Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease in Asia.Several studies have shown that NAFLD is associated with obesity,insulin resistance,type 2 diabetes,hypertension,hyperlipidemia,and meta...Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease in Asia.Several studies have shown that NAFLD is associated with obesity,insulin resistance,type 2 diabetes,hypertension,hyperlipidemia,and metabolic syndrome(MS)[1].Several studies concluded that indicators such as body mass index(BMI),waist circumference(WC)。展开更多
Objective The study aims to predict 10-year cardiovascular disease(CVD)risk and explore its association with sleep duration among Chinese urban adults.Methods We analyzed part of the baseline data of a cohort that rec...Objective The study aims to predict 10-year cardiovascular disease(CVD)risk and explore its association with sleep duration among Chinese urban adults.Methods We analyzed part of the baseline data of a cohort that recruited adults for health screening by cluster sampling.The simplified Pittsburgh Sleep Quality Index(PSQI)and Framingham 10-year risk score(FRS)were used to measure sleep duration and CVD risk.Demographic characteristics,personal history of chronic diseases,lifestyle factors were collected using a questionnaire.Height,weight,total cholesterol(TC),and high-density lipoprotein cholesterol(HDL-C)were also measured.Multiple logistic regression models were performed to explore the association of sleep duration with the predicted CVD risk.Results We included 31,135 participants(median age 44 years,53.02%males)free of CVD,cerebral stroke,and not taking lipid-lowering agents.Overall,14.05%,and 25.55%of participants were at medium and high predicted CVD risk,respectively.Short sleep was independently associated with increased odds of medium to high risk of predicted 10-year CVD among males(OR=1.10;95%CI:1.01–1.19)and increased odds of medium to high and high risk of predicted 10-year CVD among females(OR=1.23;95%CI:1.08–1.40;OR=1.27;95%CI:1.11–1.44).In contrast,long sleep had no association with cardiovascular risk.Conclusion A substantial number of adults free of CVD were at high 10-year CVD risk.Short sleep was associated with increased odds of predicted CVD risk.展开更多
基金the National Key R&D Program of China[2016YFC0900600/2016YFC0900604]The Capital Health Development Special Fund,Health Management Cohort Study Based on Beijing Health Checkup Data[2018-1-2241]Database source:China Cohort Consortium,the Beijing Health Management Cohort Study[CCC2018050804]。
文摘Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease in Asia.Several studies have shown that NAFLD is associated with obesity,insulin resistance,type 2 diabetes,hypertension,hyperlipidemia,and metabolic syndrome(MS)[1].Several studies concluded that indicators such as body mass index(BMI),waist circumference(WC)。
基金the National Key R&D Program in the Thirteenth Five-year Plan from the Chinese Ministry of Science and Technology[No.2016YFC0900600,2016YFC0900604]。
文摘Objective The study aims to predict 10-year cardiovascular disease(CVD)risk and explore its association with sleep duration among Chinese urban adults.Methods We analyzed part of the baseline data of a cohort that recruited adults for health screening by cluster sampling.The simplified Pittsburgh Sleep Quality Index(PSQI)and Framingham 10-year risk score(FRS)were used to measure sleep duration and CVD risk.Demographic characteristics,personal history of chronic diseases,lifestyle factors were collected using a questionnaire.Height,weight,total cholesterol(TC),and high-density lipoprotein cholesterol(HDL-C)were also measured.Multiple logistic regression models were performed to explore the association of sleep duration with the predicted CVD risk.Results We included 31,135 participants(median age 44 years,53.02%males)free of CVD,cerebral stroke,and not taking lipid-lowering agents.Overall,14.05%,and 25.55%of participants were at medium and high predicted CVD risk,respectively.Short sleep was independently associated with increased odds of medium to high risk of predicted 10-year CVD among males(OR=1.10;95%CI:1.01–1.19)and increased odds of medium to high and high risk of predicted 10-year CVD among females(OR=1.23;95%CI:1.08–1.40;OR=1.27;95%CI:1.11–1.44).In contrast,long sleep had no association with cardiovascular risk.Conclusion A substantial number of adults free of CVD were at high 10-year CVD risk.Short sleep was associated with increased odds of predicted CVD risk.
