In this paper, wave-body interactions under the effects of complex topography are investigated numerically by a two-phase incompressible Reynolds-Averaged Navier-Stokes(RANS) solver in OpenFOAM. A submerged bottom-sta...In this paper, wave-body interactions under the effects of complex topography are investigated numerically by a two-phase incompressible Reynolds-Averaged Navier-Stokes(RANS) solver in OpenFOAM. A submerged bottom-standing structure is distributed below the floating body, and the effects of the water depth and top width of the submerged structure on wave-body interactions are studied. The results show that the submerged structure can affect wave loads and roll motion. The vertical force can be amplified on the fixed body when the water depth of the submerged structure is smaller than half of the water depth of the body. The top width significantly affects the vertical force when the top width is smaller than the incident wave length and larger than the body width. For the free-rolling body, roll amplitude can be increased when the ratio of the incident wave length to the water depth of the submerged structure is large enough. On the resonance condition, roll amplitude is slightly reduced by the submerged structure. The effects of the top width on roll amplitude are remarkable when special conditions are fulfilled.展开更多
Many discrete systems have more distinctive dynamical behaviors compared to continuous ones,which has led lots of researchers to investigate them.The discrete predatorprey model with two different functional responses...Many discrete systems have more distinctive dynamical behaviors compared to continuous ones,which has led lots of researchers to investigate them.The discrete predatorprey model with two different functional responses(Holling type I and II functional responses)is discussed in this paper,which depicts a complex population relationship.The local dynamical behaviors of the interior fixed point of this system are studied.The detailed analysis reveals this system undergoes flip bifurcation and Neimark-Sacker bifurcation.Especially,we prove the existence of Marotto's chaos by analytical method.In addition,the hybrid control method is applied to control the chaos of this system.Numerical simulations are presented to support our research and demonstrate new dynamical behaviors,such as period-10,19,29,39,48 orbits and chaos in the sense of Li-Yorke.展开更多
C-repeat binding factors(CBFs)are well-known transcription factors(TFs)that regulate plant cold acclimation.RNA sequencing(RNA-seq)data from diverse plant species provide opportunities to identify other TFs involved i...C-repeat binding factors(CBFs)are well-known transcription factors(TFs)that regulate plant cold acclimation.RNA sequencing(RNA-seq)data from diverse plant species provide opportunities to identify other TFs involved in the cold response.However,this task is challenging because gene gain and loss has led to an intertwined community of co-orthologs and in-paralogs between and within species.Using orthogroup(closely related homologs)analysis,we identified 10,549 orthogroups in five representative eudicots.A phylotranscriptomic analysis of cold-treated seedlings from eudicots identified 35 high-confidence conserved cold-responsive transcription factor orthogroups(CoCoFos).These 35 CoCoFos included the well-known cold-responsive regulators CBFs,HSFC1,ZAT6/10,and CZF1 among others.We used Arabidopsis BBX29 for experimental validation.Expression and genetic analyses showed that cold-induction of BBX29 is CBF-and abscisic acid-independent,and BBX29 is a negative regulator of cold tolerance.Integrative RNA-seq and Cleavage Under Targets and Tagmentation followed by sequencing analyses revealed that BBX29 represses a set of cold-induced TFs(ZAT12,PRR9,RVE1,MYB96,etc.).Altogether,our analysis yielded a library of eudicot CoCoFos and demonstrated that BBX29 is a negative regulator of cold tolerance in Arabidopsis.展开更多
Main observation and conclusion The reaction of 2-alkynylanisoles/sulfides with SOCl_(2) and DMSO was conducted to conveniently furnish the biologically interesting 3-(methylthio)-benzo[b]furans/thiophenes via intramo...Main observation and conclusion The reaction of 2-alkynylanisoles/sulfides with SOCl_(2) and DMSO was conducted to conveniently furnish the biologically interesting 3-(methylthio)-benzo[b]furans/thiophenes via intramolecular cyclization.DMSO acts as a solvent as well as a sulfur source and can also be replaced with DMSO-d_(6),enabling the incorporation of the SCD3 moiety of DMSO-d_(6) to the 3-position of the heterocyclic frameworks.展开更多
The reaction of pyridin-2(1H)·ones with PhlCl_(2) and NH_(4)SCN enables an efficient regioselective thiocyanation,leading to the synthesis of the biologically interesting C5 thiocyanated 2-pyridones in good to hi...The reaction of pyridin-2(1H)·ones with PhlCl_(2) and NH_(4)SCN enables an efficient regioselective thiocyanation,leading to the synthesis of the biologically interesting C5 thiocyanated 2-pyridones in good to high yields.The mechanistic pathway of this metal-free approach is postulated to involve the formation of the reactive thiocyanogen chloride from the reaction of PhlCl_(2) and NH4SCN followed with the regioselective electrophilic thiocyanation of the pyridin-2(1H)-one ring.展开更多
The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replac...The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replaced with its deuterated counterpart,enabling the method applicable to the construction of indole skeleton bearing a SCD_(3) moiety at its 3-position.展开更多
3-Thiocyanated chromones was conveniently synthesized from alkynyl aryl ketones using commercially available,inexpensive trichloroisocyanuric acid(TCCA)as oxidant and NH_(4)SCN as thiocyanato(SCN)source.This metalfree...3-Thiocyanated chromones was conveniently synthesized from alkynyl aryl ketones using commercially available,inexpensive trichloroisocyanuric acid(TCCA)as oxidant and NH_(4)SCN as thiocyanato(SCN)source.This metalfree approach is postulated to first in situ generate thiocyanogen chloride(Cl-SCN)from the reaction of TCCA and NH_(4)SCN,followed by a rare efficient electrophilic thiocyano oxyfunctionalization of alkynes enabled by the reactive electrophilic species generated thereof.展开更多
基金supported by the National Key Research and Development Program of China under Grand No.2016YFB0200902supported by the Program for Guangdong Introducing Innovative and Entrepreneurial Teams under Grant No.2016ZT06D211
文摘In this paper, wave-body interactions under the effects of complex topography are investigated numerically by a two-phase incompressible Reynolds-Averaged Navier-Stokes(RANS) solver in OpenFOAM. A submerged bottom-standing structure is distributed below the floating body, and the effects of the water depth and top width of the submerged structure on wave-body interactions are studied. The results show that the submerged structure can affect wave loads and roll motion. The vertical force can be amplified on the fixed body when the water depth of the submerged structure is smaller than half of the water depth of the body. The top width significantly affects the vertical force when the top width is smaller than the incident wave length and larger than the body width. For the free-rolling body, roll amplitude can be increased when the ratio of the incident wave length to the water depth of the submerged structure is large enough. On the resonance condition, roll amplitude is slightly reduced by the submerged structure. The effects of the top width on roll amplitude are remarkable when special conditions are fulfilled.
基金This work was supported by the Strategic Priority Research Program of Chinese Academy of Sciences[grant number XDA17010101]the National Natural Science Foundation of China[grant number 41875183]the National Key R&D Program of China[grant number 2017YFA0603504].
基金supported by the National Natural Science Foundation of China(No.12001503)the Project of Beijing Municipal Commission of Education(KM 202110015001)。
文摘Many discrete systems have more distinctive dynamical behaviors compared to continuous ones,which has led lots of researchers to investigate them.The discrete predatorprey model with two different functional responses(Holling type I and II functional responses)is discussed in this paper,which depicts a complex population relationship.The local dynamical behaviors of the interior fixed point of this system are studied.The detailed analysis reveals this system undergoes flip bifurcation and Neimark-Sacker bifurcation.Especially,we prove the existence of Marotto's chaos by analytical method.In addition,the hybrid control method is applied to control the chaos of this system.Numerical simulations are presented to support our research and demonstrate new dynamical behaviors,such as period-10,19,29,39,48 orbits and chaos in the sense of Li-Yorke.
基金supported by the National Natural Science Foundation of China(31871233)Key Scientific and Technological Grant of Zhejiang for Breeding New Agricultural Varieties(2021C02070-1)the Scientific Research Development Fund of Zhejiang A&F University(2022LFR082).
文摘C-repeat binding factors(CBFs)are well-known transcription factors(TFs)that regulate plant cold acclimation.RNA sequencing(RNA-seq)data from diverse plant species provide opportunities to identify other TFs involved in the cold response.However,this task is challenging because gene gain and loss has led to an intertwined community of co-orthologs and in-paralogs between and within species.Using orthogroup(closely related homologs)analysis,we identified 10,549 orthogroups in five representative eudicots.A phylotranscriptomic analysis of cold-treated seedlings from eudicots identified 35 high-confidence conserved cold-responsive transcription factor orthogroups(CoCoFos).These 35 CoCoFos included the well-known cold-responsive regulators CBFs,HSFC1,ZAT6/10,and CZF1 among others.We used Arabidopsis BBX29 for experimental validation.Expression and genetic analyses showed that cold-induction of BBX29 is CBF-and abscisic acid-independent,and BBX29 is a negative regulator of cold tolerance.Integrative RNA-seq and Cleavage Under Targets and Tagmentation followed by sequencing analyses revealed that BBX29 represses a set of cold-induced TFs(ZAT12,PRR9,RVE1,MYB96,etc.).Altogether,our analysis yielded a library of eudicot CoCoFos and demonstrated that BBX29 is a negative regulator of cold tolerance in Arabidopsis.
基金We acknowledge the National Natural Science Foundation of China(No.21472136)for financial support.
文摘Main observation and conclusion The reaction of 2-alkynylanisoles/sulfides with SOCl_(2) and DMSO was conducted to conveniently furnish the biologically interesting 3-(methylthio)-benzo[b]furans/thiophenes via intramolecular cyclization.DMSO acts as a solvent as well as a sulfur source and can also be replaced with DMSO-d_(6),enabling the incorporation of the SCD3 moiety of DMSO-d_(6) to the 3-position of the heterocyclic frameworks.
基金Y.Du acknowledges the National Natural Science Foundation of China(No.22071175)for financial support.
文摘The reaction of pyridin-2(1H)·ones with PhlCl_(2) and NH_(4)SCN enables an efficient regioselective thiocyanation,leading to the synthesis of the biologically interesting C5 thiocyanated 2-pyridones in good to high yields.The mechanistic pathway of this metal-free approach is postulated to involve the formation of the reactive thiocyanogen chloride from the reaction of PhlCl_(2) and NH4SCN followed with the regioselective electrophilic thiocyanation of the pyridin-2(1H)-one ring.
基金the National Natural Science Foundation of China(No.22071175)K.Zhao acknowledges the National Key R&D Program of China(No.2019YFA0905104)for financial supports.
文摘The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replaced with its deuterated counterpart,enabling the method applicable to the construction of indole skeleton bearing a SCD_(3) moiety at its 3-position.
基金We acknowledge the National Natural Science Foundation of China(No.22071175)for financial supportX.B.Wang thanks the financial support from the National Natural Science Foundation of China(Nos.21908018,22078174),and Qi Lu Young Scholar Start-up Foundation of Shandong University.
文摘3-Thiocyanated chromones was conveniently synthesized from alkynyl aryl ketones using commercially available,inexpensive trichloroisocyanuric acid(TCCA)as oxidant and NH_(4)SCN as thiocyanato(SCN)source.This metalfree approach is postulated to first in situ generate thiocyanogen chloride(Cl-SCN)from the reaction of TCCA and NH_(4)SCN,followed by a rare efficient electrophilic thiocyano oxyfunctionalization of alkynes enabled by the reactive electrophilic species generated thereof.
