Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent d...Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent data in the field of tumor cell therapy in China,the patent map method was used to construct a scientific technical information analysis model.Then,the technical status of new drug research and development in this field was explored to identify technical opportunities.Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage.The technical innovation regions are mainly distributed in the east and innovative entities are enterprises.Technology hotspots are concentrated in areas such as A61P35,C12N5,and the patented technical efficacy is high.Besides,the technical research and development opportunities identified are closely related to the background in this field.To better promote the development of the industry,enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile,they should pay attention to technical efficacy analysis to identify more technical opportunities,thereby effectively guiding innovation strategic decisions.展开更多
Objective To analyze patent application status of Scutellaria Barbata industrial chain and provide some suggestions for its patent application and product development.Methods Patent data were collected through IncoPat...Objective To analyze patent application status of Scutellaria Barbata industrial chain and provide some suggestions for its patent application and product development.Methods Patent data were collected through IncoPat patent analysis system.Meanwhile,the patent analysis method combined with text mining method was adopted to analyze the situation and development trend of patent application in China’s Scutellaria Barbata industrial chain by using pie chart,bubble chart,trend chart and other visual charts to display the results.Results and Conclusion The patent application of Scutellaria Barbata in China mainly experienced three stages:Slow development,rapid development,and recession period.The number of patents is large,but the authorization rate is low.Individuals and enterprises are the main applicants for patent applications.Product development is involved in the whole industrial chain,but it basically focuses on its efficacy in downstream drugs,health food and other aspects.Therefore,government should enhance the awareness of patent protection,encourage collaborative innovation in industry-university-research to promote the combination of basic research and market application.Besides,it should provide theoretical support to tackle the problem of short board products,which can promote the transformation of scientific and technological achievements and contribute to the upgrading of Scutellaria Barbata industrial chain.展开更多
目的对比三孔法腹腔镜胆囊切除手术过程中,使用5 mm Trocar或10 mm Trocar作为主操作孔切除胆囊时,两种方式手术应用上的优势和不足,从而提高患者的治疗质量。方法收集十堰市太和医院肝胆胰外科诊疗中心2021年6月至2022年6月期间,由同...目的对比三孔法腹腔镜胆囊切除手术过程中,使用5 mm Trocar或10 mm Trocar作为主操作孔切除胆囊时,两种方式手术应用上的优势和不足,从而提高患者的治疗质量。方法收集十堰市太和医院肝胆胰外科诊疗中心2021年6月至2022年6月期间,由同一诊疗组收治的胆囊良性疾病患者共100例,其中50例使用5 mm Trocar作为主操作孔行腹腔镜胆囊切除术,设为实验组;50例使用10 mm Trocar作为主操作孔,设为对照组。分别对比实验组和对照组手术时间、术中出血量、术后胃肠道恢复情况、术后疼痛情况、术后住院时间、住院费用的差异,并进行统计学分析。结果两种腹腔镜胆囊切除术均可顺利完成。患者手术时间、术中出血量、术后胃肠道恢复情况、术后住院时间、住院费用比较,差异均无统计学意义(P>0.05)。实验组患者主操作孔伤口术后疼痛程度相较于对照组较低,且切口较小利于美容缝合,术后伤口更美观。结论三孔法腹腔镜胆囊切除手术过程中,使用5 mm Trocar作为主操作孔优于10 mm Trocar作为主操作孔,手术质量更高,有益于患者,此种术式值得推广。展开更多
文摘Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent data in the field of tumor cell therapy in China,the patent map method was used to construct a scientific technical information analysis model.Then,the technical status of new drug research and development in this field was explored to identify technical opportunities.Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage.The technical innovation regions are mainly distributed in the east and innovative entities are enterprises.Technology hotspots are concentrated in areas such as A61P35,C12N5,and the patented technical efficacy is high.Besides,the technical research and development opportunities identified are closely related to the background in this field.To better promote the development of the industry,enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile,they should pay attention to technical efficacy analysis to identify more technical opportunities,thereby effectively guiding innovation strategic decisions.
文摘Objective To analyze patent application status of Scutellaria Barbata industrial chain and provide some suggestions for its patent application and product development.Methods Patent data were collected through IncoPat patent analysis system.Meanwhile,the patent analysis method combined with text mining method was adopted to analyze the situation and development trend of patent application in China’s Scutellaria Barbata industrial chain by using pie chart,bubble chart,trend chart and other visual charts to display the results.Results and Conclusion The patent application of Scutellaria Barbata in China mainly experienced three stages:Slow development,rapid development,and recession period.The number of patents is large,but the authorization rate is low.Individuals and enterprises are the main applicants for patent applications.Product development is involved in the whole industrial chain,but it basically focuses on its efficacy in downstream drugs,health food and other aspects.Therefore,government should enhance the awareness of patent protection,encourage collaborative innovation in industry-university-research to promote the combination of basic research and market application.Besides,it should provide theoretical support to tackle the problem of short board products,which can promote the transformation of scientific and technological achievements and contribute to the upgrading of Scutellaria Barbata industrial chain.
文摘目的对比三孔法腹腔镜胆囊切除手术过程中,使用5 mm Trocar或10 mm Trocar作为主操作孔切除胆囊时,两种方式手术应用上的优势和不足,从而提高患者的治疗质量。方法收集十堰市太和医院肝胆胰外科诊疗中心2021年6月至2022年6月期间,由同一诊疗组收治的胆囊良性疾病患者共100例,其中50例使用5 mm Trocar作为主操作孔行腹腔镜胆囊切除术,设为实验组;50例使用10 mm Trocar作为主操作孔,设为对照组。分别对比实验组和对照组手术时间、术中出血量、术后胃肠道恢复情况、术后疼痛情况、术后住院时间、住院费用的差异,并进行统计学分析。结果两种腹腔镜胆囊切除术均可顺利完成。患者手术时间、术中出血量、术后胃肠道恢复情况、术后住院时间、住院费用比较,差异均无统计学意义(P>0.05)。实验组患者主操作孔伤口术后疼痛程度相较于对照组较低,且切口较小利于美容缝合,术后伤口更美观。结论三孔法腹腔镜胆囊切除手术过程中,使用5 mm Trocar作为主操作孔优于10 mm Trocar作为主操作孔,手术质量更高,有益于患者,此种术式值得推广。