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Bleeding outcomes after non-emergency percutaneous coronary intervention in the very elderly 被引量:3
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作者 Vimalraj Bogana Shanmugam Dennis T Wong +3 位作者 Hashrul Rashid James D Cameron yuvaraj malaiapan Peter J Psaltis 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第10期624-631,共8页
Background Octogenarians constitute an increasing proportion of patients presenting for non-emergency percutaneous coronary intervention (PCI). Methods This study evaluated the in-hospital procedural characteristics... Background Octogenarians constitute an increasing proportion of patients presenting for non-emergency percutaneous coronary intervention (PCI). Methods This study evaluated the in-hospital procedural characteristics and outcomes, including the bleeding events of 293 octogenarians presenting between January 2010 and December 2012 for non-emergency PCI to a single large volume tertiary care Aus- tralian center. Comparisons were made with 293 consecutive patients aged less than or equal to 60 years, whose lesions were matched with the octogenarians. Results Non-ST elevation myocardial infarction was the most frequent indication for non-emergency PCI in octoge- narians. Compared to the younger cohort, they had a higher prevalence of co-morbidities and more complex coronary disease, comprising more type C and calcified lesions. Peri-procedural use of low molecular weight heparin (LMWH; 1.0% vs. 5.8%; P 〈 0.001) and glycopro- tein IIb/IIIa inhibitors (2.1% vs. 9.6%; P 〈 0.001) was lower, while femoral arterial access was used more commonly than in younger patients (80.9% vs. 67.6%; P 〈 0.001). Overall, there was a non-significant trend towards higher incidence of all bleeding events in the elderly (9.2% vs. 5.8%; P = 0.12). There was no significant difference in access site or non-access site bleeding and major or minor bleeding between the two cohorts. Sub-analysis did not reveal any significant influence on bleeding rates by the use of LMWH, glycoprotein IIb/IIIa inhibitors or femoral arterial access. In addition, there were no significant differences in the rates of in-hospital mortality, stroke or acute stent thrombosis between the two groups. Conclusions In this single center study, we did not observe significant increases in adverse in-hospital outcomes including the incidence of bleeding in octogenarians undergoing non-emergency PCI. 展开更多
关键词 BLEEDING Coronary artery disease OCTOGENARIANS Percutaneous coronary intervention
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