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宁泌泰胶囊治疗Ⅲ型前列腺炎疗效研究 被引量:8
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作者 王家骥 杨建林 +2 位作者 刘跃新 张光银 陈山 《中国中西医结合外科杂志》 CAS 2018年第2期170-172,共3页
目的:评价宁泌泰胶囊治疗Ⅲ型前列腺炎的疗效和安全性。方法:采用宁泌泰胶囊自身对照的临床研究方法,共45例Ⅲ型前列腺炎患者入选,受试者口服宁泌泰胶囊,4粒/次,3次/d,4周为1疗程。以NIH-CPSI评分为主要疗效指标,评价宁泌泰胶囊治疗效果... 目的:评价宁泌泰胶囊治疗Ⅲ型前列腺炎的疗效和安全性。方法:采用宁泌泰胶囊自身对照的临床研究方法,共45例Ⅲ型前列腺炎患者入选,受试者口服宁泌泰胶囊,4粒/次,3次/d,4周为1疗程。以NIH-CPSI评分为主要疗效指标,评价宁泌泰胶囊治疗效果;用不良事件及检测治疗前后患者尿常规及肝肾功能指标评估其安全性。结果:NIH-CPSI总分治疗前为(19.31±2.18),治疗4周后下降为(12.53±6.22)(P<0.01);疼痛症状评分治疗前为(8.46±2.18),治疗2周后为(5.92±3.04)(P<0.05),治疗4周后下降为(4.45±3.90)(P<0.01)。总有效率为73%。结论:宁泌泰胶囊能明显降低Ⅲ型前列腺炎患者的NIH-CPSI评分,具有较好的疗效和临床安全性,为后期大规模临床研究奠定了良好的基础。 展开更多
关键词 前列腺炎 宁泌泰胶囊 疗效 安全性
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基于纳米材料改良酶联免疫吸附法的研究进展 被引量:2
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作者 张光胤 鲁迨 +2 位作者 邓放明 赵倩 石星波 《食品与机械》 北大核心 2020年第3期225-231,共7页
文章重点总结了近年来基于纳米材料作为传统生物酶代替物,作为比色、荧光、电化学、光热效应、表面增强拉曼散射以及化学发光的信号底物构建的改良型ELISA;对改良型ELISA发展方向以及所面临的挑战进行了分析,并展望了其应用前景。
关键词 酶联免疫吸附 信号输出 纳米 比色 荧光
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Photorefractive Spatial Dark-Soliton Stripes in LiNbO_(3):Fe Crystal and Their Application 被引量:2
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作者 zhang Guo-quan LIU Si-min +2 位作者 XU Jing-jun zhang guang-yin SUN Qian 《Chinese Physics Letters》 SCIE CAS CSCD 1996年第2期101-104,共4页
We observed the photorefractive spatial dark-soliton stripes In LiNbO3:Fe crystal,and demonsirate the planar waveguide property of refractive index proiile induced by these spatial dark-soli ton stripes.We suggest a n... We observed the photorefractive spatial dark-soliton stripes In LiNbO3:Fe crystal,and demonsirate the planar waveguide property of refractive index proiile induced by these spatial dark-soli ton stripes.We suggest a new mothed to form the planar waveguide utilizing the grating fixing technique. 展开更多
关键词 technique WAVEGUIDE PHOTOREFRACTIVE
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Domain Reversal Characteristics of Near-Stoichiometric LiNbO3 Crystals 被引量:1
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作者 姚江宏 许京军 +3 位作者 张光寅 陈晓军 李兵 李冠告 《Chinese Physics Letters》 SCIE CAS CSCD 2000年第7期513-514,共2页
The domain reversal characteristics of near-stoichiometric LiNbO3 ([Li]/[Li+Nb]=0.496) single crystals, which are grown by the Czochralski method with K2O tlux, are investigated. The switch tield for 180° ferroel... The domain reversal characteristics of near-stoichiometric LiNbO3 ([Li]/[Li+Nb]=0.496) single crystals, which are grown by the Czochralski method with K2O tlux, are investigated. The switch tield for 180° ferroelectric domain reversal in the near-stoichiometric LiNbO3 crystal is 8.0±0.5kV/mm, which is only one third of the switching field required for the congruent LiNbO3 crystals. We have successfully achieved 180° domain reversal in near-stoichiometric LiNbO3 samples of 1.0mm thickness. 展开更多
关键词 LINBO3 CRYSTAL FERROELECTRIC
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A New Method to Suppress the Fanning Noise in the Photorefractive LiNbO_(3):Fe Crystals 被引量:1
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作者 SUN Qian TIAN Guo-yun +2 位作者 LIU Si-min XU Jing-jun zhang guang-yin 《Chinese Physics Letters》 SCIE CAS CSCD 1996年第9期675-677,共3页
A new method to suppress the fanning noise caused by He-Ne laser in the cooperation with Ar+laser in photorefractive LiNbO_(3):Fe crystal was successfully realized.This method is simple and efficient.By using this met... A new method to suppress the fanning noise caused by He-Ne laser in the cooperation with Ar+laser in photorefractive LiNbO_(3):Fe crystal was successfully realized.This method is simple and efficient.By using this method,fanning-noise-free hologram can be stored in LiNbO_(3):Fecrystal. 展开更多
关键词 PHOTOREFRACTIVE CRYSTAL laser
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基于高次谐波X射线光源的三维纳米相干衍射成像技术
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作者 麻永俊 李睿晅 +10 位作者 李逵 张光银 钮津 麻云凤 柯长军 鲍捷 陈英爽 吕春 李捷 樊仲维 张晓世 《物理学报》 SCIE EI CAS CSCD 北大核心 2022年第16期168-195,共28页
相干衍射成像是近20年才发展起来的一种高分辨率计算成像技术.其原理是通过采集相干光照明时样品产生的衍射图样,使用相位恢复算法计算实现样品结构的三维(3D)成像.区别于传统成像技术,该技术具有多个显著优势:1)成像分辨率接近于照明... 相干衍射成像是近20年才发展起来的一种高分辨率计算成像技术.其原理是通过采集相干光照明时样品产生的衍射图样,使用相位恢复算法计算实现样品结构的三维(3D)成像.区别于传统成像技术,该技术具有多个显著优势:1)成像分辨率接近于照明光源波长;2)成像系统简单,无需使用成像镜头,成像系统通常由相干光源、样品和CCD组成;3)无相差、色差,极紫外光子利用率高:使用计算成像,避免了引入器件的折射、反射和吸收等效应造成的相差和色差以及光子利用效率下降.自上世纪末,基于大型相干极紫外和X射线光源的相干衍射成像技术发展迅速,已达亚纳米级分辨率.此后,随着飞秒激光高次谐波技术的成熟,相干极紫外和X射线光源的体积和成本大幅度降低,相干衍射成像技术得到进一步发展和推广.发展至今日,基于高次谐波的相干衍射成像技术已经成为一种有巨大应用潜力的纳米成像技术,为半导体材料和器件表面形貌、生物微结构及动态演化、半导体和量子器件的化学成分及浓度分布、物理或化学动态过程以及量子状态等领域的探测成像提供了一种有效的技术方案,并开始在高分辨率半导体检测领域中获得实际应用.相信不久的将来,基于高次谐波相干衍射成像技术将成为纳米量级显微成像技术的杰出代表,成为和现有的原子力、近场光学、X射线、电子以及隧道扫描等显微成像相媲美的主流技术.本文回顾了相干衍射成像及其照明光源技术的发展历程,介绍了相干衍射成像技术现状和发展趋势,然后说明高次谐波光源和相干衍射成像技术原理,最后重点介绍了几种可以利用高次谐波的高相干、短波长、短脉冲及梳状超宽谱特性的衍射成像技术:探针强度约束、反射模式、频闪照相、多模态叠层、单次曝光叠层、时间分辨多路复用叠层、角度扫描相敏成像等技术. 展开更多
关键词 高次谐波 相位恢复 相干衍射成像 反射模式成像 X射线激光 3D成像
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Light-Induced Absorption in Nominally Pure Bismuth Silicon Oxide
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作者 李飞飞 许京军 +4 位作者 孔勇发 黄辉 张光寅 杨春晖 徐玉恒 《Chinese Physics Letters》 SCIE CAS CSCD 2001年第12期1595-1597,共3页
Light-induced absorption in the nominally pure bismuth silicon oxide is investigated experimentally and the result shows that it consists of transient and persistent parts. The experimental evidence is analysed based ... Light-induced absorption in the nominally pure bismuth silicon oxide is investigated experimentally and the result shows that it consists of transient and persistent parts. The experimental evidence is analysed based on the model of three groups of trap (donor) centres. 展开更多
关键词 NOMINAL BISMUTH DONOR
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Analysis of Laser Diode Pumped Solid-State Laser Resonator by the Transform Circle Approach
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作者 宋峰 张光寅 +1 位作者 许京军 张潮波 《Chinese Physics Letters》 SCIE CAS CSCD 2000年第3期203-205,共3页
The typical laser characteristics of a laser diode pumped,solid-state laser with a Z-type resonator structure are analyzed by the transform circle approach.Laser waists change with the thennal focus length of the lasi... The typical laser characteristics of a laser diode pumped,solid-state laser with a Z-type resonator structure are analyzed by the transform circle approach.Laser waists change with the thennal focus length of the lasing medium so that the output power becomes unstable.In particular,there is a very unstable operation region when the pump power is of medium magnitude.A method is put forward to avoid this situation. 展开更多
关键词 PUMPED PUMP RESONATOR
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Measurement of Photorefractive Two-Wave Coupling Exponential Gain Coefficient of LiNbO_(3) : Fe Crystal
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作者 孙骞 李玉栋 +4 位作者 许京军 张心正 张国权 刘思敏 张光寅 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第5期348-350,共3页
For a photorefractive crystal,the exponential gain coefficient of two-wave coupling,Г,is a constant.In this paper,the constantГof a LiNbO_(3):Fe crystal is measured by using Gaussian beams and quasi-uniform beams.Th... For a photorefractive crystal,the exponential gain coefficient of two-wave coupling,Г,is a constant.In this paper,the constantГof a LiNbO_(3):Fe crystal is measured by using Gaussian beams and quasi-uniform beams.The difference between the results is attributed to the self-defocusing effect of the crystal. 展开更多
关键词 CRYSTAL attributed EXPONENTIAL
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Valence and Electronic Shell Configuration Characters of Damage-Resistant Dopants in LiNbO_(3) Crystals
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作者 张国权 张光寅 +3 位作者 刘思敏 许京军 孙骞 刘建军 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第9期686-688,共3页
We analyze the valence and electronic shell configuration characters of all damage-resistant dopants found in LiNbO_(3) crystals up to now.We show that all damage-resistant dopants have only one valence state.We also ... We analyze the valence and electronic shell configuration characters of all damage-resistant dopants found in LiNbO_(3) crystals up to now.We show that all damage-resistant dopants have only one valence state.We also show that the electronic shell configurations of these damage-resistant ions are filled fully,as are the cases of the inert elements.from this point of view,we conclude that the anti-site NbLi should be involved in the charge transport process,while the Li vacancy VLi is not involved in the charge transport process.It also can give us some insights about how to select a damage-resistant dopant for LiNbO_(3) crystal. 展开更多
关键词 process. VALENCE CONFIGURATION
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Modulated Transmission Property of Bacteriorhodopsin Film and Its Application on Thresholding Operation
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作者 李玉栋 孙骞 +6 位作者 张春平 鲁锐 富光华 张光寅 SONG Q.Wang Bruce Parsons Robert R.Birge 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第11期799-801,共3页
In this paper,the modulated transmission property of bacteriorhodopsin(bR)film is analyzed theoretically when two beams of light,yellow light and purple light,illuminate the bR film simultaneously.By using the transmi... In this paper,the modulated transmission property of bacteriorhodopsin(bR)film is analyzed theoretically when two beams of light,yellow light and purple light,illuminate the bR film simultaneously.By using the transmission property of bR film,the winner-take-all thresholding operation can be realized. 展开更多
关键词 FILM PROPERTY YELLOW
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Light Amplification in Non-photorefractive Doped Polymer Film at Red Light Wavelength
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作者 许京军 方淇音 +7 位作者 马超力 张光寅 孙骞 张国权 刘思敏 田国云 吴强 陈晓波 《Chinese Physics Letters》 SCIE CAS CSCD 1997年第3期179-182,共4页
Experimental studies of light amplification with dynamic multiwave gratings recorded in an acceptor-donor-substituted azobenzene-doped poly(methyl methacrylate)thin film by multi-wave mixing are reported.The amplifica... Experimental studies of light amplification with dynamic multiwave gratings recorded in an acceptor-donor-substituted azobenzene-doped poly(methyl methacrylate)thin film by multi-wave mixing are reported.The amplification gain was measured to be as high as 6.7,and the operation at red light wavelength decreases the absorption losses. 展开更多
关键词 DONOR MIXING FILM
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A Self-Excitation Double Pathway Relaxation Oscillational Model of Rare-Earth-Doped Laser
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作者 WANG Zhong-he zhang guang-yin 《Chinese Physics Letters》 SCIE CAS CSCD 1996年第4期281-284,共4页
A self-excitation double pathway relaxation oscillation mechanism to deal with the seif-pulsing output of up conversion laser with rare-earth ions as the active material is raised.The reabsorption of the laser signal,... A self-excitation double pathway relaxation oscillation mechanism to deal with the seif-pulsing output of up conversion laser with rare-earth ions as the active material is raised.The reabsorption of the laser signal,which causes self-excitation of system and two-pathway transition of systepi,plays a role of adjusting Q,and causes the oscillation output of laser.A qualitative analysis to the appearance of self-pulsing output of rare-earth-doped laser is given. 展开更多
关键词 OSCILLATION EXCITATION RARE
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Electron-Phonon Interaction in Small Systems
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作者 WANG Zhong-he zhang Cun-zhou zhang guang-yin 《Chinese Physics Letters》 SCIE CAS CSCD 1996年第12期919-922,共4页
The effects of electron-phonon interaction have to be taken into account for the physical process in a small system of condensed matters.The electron-phonon interaction in a I-D finite lattice system has been analyzed... The effects of electron-phonon interaction have to be taken into account for the physical process in a small system of condensed matters.The electron-phonon interaction in a I-D finite lattice system has been analyzed.The relation between the electron-phonon interaction and the symmetric properties of electronic states and phonons are considered,the transition probabilities are discussed. 展开更多
关键词 PHONON INTERACTION SYSTEM
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OBSERVATION AND ANALYSIS OF THE ACCUMULATION LINES OF SPACE CHARGES IN α-LiIO_(3) UNDER A DC ELECTRIC FIELD ALONG C-AXIS
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作者 zhang guang-yin LIU Jian FENG Shang-ting 《Chinese Physics Letters》 SCIE CAS 1985年第2期83-86,共4页
We have observed the granular deposition of metallic Li on theα-LiIO_(3) surface in contact with the cathode of DC field by a scanning electron microscope.The relationship between the accumulation lines of space char... We have observed the granular deposition of metallic Li on theα-LiIO_(3) surface in contact with the cathode of DC field by a scanning electron microscope.The relationship between the accumulation lines of space charges und the ionic transportation along c-axis is discussed. 展开更多
关键词 SPACE (3) METALLIC
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宁泌泰胶囊治疗Ⅲ型前列腺炎随机双盲安慰剂对照临床研究 被引量:23
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作者 杨建林 刘跃新 +2 位作者 张光银 陈山 张琨 《中草药》 CAS CSCD 北大核心 2019年第10期2428-2432,共5页
目的评价宁泌泰胶囊治疗Ⅲ型前列腺炎的有效性和安全性。方法采用随机、双盲以及安慰剂作为对照进行临床试验设计。试验共50例Ⅲ型前列腺炎患者入选,治疗组25例患者口服宁泌泰胶囊,每次4粒,每日3次,4周为1个疗程。对照组25例患者口服安... 目的评价宁泌泰胶囊治疗Ⅲ型前列腺炎的有效性和安全性。方法采用随机、双盲以及安慰剂作为对照进行临床试验设计。试验共50例Ⅲ型前列腺炎患者入选,治疗组25例患者口服宁泌泰胶囊,每次4粒,每日3次,4周为1个疗程。对照组25例患者口服安慰剂胶囊,用法用量与治疗组完全一致。治疗有效性以美国国立卫生院前列腺炎症状评分(NIH-CPSI)为主要疗效评价指标;以治疗前后患者尿常规及肝肾功能指标评估其安全性;并记录不良事件。结果治疗组NIH-CPSI总分治疗前为23.96±1.30,经4周治疗后下降为16.04±1.66(P<0.001)。安慰剂组与其不同,同治疗前相比,所有评分在4周治疗后无统计学差异(P>0.05)。治疗组疼痛评分、排尿评分、生活质量评分均显著性降低(P<0.05)。参与本研究完成治疗的全部患者未见明显不良反应发生。结论宁泌泰胶囊治疗Ⅲ型前列腺炎安全有效。 展开更多
关键词 宁泌泰胶囊 Ⅲ型前列腺炎 临床研究 NIH-CPSI评分 安慰剂
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