Introduction Gastrointestinal stromal tumors(GISTs)in adults are nearly 10%–30%with a potential malignant tendency[1].Colorectal GISTs account for 5%of all cases and have a higher progression risk with a poor prognos...Introduction Gastrointestinal stromal tumors(GISTs)in adults are nearly 10%–30%with a potential malignant tendency[1].Colorectal GISTs account for 5%of all cases and have a higher progression risk with a poor prognosis[2,3].Rectal GISTs usually need radical operations such as laparoscopy to obtain tumor-free margins.Sometimes,it is difficult for surgery to preserve the anal function because of the tumor size and location.Here,we report a case of a 70-year-old female with a giant GIST located in the lower rectum,which was removed by function-preserving endoscopic minimally invasive resection after routine imatinib therapy.展开更多
Endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)are useful therapeutic techniques for colorectal tumors.Currently,new techniques based on these procedures are available,such as endoscopic sub...Endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)are useful therapeutic techniques for colorectal tumors.Currently,new techniques based on these procedures are available,such as endoscopic submucosal dissection with snare(ESD-S)and endoscopic mucosal resection with pre-cutting(EMR-P).For the excision of colorectal tumors,each of these techniques has been characterized as having a high total resection rate,low recurrence rate or low complication rate.In this study,we analysed clinical trials that had recently been published,to search for the most appropriate endoscopic treatment for colorectal tumors.Our search results revealed the following:for a tumor with a diameter less than 20mm,the surgeon should choose ESD,ESD-S,EMR-P or EMR,depending on the condition of the tumor.On the other hand,to excise a tumor larger than 20mm in diameter,ESD and ESD-S should be the first choices.However,if the patient has a high risk of complications due to ESD or ESD-S,the use of EMR-P would be suitable.Because of the high possibility of canceration in a tumor larger than 20mm in diameter,EMR is not the optimal endoscopic treatment for the excision of a colorectal tumor,due to a low total resection rate and a high recurrence rate.展开更多
Introduction The cervicothoracic junction is a complex and narrow space involving many key neurovascular structures with close associations.Tumors frequently invade or compress surrounding tissues and organs in this r...Introduction The cervicothoracic junction is a complex and narrow space involving many key neurovascular structures with close associations.Tumors frequently invade or compress surrounding tissues and organs in this region,resulting in a risk of injury during surgery[1].There are many surgical approaches to treat tumors of the cervicothoracic junction,but they are associated with high morbidity and mortality[2,3].展开更多
文摘Introduction Gastrointestinal stromal tumors(GISTs)in adults are nearly 10%–30%with a potential malignant tendency[1].Colorectal GISTs account for 5%of all cases and have a higher progression risk with a poor prognosis[2,3].Rectal GISTs usually need radical operations such as laparoscopy to obtain tumor-free margins.Sometimes,it is difficult for surgery to preserve the anal function because of the tumor size and location.Here,we report a case of a 70-year-old female with a giant GIST located in the lower rectum,which was removed by function-preserving endoscopic minimally invasive resection after routine imatinib therapy.
基金The National Natural Science Foundation of China(Grant No.81101566).
文摘Endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)are useful therapeutic techniques for colorectal tumors.Currently,new techniques based on these procedures are available,such as endoscopic submucosal dissection with snare(ESD-S)and endoscopic mucosal resection with pre-cutting(EMR-P).For the excision of colorectal tumors,each of these techniques has been characterized as having a high total resection rate,low recurrence rate or low complication rate.In this study,we analysed clinical trials that had recently been published,to search for the most appropriate endoscopic treatment for colorectal tumors.Our search results revealed the following:for a tumor with a diameter less than 20mm,the surgeon should choose ESD,ESD-S,EMR-P or EMR,depending on the condition of the tumor.On the other hand,to excise a tumor larger than 20mm in diameter,ESD and ESD-S should be the first choices.However,if the patient has a high risk of complications due to ESD or ESD-S,the use of EMR-P would be suitable.Because of the high possibility of canceration in a tumor larger than 20mm in diameter,EMR is not the optimal endoscopic treatment for the excision of a colorectal tumor,due to a low total resection rate and a high recurrence rate.
基金supported by the Shanghai Municipal Commission of Science and Technology[grant number 19411951600]。
文摘Introduction The cervicothoracic junction is a complex and narrow space involving many key neurovascular structures with close associations.Tumors frequently invade or compress surrounding tissues and organs in this region,resulting in a risk of injury during surgery[1].There are many surgical approaches to treat tumors of the cervicothoracic junction,but they are associated with high morbidity and mortality[2,3].
