目的研究加速康复外科(enhanced recovery after surgery,ERAS)模式下全膝关节置换术中"鸡尾酒"复合液不同使用方案的有效性及安全性。方法纳入南京医科大学附属苏州医院关节外科2016年6月-2018年6月行全膝关节置换术患者120...目的研究加速康复外科(enhanced recovery after surgery,ERAS)模式下全膝关节置换术中"鸡尾酒"复合液不同使用方案的有效性及安全性。方法纳入南京医科大学附属苏州医院关节外科2016年6月-2018年6月行全膝关节置换术患者120例,采用数字表法随机分为3组:A组将复合液全部进行关节周围浸润注射,B组将复合液完全行关节腔内注射,C组将复合液一半行关节周围浸润注射,另一半行关节腔内注射,每组40例。观察并比较患者年龄、性别、BMI、VAS评分及术后主要观察指标等。结果术后6、8、12、24 h VAS评分,B组最高,C组最低,差异有统计学意义(均P<0.05);术后48 h、72 h VAS评分差异无统计学意义(均P>0.05);术后24 h补救镇痛率B组最高,C组最低,差异有统计学意义(P<0.05);术后最大血红蛋白下降值,C组最低,B组最高,差异具有统计学意义(P<0.05);术后24 h内引流量C组最低,B组最高,差异具有统计学意义(P<0.05);C组患者术后膝关节活动度最大,差异具有统计学意义(P<0.05);术后3 d,C组HSS评分高于其他2组,差异有统计学意义(P<0.05)。3组其他指标比较差异均无统计学意义(均P>0.05)。结论ERAS模式下全膝关节置换术中局部浸润联合关节腔注射"鸡尾酒"复合液,能减轻患者疼痛,减少患者术后失血,并且安全有效,有利于患者术后康复。展开更多
Humidity sensors have been widely applied to detect environment humidity in various fields. However, most of humidity sensors cannot provide performance needed for high sensitivity and fast response. We report one typ...Humidity sensors have been widely applied to detect environment humidity in various fields. However, most of humidity sensors cannot provide performance needed for high sensitivity and fast response. We report one type of capacitive-type humidity sensors composed of laser-scribed graphene(LSG) as sensing electrodes and graphene oxide/tin dioxide(GO/SnO2) as a sensing layer. The LSG is reduced graphene oxide(rGO) electrodes resulted from selective reducing of GO within a GO/SnO2 composite layer by laser scribing method, and the sensing layer is the un-scribed GO/SnO2 composite. The sensor fabrication is a one-step process which is facile and cost-efficient. When a mass ratio of GO:SnO2 in the composite reaches 1:1, the humidity sensor(named as LSG-GS1) has the best properties than other ratios, which exhibits high sensitivity in the range of 11%~97% relative humidity(RH). In addition, the LSG-GS1 also has very quick response/recovery time(20 s for adsorption and 18 s for desorption) when RH changes from 23% to 84%, and very good stability after monitoring for 41 days. Such excellent performances of the humidity sensor can be attributed to synergistic effect of SnO2 and GO within the composite layer.展开更多
Solid polymer electrolytes(SPEs) have been considered as the spotlight in recent years due to their high safety, non-flammability and good flexibility. Nonetheless, high crystallinity of polymer matrix leads to low io...Solid polymer electrolytes(SPEs) have been considered as the spotlight in recent years due to their high safety, non-flammability and good flexibility. Nonetheless, high crystallinity of polymer matrix leads to low ionic conductivity at ambient conditions and retards the practical applications of SPEs. Herein, we report hybrid solid electrolytes(HSE) containing bulky LATP in poly(ethylene oxide)(PEO) matrix, which significantly enhances the electrochemical properties. LATP has been easily obtained by an accessible solid-state method. The solid electrolyte based on 20 wt% LATP in PEO polymer matrix(abbreviated as PEO-20) exhibits an ionic conductivity of 2.1 ×10-5 S·cm-1 at 30 ℃, an order of magnitude higher than 2.9 × 10-6 S·cm-1 of the pristine PEO solid electrolyte(abbreviated as PEO-0), mainly resulting from the decline of crystallinity in polymer matrix. The electrochemical window of PEO-20 can reach 4.84 V at room temperature, compared with 4.40 V for PEO-0, which could be compatible with high-voltage cathode materials.展开更多
文摘目的研究加速康复外科(enhanced recovery after surgery,ERAS)模式下全膝关节置换术中"鸡尾酒"复合液不同使用方案的有效性及安全性。方法纳入南京医科大学附属苏州医院关节外科2016年6月-2018年6月行全膝关节置换术患者120例,采用数字表法随机分为3组:A组将复合液全部进行关节周围浸润注射,B组将复合液完全行关节腔内注射,C组将复合液一半行关节周围浸润注射,另一半行关节腔内注射,每组40例。观察并比较患者年龄、性别、BMI、VAS评分及术后主要观察指标等。结果术后6、8、12、24 h VAS评分,B组最高,C组最低,差异有统计学意义(均P<0.05);术后48 h、72 h VAS评分差异无统计学意义(均P>0.05);术后24 h补救镇痛率B组最高,C组最低,差异有统计学意义(P<0.05);术后最大血红蛋白下降值,C组最低,B组最高,差异具有统计学意义(P<0.05);术后24 h内引流量C组最低,B组最高,差异具有统计学意义(P<0.05);C组患者术后膝关节活动度最大,差异具有统计学意义(P<0.05);术后3 d,C组HSS评分高于其他2组,差异有统计学意义(P<0.05)。3组其他指标比较差异均无统计学意义(均P>0.05)。结论ERAS模式下全膝关节置换术中局部浸润联合关节腔注射"鸡尾酒"复合液,能减轻患者疼痛,减少患者术后失血,并且安全有效,有利于患者术后康复。
基金supported by the Fujian Provincial Department of Science and Technology (No. 2018H0041,2018H0042,2018T3010,2019T3017 and 2019T3024)。
文摘Humidity sensors have been widely applied to detect environment humidity in various fields. However, most of humidity sensors cannot provide performance needed for high sensitivity and fast response. We report one type of capacitive-type humidity sensors composed of laser-scribed graphene(LSG) as sensing electrodes and graphene oxide/tin dioxide(GO/SnO2) as a sensing layer. The LSG is reduced graphene oxide(rGO) electrodes resulted from selective reducing of GO within a GO/SnO2 composite layer by laser scribing method, and the sensing layer is the un-scribed GO/SnO2 composite. The sensor fabrication is a one-step process which is facile and cost-efficient. When a mass ratio of GO:SnO2 in the composite reaches 1:1, the humidity sensor(named as LSG-GS1) has the best properties than other ratios, which exhibits high sensitivity in the range of 11%~97% relative humidity(RH). In addition, the LSG-GS1 also has very quick response/recovery time(20 s for adsorption and 18 s for desorption) when RH changes from 23% to 84%, and very good stability after monitoring for 41 days. Such excellent performances of the humidity sensor can be attributed to synergistic effect of SnO2 and GO within the composite layer.
基金the Fujian Provincial Science and Technology Program (No. 2018H0042,2019T3017)Putian Municipal Science and Technology Program (2019HJSTS009)the DNL Cooperation Fund,CAS (DNL180308)。
文摘Solid polymer electrolytes(SPEs) have been considered as the spotlight in recent years due to their high safety, non-flammability and good flexibility. Nonetheless, high crystallinity of polymer matrix leads to low ionic conductivity at ambient conditions and retards the practical applications of SPEs. Herein, we report hybrid solid electrolytes(HSE) containing bulky LATP in poly(ethylene oxide)(PEO) matrix, which significantly enhances the electrochemical properties. LATP has been easily obtained by an accessible solid-state method. The solid electrolyte based on 20 wt% LATP in PEO polymer matrix(abbreviated as PEO-20) exhibits an ionic conductivity of 2.1 ×10-5 S·cm-1 at 30 ℃, an order of magnitude higher than 2.9 × 10-6 S·cm-1 of the pristine PEO solid electrolyte(abbreviated as PEO-0), mainly resulting from the decline of crystallinity in polymer matrix. The electrochemical window of PEO-20 can reach 4.84 V at room temperature, compared with 4.40 V for PEO-0, which could be compatible with high-voltage cathode materials.
