Dear Editor,Coxsackievirus A16(CA16)is one of the major viral pathogens associated with hand,foot,and mouth disease.CA16 belongs to the Enterovirus genus of the Picornaviridae family and possesses a single-stranded po...Dear Editor,Coxsackievirus A16(CA16)is one of the major viral pathogens associated with hand,foot,and mouth disease.CA16 belongs to the Enterovirus genus of the Picornaviridae family and possesses a single-stranded positivesense RNA genome(Mao et al.,2014).Reverse genetics is an important tool for CA16 research.Previously,a reverse genetics T7 polymerase-based system was de-展开更多
Dear Editor,The identification of novel serum biomarkers holds great value for diagnosing and monitoring disease conditions due to its convenient and non-invasive nature.Recently,great interests have been shed on seru...Dear Editor,The identification of novel serum biomarkers holds great value for diagnosing and monitoring disease conditions due to its convenient and non-invasive nature.Recently,great interests have been shed on serum microRNAs(miRNAs),which emerge as promising biomarkers for a variety of diseases including cancer and metabolic disorders(Cortez et al.,2011).Despite the concentrated attention on serum miRNAs,the reports on the existence and diagnostic value of other serum small RNAs remain surprisingly few.In present study.展开更多
基金supported by grants from the Science and Technology Commission of Shanghai Municipality (13ZR1462900)the Shanghai Institutes for Biological Science (SIBS),Chinese Academy of Science (CAS) (2013KIP317)+1 种基金the support of the SA-SIBS scholarship programYouth Innovation Promotion Association of CAS (2016249)
文摘Dear Editor,Coxsackievirus A16(CA16)is one of the major viral pathogens associated with hand,foot,and mouth disease.CA16 belongs to the Enterovirus genus of the Picornaviridae family and possesses a single-stranded positivesense RNA genome(Mao et al.,2014).Reverse genetics is an important tool for CA16 research.Previously,a reverse genetics T7 polymerase-based system was de-
基金supported by National Basic Research Program of China(2011CB944401 and 2011CB710905)Strategic Priority Research Program of the Chinese Academy of Sciences(XDA 01010202)National Natural Science Foundation of China(31200879 and 31300957)
文摘Dear Editor,The identification of novel serum biomarkers holds great value for diagnosing and monitoring disease conditions due to its convenient and non-invasive nature.Recently,great interests have been shed on serum microRNAs(miRNAs),which emerge as promising biomarkers for a variety of diseases including cancer and metabolic disorders(Cortez et al.,2011).Despite the concentrated attention on serum miRNAs,the reports on the existence and diagnostic value of other serum small RNAs remain surprisingly few.In present study.
