortic arch(CAA)refers to a high-riding aortic arch(AA)that often extends above the level of the clavicle.This condition is very rare,with an incidence of less than 1/10000.CASE SUMMARY A 29-year... BACKGROUND A cervical aortic arch(CAA)refers to a high-riding aortic arch(AA)that often extends above the level of the clavicle.This condition is very rare,with an incidence of less than 1/10000.CASE SUMMARY A 29-year-old woman was admitted to the otolaryngology department of our hospital for repeated bilateral purulent nasal discharge for the prior 3 mo.The patient was diagnosed with chronic sinusitis and chronic rhinitis at admission.A preoperative noncontrast chest computed tomography scan showed a high-riding,tortuous AA extending to the mid-upper level of the first thoracic vertebra with local cystic dilatation.A further computed tomography angiography examination showed that the brachiocephalic trunk,left common carotid artery,left vertebral artery(LVA)(slender),and left subclavian artery sequentially branched off of the aorta from the proximal end to the distal end of the AA.The proximal end of the right subclavian artery(RSCA)was tortuous and dilated.The AA showed tumorlike local expansion,with a maximum diameter of approximately 4 cm.After consultation with the department of cardiac macrovascular surgery,the patient was diagnosed with left CAA with aneurysm formation and an anomalous RSCA and LVA and was transferred to that department.The patient underwent AA aneurysm resection and artificial blood vessel replacement under general anesthesia and cardiopulmonary bypass.No abnormality was found during the 2-mo follow-up after discharge.CONCLUSION A CAA is a rare congenital anomaly of vascular development.The present unique case of CAA with aneurysm formation and an anomalous RSCA and LVA enriches existing CAA data. 展开更多
关键词 Cervical aortic arch Aortic aneurysm Aortic anomaly Computed tomography angiography Haughton classification Case report
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利用静电纺丝技术制备聚己内酯-胶原复合包载碱性成纤维细胞生长因子手术缝纫线及其缓释性能的研究 被引量:3
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作者 宋奕 张翠云 +6 位作者 李奕 张素素 潘舜 陶云云 许璐摇 何华成 吴疆 《中国生物工程杂志》 CAS CSCD 北大核心 2019年第1期55-62,共8页
目的:制备具有碱性成纤维细胞生长因子缓释性能手术缝纫线的复合材料,并探究其机械性能和体外释药情况。方法:利用静电纺丝技术,通过研究复合材料中物质成分的配比,优化包载效率,并研究聚己内酯-胶原复合结构(PCL-Col)对可控释放bFGF的... 目的:制备具有碱性成纤维细胞生长因子缓释性能手术缝纫线的复合材料,并探究其机械性能和体外释药情况。方法:利用静电纺丝技术,通过研究复合材料中物质成分的配比,优化包载效率,并研究聚己内酯-胶原复合结构(PCL-Col)对可控释放bFGF的影响来制备具有生物活性与药物缓释性能的手术缝纫线;观察缝纫线微观结构,检测缝纫线机械性能和载药量。结果:通过扫描电镜结果证明载药的手术缝纫线具有完整的线状结构。进一步通过拉伸与拉伸循环实验证明缝纫线具有良好的机械性能,最后通过酶联免疫吸附实验(enzyme linked immunosorbent assay,ELISA)证明所制备的手术缝纫线具备一定的药物缓释性能。结论:通过静电纺丝装置,优化纺丝参数,成功制备了PCL-Col-bFGF的手术缝线复合材料。该缝纫线满足缝合所需要的机械性能同时具备一定的bFGF缓释性能。 展开更多
关键词 静电纺丝 生长因子 机械性能 缓释性能
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