In addition to the performance of the respiratory system,COVID-19 can also have different degrees of abnormal liver function,and even liver injury and liver failure may occur in serious cases.In addition,infection wit...In addition to the performance of the respiratory system,COVID-19 can also have different degrees of abnormal liver function,and even liver injury and liver failure may occur in serious cases.In addition,infection with novel coronavirus will aggravate the liver damage of patients with chronic liver disease,resulting in a significant increase in severe morbidity and mortality.Based on this,this paper briefly reviews the mechanism of liver injury caused by COVID-19 and its impact on patients with chronic liver disease,in order to provide a theoretical basis for the prevention and treatment of COVID-19.展开更多
Novel coronavirus(SARS‑CoV‑2,SARS‑CoV‑2 for short)infection can cause a series of gastrointestinal damage.Related studies have reported that SARS‑CoV‑2 infection can lead to the occurrence and progression of ulcerativ...Novel coronavirus(SARS‑CoV‑2,SARS‑CoV‑2 for short)infection can cause a series of gastrointestinal damage.Related studies have reported that SARS‑CoV‑2 infection can lead to the occurrence and progression of ulcerative colitis,which may be related to the cytokine storm caused by SARS‑CoV‑2 infection.Recently,we have also paid attention to whether infection with SARS‑CoV‑2 will aggravate the condition of UC patients receiving biological immunotherapy and whether vaccination with SARS‑CoV‑2 is safe and effective for these patients.At present,the interaction mechanism between SARS‑CoV‑2,SARS‑CoV‑2 vaccine and ulcerative colitis is not fully understood,and more research is needed to further clarify the relationship.展开更多
Since the outbreak of COVID-19,severe acute respiratory syndrome coronavirus 2 genome is still mutating,forming a variety of variants with strong transmission capacity,causing the spread of the epidemic worldwide,posi...Since the outbreak of COVID-19,severe acute respiratory syndrome coronavirus 2 genome is still mutating,forming a variety of variants with strong transmission capacity,causing the spread of the epidemic worldwide,posing a serious threat to people's physical and mental health,and posing a major challenge to global public health.Omicron remains the main variant in several outbreaks worldwide,accounting for about 99%of the global genetic sequence.Recently,the World Health Organization announced that the subvariant of Omicron BA.5 has been found in more than 100 countries and regions around the world,causing the global epidemic rebound.However,there are few studies on the subvariant BA.5.This article reviews the latest research progress in epidemiology,infectivity,pathogenicity,vaccine and monoclonal antibody protection against Omicron subvariant BA.5,in order to provide reference for scientific prevention and control of Omicron subvariant BA.5.展开更多
基金COVID-19 Foundation Project of 940 Hospital(No.20yjky020)Huoshenshan Hospital Scientific Research Fund Project(No.HSS-217)+1 种基金Gansu Non-Infectious liver Disease Clinical Research Center(No.21JR7RA017)Clinical Liver Disease Diagnosis and Treatment Center(No.2021yxky079)。
文摘In addition to the performance of the respiratory system,COVID-19 can also have different degrees of abnormal liver function,and even liver injury and liver failure may occur in serious cases.In addition,infection with novel coronavirus will aggravate the liver damage of patients with chronic liver disease,resulting in a significant increase in severe morbidity and mortality.Based on this,this paper briefly reviews the mechanism of liver injury caused by COVID-19 and its impact on patients with chronic liver disease,in order to provide a theoretical basis for the prevention and treatment of COVID-19.
基金In‑Hospital Fund Project of No.940 Hospital(NO.20yjky020)General Research Fund Project of Huoshenshan Hospital(NO.HSS‑217)Gansu Provincial Science and Technology Department Social Development Department Clinical Medicine Research Center Project(NO.21JR7RA017)。
文摘Novel coronavirus(SARS‑CoV‑2,SARS‑CoV‑2 for short)infection can cause a series of gastrointestinal damage.Related studies have reported that SARS‑CoV‑2 infection can lead to the occurrence and progression of ulcerative colitis,which may be related to the cytokine storm caused by SARS‑CoV‑2 infection.Recently,we have also paid attention to whether infection with SARS‑CoV‑2 will aggravate the condition of UC patients receiving biological immunotherapy and whether vaccination with SARS‑CoV‑2 is safe and effective for these patients.At present,the interaction mechanism between SARS‑CoV‑2,SARS‑CoV‑2 vaccine and ulcerative colitis is not fully understood,and more research is needed to further clarify the relationship.
基金COVID-19 Emergency Medical Research Project of 940 Hospital(No.20yjky020)General Project of Huoshenshan Hospital Scientific Research Fund(No.HSS-217)。
文摘Since the outbreak of COVID-19,severe acute respiratory syndrome coronavirus 2 genome is still mutating,forming a variety of variants with strong transmission capacity,causing the spread of the epidemic worldwide,posing a serious threat to people's physical and mental health,and posing a major challenge to global public health.Omicron remains the main variant in several outbreaks worldwide,accounting for about 99%of the global genetic sequence.Recently,the World Health Organization announced that the subvariant of Omicron BA.5 has been found in more than 100 countries and regions around the world,causing the global epidemic rebound.However,there are few studies on the subvariant BA.5.This article reviews the latest research progress in epidemiology,infectivity,pathogenicity,vaccine and monoclonal antibody protection against Omicron subvariant BA.5,in order to provide reference for scientific prevention and control of Omicron subvariant BA.5.
