论中国式现代化的强国主题

现代化都以强国为目标,追求国家现代化,但不同类型的现代化追求的是不同的强国目标。与西方现代化追求的“强国”不同,在中国式现代化的目标体系中,全面建成社会主义现代化强国居于核心地位,集中体现了中国式现代化的文明主题,呈现出富强民主文明和谐美丽的基本样态。作为衡量和评价社会主义现代化强国的综合标准,“综合国力和国际影响力领先”具体体现为“五个文明”的全面提升,其着力点是“实现国家治理体系和治理能力现代化”、落脚点是“全体人民共同富裕基本实现”“人民将享有更加幸福安康的生活”。以中国式现代化推动“五个文明”的全面提升,实现“综合国力和国际影响力领先”,是一个总体性的任务,是一个系统工程,需要统筹兼顾、系统谋划、整体推进。在这个过程中,必须坚持党的全面领导、构建现代化产业体系、增强自主创新能力、大力提升文化软实力等四个核心要素或关键要素。

基于等距随机游走图的三维动态曲面对准

为了提高三维动态曲面在噪声和遮挡下的对准精度,提出时空等距随机游走图算法.该算法根据相邻两帧采样点的乘积空间定义图节点,通过时空相邻性进行节点裁剪处理.以测地距离定义图边约束,将等距映射转化为图稳定性节点选择的随机游走问题.通过马尔可夫链理论,计算得到最终的对应结果.通过对不同动态曲面数据库的实验分析表明,该算法针对具有明显噪声和空洞的三维动态曲面能够得到一致性对准关系,性能优于已有算法.

Analysis on Genetic Similarity of Japonica Rice Variety from Different Origins of Geography in the World

The genetic similarity and genetic difference among improved japonica rice varieties from different countries （or regions and organizations） were detected. The aim is to provide genetic basis to the breeding of japonica rice varieties. The genetic similarity and cluster of 313 improved japonica varieties from 20 countries （or regions and organizations） were analyzed using the SSR marker. With 34 SSR primers which were polymorphic and uniformly distributed in rice genome, totally 198 alleles were detected among these improved varieties with the average number of alleles per pair of primers of 5.8235. RM320, RM531, RM1, RM21, and RM336 located more alleles, which were 16, 13, 12, 10, and 10 respectively. RM320, RM336, RM286, RM531, and RM21 showed higher genetic diversity indexes, which were 2.3668, 2.0041, 1.9684, 1.9508, and 1.7203, respectively. The genetic similarity for improved japonica varieties among different countries （or regions and organizations） were ranged from 0.279 to 0.918, and the mean value was 0.653. The rice varieties from countries whose latitude and geography position were all nearer were clustered together with higher genetic similarity indexes. The rice varieties from countries who had more different latitude and far geography position were clustered separately with lower genetic similarity indexes. The results indicated the genetic similarity indexes among improved japonica varieties had a close relationship with the geographical position, especially with the latitude.

Implementing VLPR systems based on TMS320DM642

This paper gives a practical schema for using DSP boards to construct Vehicle License Plate Recognition (VLPR) modules that could be embedded in any Intelligent Transportation System (ITS). Using DSP can avoid the heavy investment in dedicated VLPR system and improve the computational power compared to PC software environment. Low cost, high computational power, and high flexibility of DSP provide the License Plate Recognition System (LPRS) an excellent cost-effective solution to execute the major part of the recognition tasks. This paper describes a successful implementation of VLPR system based on Texas Instruments (TI)'s TMS320DM642. The DSP board acquires video (which could be output to a monitor for surveillance) from a camera, captures images from the video, locates and recognizes the license plates in images, and then sends the recognized results and related images after compression to a host PC through the network. Finally, the overall software is optimized according to the features of DM642 chip. Experiments showed that the DSP VLPR system performs well on the local license plates, and that the processing speed and accuracy can meet the requirement of practical applications.

Adaptive foreground and shadow segmentation using hidden conditional random fields

Video object segmentation is important for video surveillance, object tracking, video object recognition and video editing. An adaptive video segmentation algorithm based on hidden conditional random fields (HCRFs) is proposed, which models spatio-temporal constraints of video sequence. In order to improve the segmentation quality, the weights of spatio-temporal con- straints are adaptively updated by on-line learning for HCRFs. Shadows are the factors affecting segmentation quality. To separate foreground objects from the shadows they cast, linear transform for Gaussian distribution of the background is adopted to model the shadow. The experimental results demonstrated that the error ratio of our algorithm is reduced by 23% and 19% respectively, compared with the Gaussian mixture model (GMM) and spatio-temporal Markov random fields (MRFs).

QTL Analysis of Some Agronomic Traits in Rice Under Different Growing Environments

The culm length, panicle length, spikelets per panicle and panicle exsertion were evaluated by using F2：3 population including 200 lines derived from the cross of indica and japonica Milyang 23/Jileng 1 under five different environments of Beijing （natural normal growing environment）, Kunming （natural cold environment）, Gongzhuling of China （cold water irrigation） and Chuncheon of Korea （natural normal growing environment and cold water irrigation）, and QTLs of these traits were analyzed by using SSR markers. The results showed that 44 QTLs related to these agronomic traits were detected under five different growing environments, and these QTLs have been located on 11 chromosomes except chromosome 9. The QTLs for qCLla, qCL1b, qCL5a, qCL6b, qPLla, qPL3a, qPL6b, qPL6c, qPL7b, qSP8b, qSPlc, qSP11a, qSP12, and qPE1 have been detected under more than two growing environments, and those that were little affected by environments, were stable QTLs. Among them, qCLla, qCLlb, qPLla, qSPlc, and qPE1 explained 24.2-55.2%, 22.7-39.9%, 12.5-27.7%, 14.4-33.5%, and 26.6-28.7% of observed phynotypic variation, respectively, which were major genes mainly appearing as overdominance. These QTLs cause the increase in action to culm length, panicle length, spikelets per panicle, and panicle exsertion under cold environment, showing that these QTLs were correlated with cold tolerance.

Analysis of Genetic Similarity for Improved Japonica Rice Varieties from Different Provinces and Cities in China

To provide a genetic basis for japonica rice breeding, the genetic similarity and cluster of 139 accessions of improved japonica rice varieties from 12 provinces and cities of China were analyzed using 34 SSR markers. Totally 198 alleles were detected among these improved japonica rice varieties with the average number of alleles per pair of primers was 5.3235. RM320, RM531, RM1, RM286, and RM336 showed more alleles, which were 15, 12, 11, 9, and 9, respectively. RM320, RM336, RM286 and RM531 showed higher genetic diversity indexes; which were 2.3324, 2.0292, 1.8996, and 1.7820, respectively. The range of genetic similar index among improved japonica rice varieties from different provinces was from 0.321 to 0.914, with the average of 0.686. There was a high genetic similarity among improved japonica rice varieties from Heilongjiang, Jilin, Liaoning, Ningxia, and Yunnan, which were located in similar latitude or similar ecological environment, while there was a low genetic similarity between improved japonica rice varieties from Guizhou and Jiangsu, and other provinces which were located in more different latitudes and ecological environments. The markers of RM320, RM531, RM1, RM286, and RM336 fit to be used in analysis of genetic diversity for improved japonica rice variety. The genetic similarity among improved japonica rice varieties from different provinces was closely associated with genetic basis of parents, and was also correlated with latitude and ecological environment where the varieties were bred.

重组Ⅲ型人源化胶原蛋白冻干纤维治疗阴道松弛症随机对照临床试验研究

目的探讨重组Ⅲ型人源化胶原蛋白冻干纤维在治疗阴道松弛症中的临床疗效及安全性。方法2022年6月至2023年3月在重庆医科大学附属第二医院和山西医科大学第一医院确诊的84例阴道松弛症患者纳入研究,随机分为研究组[采用重组Ⅲ型人源化胶原蛋白冻干纤维联合医用Ⅲ型胶原阴道凝胶(加载产品)治疗,42例]和对照组(采用医用Ⅲ型胶原阴道凝胶治疗,42例)。比较两组患者治疗前后阴道松弛分度量化评分改善率、女性性功能指数(FSFI)评分、阴道松弛问卷(VLQ)评分、盆底肌评估总分及不良反应发生率等指标的差异。结果治疗结束后4周研究组阴道松弛量化评分改善率为88.10%(37/42),显著高于对照组(30.95%,13/42),差异有统计学意义(P<0.001)。去除加载产品后研究组的有效率为57.14%。研究组FSFI评分改善及VLQ评分改善显著优效于对照组(P<0.05)。其中在性活动时阴道润滑性、性交痛(改善)、性生活满意度和主观性唤起能力4个方面,研究组改善情况均优于对照组。研究组与对照组在安全性方面无明显差异,均无严重不良事件发生。结论重组Ⅲ型人源化胶原蛋白冻干纤维经阴道注射治疗阴道松弛症具有较好的疗效及安全性。

上皮性卵巢癌化疗耐药及干预的研究进展

目前上皮性卵巢癌的标准治疗包括肿瘤减灭术、辅助化疗及缓解后维持治疗方案,其中药物治疗至关重要,包含铂类/非铂化疗及各类靶向药物,旨在最大限度地消灭肿瘤细胞及延缓疾病进展。随着治疗周期的递增药物敏感性却逐渐下降,化疗耐药严重影响了药物疗效,涉及耐药机制包含药物摄取减少和流出增加、药物解毒增强或激活减少、作用靶点的改变及DNA修复增强、凋亡抑制、肿瘤微环境变化及免疫逃逸等。当前国内外很多研究已关注到需干预耐药来提高疗效,如针对药物的临床研究、免疫治疗和靶向疗法的探索、节拍化疗等方案。了解卵巢癌耐药机制并改善耐药、增强化疗敏感性有利于患者长期受益。