分泌性中耳炎(otitis media with effusion,OME)是一种多继发于上呼吸道感染,临床以中耳积液、听力下降、耳内胀闷堵塞为特征,常伴耳痛、耳鸣的中耳非化脓性炎性疾病。该病发病机制复杂,主要与感染造成咽鼓管功能障碍,中耳出现负压有关...分泌性中耳炎(otitis media with effusion,OME)是一种多继发于上呼吸道感染,临床以中耳积液、听力下降、耳内胀闷堵塞为特征,常伴耳痛、耳鸣的中耳非化脓性炎性疾病。该病发病机制复杂,主要与感染造成咽鼓管功能障碍,中耳出现负压有关[1]。急性OME部分患者可在3个月内自愈,大约35%~50%发展成慢性OME,若症状持续、得不到有效治疗,可能造成永久性听力损伤,严重影响患者生活质量[2]。展开更多
After 50 years of oil and gas exploration in Longdong area of southwest Ordos Basin,NW China,a deep coal-formed gas field was discovered for the first time in Qingyang area.Through observation of field outcrops and co...After 50 years of oil and gas exploration in Longdong area of southwest Ordos Basin,NW China,a deep coal-formed gas field was discovered for the first time in Qingyang area.Through observation of field outcrops and core,analysis of common,cast and cathode thin sections,Ro and other geochemistry indexes,carbon isotope,electron microscope and other supporting tests and analyses,the hydrocarbon generation,reserves formation and reservoir formation characteristics of gas reservoirs at different buried depths in Yishaan slope were examined and compared.The deep gas reservoir has an average buried depth of more than 4200 m,and the main gas-bearing formation is the Member 1 of Lower Permian Shanxi Formation,which is characterized by low porosity,low permeability,low pressure and low abundance.It is believed that hydrocarbon generation in thin seam coal source rocks with high thermal evolution can form large gas fields,high-quality sandstone reservoirs with dissolved pores,intergranular pores and intercrystalline pores can still develop in late diagenetic stage under deep burial depth and high thermal evolution,and fractures improve the permeability of reservoirs.High drying coefficient of natural gas and negative carbon isotope series are typical geochemical characteristics of deep coal-formed gas.The integrated exploration and development method has been innovated,and the economic and effective development mode of gas fields of"dissecting sand body by framework vertical wells,centralized development by horizontal wells"has been formed.The discovery and successful exploration of the large gas field has provided geological basis and technical support for the construction of natural gas fields of 100 billion cubic meter scale in the southwest of the basin,and has important guidance for exploration of coal-derived gas with deep buried depth and high thermal evolution widely distributed in China.展开更多
文摘分泌性中耳炎(otitis media with effusion,OME)是一种多继发于上呼吸道感染,临床以中耳积液、听力下降、耳内胀闷堵塞为特征,常伴耳痛、耳鸣的中耳非化脓性炎性疾病。该病发病机制复杂,主要与感染造成咽鼓管功能障碍,中耳出现负压有关[1]。急性OME部分患者可在3个月内自愈,大约35%~50%发展成慢性OME,若症状持续、得不到有效治疗,可能造成永久性听力损伤,严重影响患者生活质量[2]。
基金Supported by the National Key Basic Research and Development Program(973 Program),China(2014CB239003)China National Science and Technology Major Project(2016ZX05050,2017ZX05001002).
文摘After 50 years of oil and gas exploration in Longdong area of southwest Ordos Basin,NW China,a deep coal-formed gas field was discovered for the first time in Qingyang area.Through observation of field outcrops and core,analysis of common,cast and cathode thin sections,Ro and other geochemistry indexes,carbon isotope,electron microscope and other supporting tests and analyses,the hydrocarbon generation,reserves formation and reservoir formation characteristics of gas reservoirs at different buried depths in Yishaan slope were examined and compared.The deep gas reservoir has an average buried depth of more than 4200 m,and the main gas-bearing formation is the Member 1 of Lower Permian Shanxi Formation,which is characterized by low porosity,low permeability,low pressure and low abundance.It is believed that hydrocarbon generation in thin seam coal source rocks with high thermal evolution can form large gas fields,high-quality sandstone reservoirs with dissolved pores,intergranular pores and intercrystalline pores can still develop in late diagenetic stage under deep burial depth and high thermal evolution,and fractures improve the permeability of reservoirs.High drying coefficient of natural gas and negative carbon isotope series are typical geochemical characteristics of deep coal-formed gas.The integrated exploration and development method has been innovated,and the economic and effective development mode of gas fields of"dissecting sand body by framework vertical wells,centralized development by horizontal wells"has been formed.The discovery and successful exploration of the large gas field has provided geological basis and technical support for the construction of natural gas fields of 100 billion cubic meter scale in the southwest of the basin,and has important guidance for exploration of coal-derived gas with deep buried depth and high thermal evolution widely distributed in China.
