Aluminum alloy tubes were prepared by tube spinning.The intergranular and electrochemical corrosion tests were used to investigate the intergranular corrosion behavior of the 5A06 aluminum alloy blank sample and the s...Aluminum alloy tubes were prepared by tube spinning.The intergranular and electrochemical corrosion tests were used to investigate the intergranular corrosion behavior of the 5A06 aluminum alloy blank sample and the spinning sample.Results showed that the intergranular corrosion resistance of the spinning sample was higher than that of the blank sample.In addition,the electrochemical corrosion resistance of the spinning sample was higher than that of the blank sample.The EDS maps indicated a uniform element distribution pattern of aluminum and magnesium.Moreover,the phase composition and lattice constant of the samples were obtained by XRD analysis.The differences in microstructure between the aluminum alloy subjected to the spinning process and the untreated aluminum alloy were determined by EBSD.The differences were mainly attributed to the complex interactions among grain size,dislocations and grain boundaries.展开更多
目的对湖南汉族人群20个常染色体短串联重复序列(short tandem repeat,STR)基因座的等位基因分布、群体遗传学参数和邻近群体的遗传分析进行研究,评估其在法医学中的应用价值。方法应用Power-Plex21^(■) 试剂盒对2997例湖南汉族无关个...目的对湖南汉族人群20个常染色体短串联重复序列(short tandem repeat,STR)基因座的等位基因分布、群体遗传学参数和邻近群体的遗传分析进行研究,评估其在法医学中的应用价值。方法应用Power-Plex21^(■) 试剂盒对2997例湖南汉族无关个体进行20个STR基因座复合扩增及等位基因分型,统计等位基因频率及群体遗传学参数,计算湖南汉族与已公开报道的13个群体间的Nei’s遗传距离,进行多维尺度分析并构建系统发生树。结果20个常染色体STR基因座的杂合度为0.6009~0.9116,个人识别能力为0.7745~0.9866,三联体非父排除率为0.2920~0.8191,二联体非父排除率为0.1910~0.7086,多态信息含量为0.5348~0.9093,基因型分布符合Hardy-Weinberg平衡。20个基因座的累积个体识别率为1-1.3509×10^(-21),三联体非父累积排除率与二联体非父累积排除率分别为0.999996523945999、0.999999996129773,基于湖南汉族人群与其他13个群体间遗传距离获得的多维尺度分析及系统发生树结果显示,其与湖北汉族相距较近,而与云南苗族最远。结论20个常染色体STR基因座在湖南汉族人群中呈高度多态性和良好的鉴别能力,能为该地区法医学个体识别、亲权鉴定和群体学研究提供基础数据。展开更多
The host-guest interaction between cucurbit[8]uril（Q[8]） and chrysin（CHR） has been studied by means of 1H NMR, mass spectrometry（MS）, differential thermal analysis（DTA）, and UV-Vis spectrophotometry. The resul...The host-guest interaction between cucurbit[8]uril（Q[8]） and chrysin（CHR） has been studied by means of 1H NMR, mass spectrometry（MS）, differential thermal analysis（DTA）, and UV-Vis spectrophotometry. The results show that CHR forms a 1：1 inclusion complex with Q[8], with a binding constant of CHR with Q[8] by UV absorp- tion being 5.4 × 106. Phase solubility experiments show a 5.13-fold increase in the solubility of CHR through interac- tion with Q[8] {c（Q[8]）=10-4 real/L}. A study of the evolution of UV absorption spectra with time shows that Q[8] significantly increases the stability of CHR. The antioxidant activity of CHR-Q[8] has been tested by the ABTS me- thod. The CHR-Q[8] inclusion complex shows a better scavenging effect towards the ABTS radical than CHR, with respective IC50 values of 1.05 ×10-6 and 3.07× 10-6 mol/L. In vitro release studies have shown that CHR-Q[8] has a sustained release effcct.展开更多
The interaction between cucurbit[8]uril(Q[8])and oroxin B(ORB)was investigated by UV-visible(UV-Vis)spectroscopy,isothennal titration calorimetry(ITC),mass spectnim(MS)and nuclear magnetic resonance(NMR)spectroscopy.T...The interaction between cucurbit[8]uril(Q[8])and oroxin B(ORB)was investigated by UV-visible(UV-Vis)spectroscopy,isothennal titration calorimetry(ITC),mass spectnim(MS)and nuclear magnetic resonance(NMR)spectroscopy.The results showed that ORB formed a 2:1 inclusion complex with Q[8]with a binding constant of 8.266×10^5L^2·mol^-2.ORB had good scavenging ability for 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonate)(ABTS)tree radicals(IC50=5.74μmol/L)and the addition of Q[8]did not significantly affect the antioxidant activity of ORB(IC50=5.76μmol/L).A phase solubility experiment revealed a 1.86-fold increase in the solubility of ORB when c(Q[8])=100μmol/L.bi vitro dmg release experiments showed that the release rate for ORB@Q[8]complex was lower than that of ORB in artificial intestinal juice,and higher than that of ORB in artificial gastric juice.展开更多
基金Funded by the National Natural Science Foundation of China(No.51802189)the Shanghai Lingang Innovation Program(No.SH-LG-GK-2020-28)。
文摘Aluminum alloy tubes were prepared by tube spinning.The intergranular and electrochemical corrosion tests were used to investigate the intergranular corrosion behavior of the 5A06 aluminum alloy blank sample and the spinning sample.Results showed that the intergranular corrosion resistance of the spinning sample was higher than that of the blank sample.In addition,the electrochemical corrosion resistance of the spinning sample was higher than that of the blank sample.The EDS maps indicated a uniform element distribution pattern of aluminum and magnesium.Moreover,the phase composition and lattice constant of the samples were obtained by XRD analysis.The differences in microstructure between the aluminum alloy subjected to the spinning process and the untreated aluminum alloy were determined by EBSD.The differences were mainly attributed to the complex interactions among grain size,dislocations and grain boundaries.
文摘目的对湖南汉族人群20个常染色体短串联重复序列(short tandem repeat,STR)基因座的等位基因分布、群体遗传学参数和邻近群体的遗传分析进行研究,评估其在法医学中的应用价值。方法应用Power-Plex21^(■) 试剂盒对2997例湖南汉族无关个体进行20个STR基因座复合扩增及等位基因分型,统计等位基因频率及群体遗传学参数,计算湖南汉族与已公开报道的13个群体间的Nei’s遗传距离,进行多维尺度分析并构建系统发生树。结果20个常染色体STR基因座的杂合度为0.6009~0.9116,个人识别能力为0.7745~0.9866,三联体非父排除率为0.2920~0.8191,二联体非父排除率为0.1910~0.7086,多态信息含量为0.5348~0.9093,基因型分布符合Hardy-Weinberg平衡。20个基因座的累积个体识别率为1-1.3509×10^(-21),三联体非父累积排除率与二联体非父累积排除率分别为0.999996523945999、0.999999996129773,基于湖南汉族人群与其他13个群体间遗传距离获得的多维尺度分析及系统发生树结果显示,其与湖北汉族相距较近,而与云南苗族最远。结论20个常染色体STR基因座在湖南汉族人群中呈高度多态性和良好的鉴别能力,能为该地区法医学个体识别、亲权鉴定和群体学研究提供基础数据。
基金Supported by the National Natural Science Foundation of China（No.21272045）.
文摘The host-guest interaction between cucurbit[8]uril（Q[8]） and chrysin（CHR） has been studied by means of 1H NMR, mass spectrometry（MS）, differential thermal analysis（DTA）, and UV-Vis spectrophotometry. The results show that CHR forms a 1：1 inclusion complex with Q[8], with a binding constant of CHR with Q[8] by UV absorp- tion being 5.4 × 106. Phase solubility experiments show a 5.13-fold increase in the solubility of CHR through interac- tion with Q[8] {c（Q[8]）=10-4 real/L}. A study of the evolution of UV absorption spectra with time shows that Q[8] significantly increases the stability of CHR. The antioxidant activity of CHR-Q[8] has been tested by the ABTS me- thod. The CHR-Q[8] inclusion complex shows a better scavenging effect towards the ABTS radical than CHR, with respective IC50 values of 1.05 ×10-6 and 3.07× 10-6 mol/L. In vitro release studies have shown that CHR-Q[8] has a sustained release effcct.
文摘The interaction between cucurbit[8]uril(Q[8])and oroxin B(ORB)was investigated by UV-visible(UV-Vis)spectroscopy,isothennal titration calorimetry(ITC),mass spectnim(MS)and nuclear magnetic resonance(NMR)spectroscopy.The results showed that ORB formed a 2:1 inclusion complex with Q[8]with a binding constant of 8.266×10^5L^2·mol^-2.ORB had good scavenging ability for 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonate)(ABTS)tree radicals(IC50=5.74μmol/L)and the addition of Q[8]did not significantly affect the antioxidant activity of ORB(IC50=5.76μmol/L).A phase solubility experiment revealed a 1.86-fold increase in the solubility of ORB when c(Q[8])=100μmol/L.bi vitro dmg release experiments showed that the release rate for ORB@Q[8]complex was lower than that of ORB in artificial intestinal juice,and higher than that of ORB in artificial gastric juice.
