Standardized Cultivation Technology of Maize Jinhai 5

It is very important to adopt standardized production technology in the process of maize cultivation,which is conducive to giving full play to the high-yield,high-quality and multi-resistant characteristics of Jinhai 5.This paper standardized the cultivation technology of Jinhai 5 from the aspects of maize seed quality,fertilization before sowing,sowing,seedling management,mid-period management,later management,disease and pest control,and harvesting,so as to provide reference for the standardized production of maize Jinhai 5.

血管介入治疗对中晚期肿瘤患者凝血功能影响的回顾性研究

目的:研究中晚期肿瘤患者血管介入治疗前后凝血功能的变化。方法:回顾性分析2018年1月至2018年10月于首都医科大学附属北京中医医院行血管介入治疗的174例中晚期肿瘤患者,观察血管介入治疗前后血小板及相关凝血指标的变化。血管介入治疗后1周内行相关指标检测的63例患者设为A组,血管介入治疗后1个月(30±7天)行相关指标检测的111例患者设为B组。数据采用SPSS 22.0软件进行统计学分析。结果:A组纤维蛋白原(FIB)、D-D二聚体(D-D)值较治疗前显著升高,活化部分凝血活酶时间(APTT)缩短,血小板(PLT)值较治疗前降低(均P<0.05);B组FIB、D-D、PLT值较治疗前降低,凝血酶原时间(PT)、APTT较治疗前延长(P>0.05);血管介入治疗前,共58例患者伴有血液高凝状态,其中A组28例(48.3%),B组30例(51.7%);血管介入治疗后,共71例(40.8%)患者伴有血液高凝状态,其中A组40例(56.3%),B组31例(43.7%)。结论:血管介入治疗在短期内可影响相关凝血指标,加剧中晚期肿瘤患者的血液高凝状态,但随着时间延长,对患者凝血功能的影响逐渐降低,相关血凝指标可逐渐恢复至治疗前水平,建议在血管介入治疗后密切监测患者凝血功能变化。

Engineering the Local Coordination Environment of Single-Atom Catalysts and Their Applications in Photocatalytic Water Splitting:A Review

Single-atom catalysts(SACs),with atomically dispersed metal atoms anchored on a typical support,representing the utmost utilization effi ciency of the atoms,have recently emerged as promising catalysts for a variety of catalytic applications.The electronic properties of the active center of SACs are highly dependent on the local environment constituted by the single metal atom and its surrounding coordination elements.Therefore,engineering the coordination environment near single metal sites,from the fi rst coordination shell to the second shell or higher,would be a rational way to design effi cient SACs with optimized electronic structure for catalytic applications.The wide range of coordination confi gurations,guaranteed by the multiple choices of the type and heterogeneity of the coordination element(N,O,P,S,etc.),further off er a large opportunity to rationally design SACs for satisfactory activities and investigate the structure-performance relationship.In this review,the coordination engineering of SACs by varying the type of coordination element was elaborated and the photocatalytic water splitting of SACs was highlighted.Finally,challenging issues related to the coordination engineering of SACs and their photocatalytic applications were discussed to call for more eff orts devoted to the further development of single-atom catalysis.

Study on the Consumer Credit Development Path of China——From the Perspective of Supply-side Reform

With the development of China's market economy,China's consumer credit has also developed rapidly,but there are also problems such as unbalanced credit structure and uneven regional development.Based on the perspective of supply-side reforms,this article analyzes the opportunities and risks of China's consumer credit development,and puts forward practical and effective suggestions for problems,which is of great significance to the promotion of the healthy development of China's consumer credit.

Structural design and thermal performance simulation of shade roof of double-slope greenhouse for mushroom-vegetable cultivation

A new type of roof structure was developed for the shade room in a double-slope greenhouse used for mushroom-vegetable planting.A simulation model was developed to evaluate the thermal performance of the new roof with an insulation thickness of 0.12 m in Beijing,China.The results showed that(1)the indoor air temperature of the shade room with the newly implemented shade roof was 2.7℃-4.9℃ higher than that of an ordinary shade room during the winter months;(2)The indoor air temperature of the solar room adjacent to the shade room with the new roof was higher than that of the ordinary solar room and the minimum indoor air temperature of the solar room was increased 1.9℃ at winter night;(3)the indoor temperature of the shade room with the new roof design was 2℃-4℃ lower than that of the ordinary shade room during the summer months;(4)Under factory production conditions,which were conducted in a controlled environment to promote the annual growth of the edible fungus,the heating energy consumption of the shade room after the implementation of the new roof structure was reduced by 69.3%,the amounted to total energy savings of 61.3% per year.The new roof structure provided a significant improvement in the thermal environment compared to an ordinary shade room,improved the vegetable growth in the winter,and also significantly reduced the energy consumption and production costs.

EFFECTS OF TRANSPORT STRESS ON THE INTESTINES INVOLVING NEURONAL NITRIC OXIDE SYNTHASE

Transport stress is commonly suffered by animals with gastrointestinal dysfunction a common symptom.Currently,the mechanisms of transport stress-induced intestine impairment are largely unknown.The aim of this study was to investigate the effects of transport stress on the expression of neuronal nitric oxide synthase(nNOS)and the distribution of nNOS-positive neurons of the intestines in rats and to explore the neuroendocrine mechanism of transport stress.In this study,Sprague Dawley rats(n=6)were subjected on a constant temperature shaker for 1(S1d)or 3 d(S3d).Rats exhibited increased serum glucose and diminished total number of leukocytes,in which lymphocytes level was also decreased in the S1d group(P<0.05).Also,normal intestinal morphology was disrupted in the S1d rats,and the thickness of muscle layers was decreased in duodenum,jejunum and colon of S3d rats.In addition,it was found that nNOS expression,as well as the number of nNOSpositive neurons in the myenteric plexus were downregulated in duodenum,jejunum and colon of S3d rats compared with that of unstressed rats(P<0.05).These data reveals that transport stress induced intestinal damage and uncovers potential action mechanisms that nNOS-positive neurons and nNOS expression might be involved in modulating this process.

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

The present study was designed to investigate the protective effects of leonurine, a compound purified from Herba Leonuri that is active on ischemic rat behavior and cortical neurons, and explore the underlying mechanism. The general rat activity, cortical neuron morphology, superoxide dismutase (SOD), malondialdehyde (MDA),γ- aminobutyric acid (GABA) and glutamate decarboxylase 67 (GAD67) levels were measured. We found leonurine significantly improve the general activity of rats in an opefield test, which was associated with attenuated neuronal damage induced by ischemia. Moreover, serum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemia group. In addition, GABA content in the cerebral cortex was significantly greater in high-dose leonurine group. Correspondingly, GAD67 protein level coincided with the GABA level. Taken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative and anti-excitotoxicity effects by targeting GABA and leonurine might become a useful adjuvant neuroprotective agent.

QcReads:An Adapter and Quality Trimming Tool for Next-Generation Sequencing Reads

With the advent of next-generation sequencing(NGS)technologies,it is possible to obtain huge amount of genome or transcriptome sequence with high coverage.NGS technologies are now extensively used in various fields such as genetics(Feuillet et al.,2011;Young et al.,2012;Ling et al.,2013)and clinical medicine(Kwon and Goate,2000;Pflueger et al.,2011;Manske et al.,2012;Xu et al.,2012;Jia et al.,2013).However,these sequencing technologies still exhibit some limitations。

Design and experiment of a barrel-shaped aeroponic cultivation system

Theoretically,aeroponic cultivation is easy to make plant roots in a better growth environment.In order to give better play to the theoretical advantages of aeroponic cultivation,further optimize the structure of the aeroponic cultivation system,and make the aeroponic cultivation system more scientific and reasonable,a barrel-shaped aeroponic cultivation system is designed.The aeroponic cultivation system is composed of a monitoring and control system,power equipment,nutrient solution storage,and treatment facility,nutrient solution supply pipelines,aeroponic cultivation barrels,and nutrient solution return pipelines.The cultivation system working principle and its technical requirements were analyzed,and its structure for meeting the requirements of large-scale production was determined.A performance test of the barrel-shaped aeroponic cultivation system using cultivated narrow leaved Chinese chives was conducted.The Chinese chives were cultivated to 6 beds of the cultivation barrel.The system supplied nutrient solution every 30 min for 2 min each time.After 5 weeks growth,the length,leaf width,and single weight of Chinese chive ranged from 293-362 mm,4.1-6.7 mm,and 3.48-5.47 g,respectively,the average length,leaf width,and single weight of Chinese chive were 327 mm,5.1 mm,and 4.24 g,respectively,and there were no significant differences in the length,leaf width,and single weight of Chinese chive on 6 beds by One-way ANOVA.The test results showed that all the Chinese chive in each bed of the cultivation barrel grew well and uniform,which indicated that the circulation process of nutrient solution supply and return in the system was normal,the process of nutrient solution atomization in the system was uniform,and the aeroponic cultivation system operated normally and stable and could be applied in production.

Oral administration of Allium sativum extract protects against infectious bursal disease in chickens

Garlic(Allium sativum,Liliaceae)has been safely used for more than 5000 years,and research on garlic extract is rapidly increasing because of its multiple biological functions.The in vivo effects of oral administration of garlic mixture(GM,water-soluble extract)on infectious bursal disease virus(IBDV)-infected specific pathogen free male white leghorn chicken were examined through histopathological,immunohistochemical,and Western blot analyses,and enzyme-linked immunosorbent assay.The results confirmed the protective effects of oral administration of 5 mg·kg^(–1) BW GM(Group GM1)on bursal lesions after IBDV infection.In particular,protein expression of IBDV in the bursa decreased in Group GM1,indicating that GM administration decreased IBDV replication in the bursa.Furthermore,immunoglobulin M-and A-bearing B lymphocytes significantly increased 7 days post infection in bursae in Group GM1(P<0.01),suggesting that the oral administration of 5 mg·kg^(–1) GM offers moderate protection against B cell destruction after IBDV infection.During infection,the concentration of bursal interferon gamma(IFN-g)increased and peaked in Group GM1 earlier than in Group T(IBDV-exposed),demonstrating that GM administration prompted the production of IFN-g to protect against IBDV infection.