Regulating solid electrolyte interphase film on fluorinedoped hard carbon anode for sodium-ion battery

For the performance optimization strategies of hard carbon,heteroatom doping is an effective way to enhance the intrinsic transfer properties of sodium ions and electrons for accelerating the reaction kinetics.However,the previous work focuses mainly on the intrinsic physicochemical property changes of the material,but little attention has been paid to the resulting interfacial regulation of the electrode surface,namely the formation of solid electrolyte interphase(SEI)film.In this work,element F,which has the highest electronegativity,was chosen as the doping source to,more effectively,tune the electronic structure of the hard carbon.The effect of F-doping on the physicochemical properties of hard carbon was not only systematically analyzed but also investigated with spectroscopy,optics,and in situ characterization techniques to further verify that appropriate F-doping plays a positive role in constructing a homogenous and inorganic-rich SEI film.The experimentally demonstrated link between the electronic structure of the electrode and the SEI film properties can reframe the doping optimization strategy as well as provide a new idea for the design of electrode materials with low reduction kinetics to the electrolyte.As a result,the optimized sample with the appropriate F-doping content exhibits the best electrochemical performance with high capacity(434.53 mA h g^(-1)at 20mA g^(-1))and excellent rate capability(141 mAh g^(-1)at 400 mA g^(-1)).

Tumor cell membrane-coated continuous electrochemical sensor for GLUT1 inhibitor screening

Glucose transporter 1(GLUT1)overexpression in tumor cells is a potential target for drug therapy,but few studies have reported screening GLUT1 inhibitors from natural or synthetic compounds.With current analysis techniques,it is difficult to accurately monitor the GLUT1 inhibitory effect of drug molecules in real-time.We developed a cell membrane-based glucose sensor(CMGS)that integrated a hydrogel electrode with tumor cell membranes to monitor GLUT1 transmembrane transport and screen for GLUT1 inhibitors in traditional Chinese medicines(TCMs).CMGS is compatible with cell membranes of various origins,including different types of tumors and cell lines with GLUT1 expression knocked down by small interfering RNA or small molecules.Based on CMGS continuous monitoring technique,we investigated the glucose transport kinetics of cell membranes with varying levels of GLUT1 expression.We used CMGS to determine the GLUT1-inhibitory effects of drug monomers with similar structures from Scutellaria baicalensis and catechins families.Results were consistent with those of the cellular glucose uptake test and molecular-docking simulation.CMGS could accurately screen drug molecules in TCMs that inhibit GLUT1,providing a new strategy for studying transmembrane protein-receptor interactions.

How Does Focal Firms' Dual Embeddedness in Symbiotic Networks Influence Value Cocreation in Innovation Ecosystems?

Under the current complex and competitive economic environment,more and more firms are embedding themselves into symbiotic networks for value co-creation,since this has become a good strategy to obtain competitive advantages.Thus,it is important to examine the impacts of firms’embeddedness in symbiotic networks on value co-creation in innovation ecosystems.This study analyzes the mechanisms and contextual factors of firms’dual embeddedness(i.e.,relational and knowledge embeddedness)in symbiotic networks and how each influences value co-creation within innovation ecosystems.Using a sample of 1,972 observations,our findings show,firstly,that firms’dual embeddedness in symbiotic networks positively impacts on value co-creation in innovation ecosystems;secondly,that firms’dual embeddedness in symbiotic networks positively impacts on innovation ecosystem resilience;thirdly,that innovation ecosystem resilience mediates the relationships between firms’dual embeddedness in symbiotic networks and value co-creation in innovation ecosystems;and,fourthly,that innovative ecological environments positively moderate the relationship between firms’dual embeddedness and value co-creation in innovation ecosystems.These results not only enrich the theoretical framework concerning value co-creation within innovation ecosystems but also provide managerial suggestions for firms to efficiently enhance the degree of embeddedness in symbiotic networks and build highly resilient innovation ecosystems,thus promoting value co-creation among innovation ecosystem populations.