Geometric active contour based approach for segmentation of high-resolution spaceborne SAR images

Segmentation is the key step in auto-interpretation of high-resolution spaceborne synthetic aperture radar（SAR） images. A novel method is proposed based on integrating the geometric active contour（GAC） and the support vector machine（SVM）models. First, the images are segmented by using SVM and textural statistics. A likelihood measurement for every pixel is derived by using the initial segmentation. The Chan-Vese model then is modified by adding two items： the likelihood and the distance between the initial segmentation and the evolving contour. Experimental results using real SAR images demonstrate the good performance of the proposed method compared to several classic GAC models.

A new way to analyze the traditional Chinese medicine syndrome:heat toxin syndrome in cerebral infarction

Objective:To establish a diagnostic system for heat toxin syndrome of acute cerebral infarction.Based on this toxin syndrome diagnostic system,the general principles of heat toxin development will be uncovered,and the critical turning point at which the heat toxin syndrome occurs will also be explored.Methods:In this study,a total of 271 hypertension patients with cerebral infarction within 72 h were recruited from the Affiliated Dongfang Hospital of the Beijing University of Chinese Medicine,the Affiliated Dongzhimen Hospital of Beijing University of Chinese Medicine,the Affiliated Renmin Hospital of Peking University,the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,the Affiliated Hospital of Changchun University of Traditional Chinese Medicine,the Affiliated Hospital of Hebei University of Traditional Chinese Medicine and China Meitan General Hospital from August,2008,to December,2009.The patients’Chinese medical information was recorded on days 1,3,5,7,and 14 during their hospitalizations.The medical records were recorded according to traditional Chinese medicine(TCM)theory and included the serum marker levels at the beginning and at the end of the trial.The time line was also analyzed.Results:The level of Hs-CRP,PAG,NSE,OX-LDL,and MMP-9 were abnormal and,were higher in CI patients compared to hypertension patients.In the study of the heat toxin diagnosis system,according to the entropy clustering results,30 combinations of the medical information can be sorted into the traditional syndromes,but 13 combinations cannot be sorted.To obtain more precise symptoms related to the heat toxins,a logistic regression equation was set up with the variables from the unsorted medical information;the dependent variables were fever and BP fluctuation.Weighted variables were obtained.MLP analysis demonstrated that the diagnosis model was stable and precise.The accuracy reached 83.82%.The ROC test showed that seven points of the diagnosis system was the best cutting point,with a sensitivity of 0.857 and a specificity of 0.955.Progressing stroke was related to heat toxin syndrome.When the turning point appeared,the combination of symptoms,such as coma,aphasia,gummy eyes,and halitosis,predicted the deterioration or recovery of CI.The heat toxin syndrome existed in every subtype of CI;however,the observed heat toxin levels were highest in PACI and lowest in LACI.Meanwhile,blood and sputum stasis syndromes transformed into heat toxicity were one source of heat toxin syndrome.Conclusion:Heat toxin syndrome,as well as qi/blood/sputum stasis,co-existed in the CI patients,and the transformation frequently appeared during the process.Three to five days after the onset of CI was the turning point,at which time several combinations of medical indicators make it possible to predict the development of CI.

Investigation of dementia awareness among stroke patients in China:A cross-sectional study

Objective:To provide guidelines for the prevention of post-stroke dementia,we investigated whether stroke patients were aware of post-stroke dementia and their level of dementia-related knowledge.Methods:Five dementia-related questions were designed.A field survey was conducted in a questionand-answer method using the designed questions.The surveys assessed 3000 stroke patients(2 weekse6 months after stroke attacks)from 14 hospitals/clinical centers in 7 provinces and cities across China.Results:Among 3000 stroke patients,80.5%had heard of dementia,39.1%knew that stroke can lead to dementia,55.7%believed dementia can be prevented,50.8%thought dementia can be cured,and only 8.8%had ever seen a doctor because of memory deterioration.Then,patients were classified into three groups,including a no cognitive impairment(NCI)group,a mild cognitive impairment(MCI)group,and a mild dementia(MD)group.Among the MCI and MD groups,only 8.7%(75/861)and 9.9%(64/649)of patients,respectively,had ever seen a doctor because of memory deterioration.According to our results,patients with a higher level of cognitive impairment had a lower awareness of dementia(P<.001).Conclusion:The awareness of dementia in stroke patients in China is low,and the consultation rate is even lower.Moreover,patients with a higher level of cognitive impairment have a lower awareness of dementia.To improve public awareness and improve prevention,more emphasis should be put on education regarding post-stroke dementia.Routine cognitive function screening should be conducted on stroke patients as an effective way to assess dementia.

基于数据挖掘的中药复方专利治疗血管性痴呆用药规律研究

目的运用数据挖掘方法分析血管性痴呆(VD)复方专利用药规律。方法检索国家知识产权局中国专利公布公告网站及中国知识资源总库(CNKI)建库至2022年3月31日发布的治疗VD的中药复方专利,采用中医传承辅助平台(V2.5)进行频次统计、聚类分析和关联分析,探讨用药规律。结果共纳入复方专利154个,涉及中药227味,应用最多的中药为石菖蒲(44次,28.57%),常用药对有丹参-石菖蒲(17次,11.03%)等,用药药性多属温,药味多属甘,归经以肝经为主;关联规则置信度较高的有“山萸肉-石菖蒲”(0.90)、“山萸肉-熟地黄”(0.90),基于复杂网络得出核心药物有“熟地黄-肉苁蓉-山萸肉”等14组,通过熵聚类分析提取新处方有“熟地黄、肉苁蓉、山萸肉、天冬”等7组。结论中药复方专利治疗VD以补益亏虚、活血化瘀、祛痰化湿、祛风通络、开窍醒神为主,可为临床实践和新药研发提供参考。

Emergence of ASEAN,China and India and the Regional Architecture

象经济力量的 ASEAN，中国和印度的上升具有到地区性以及全球的经济开发的大意义。尽管他们在全球经济的优越将继续，他们将不得不去大疼痛遇见新挑战。就象一个组的 ASEAN，中国和印度而言，由于他们在经济发展层次的差别，经济结构和政策使优先级担心，他们在全球问题的一个范围上提出一个统一位置是困难的。ASEAN，中国和印度必须促进开、透明、有效的地区性以及全球的环境。他们需要在设计建筑学保证地区性以及全球的更自由的贸易和投资和更稳定的金融，并且在未来起更活跃的作用合作全球统治和 rulemaking。

Northeast Asian Community Building: What Needs to Be Done?

The aim of the Northeast Asian community building is to create an environment for living together peacefully and for realizing prosperity through cooperation. Economically, a community will integrate regional economies and share great interests for common prosperity. Politically, a community will stabilize the region with trust and cooperation. In terms of security, a community will realize the lasting peace of the region. The three economies of China, Japan, and the ROK account for a vast majority of Northeast Asia＇s regional economy. China and the ROK are two key players in the Northeast Asian community building. China-ROK cooperation will be helpful for China-Japan relations that now appear to be in a difficult situation. Northeast Asian economic cooperation has developed into a multi-layered structure both in institutional and non-institutional ways. In order to build the Northeast Asian community, those three countries must first improve and make three close bilateral relationships. However, Northeast Asian community building should not just include China, Japan, and the ROK. The DPRK, Mongolia, and also Russia should be engaged as early as possible. Northeast Asian community is a vision and also a dream that needs great efforts to be realized by both a good spirit and real actions.