Objective:To systematically evaluate the efficacy and safety of Tenghuang Jiangu Tablet(藤黄健骨片)in the treatment of discogenic low back pain.Methods:CNKI,WanFang,CBM,VIP,PubMed,EMbase,Cochrane Library and Web of Sc...Objective:To systematically evaluate the efficacy and safety of Tenghuang Jiangu Tablet(藤黄健骨片)in the treatment of discogenic low back pain.Methods:CNKI,WanFang,CBM,VIP,PubMed,EMbase,Cochrane Library and Web of Science were systematically searched to collect the randomized controlled trials(RCTs)of Tenghuang Jiangu Tablet in the treatment of discogenic low back pain.Literature screening and data extraction according to the set criteria were conducted.Cochrane Risk Bias assessment tool was used to evaluate the quality of included RCTs,and Meta-analysis was performed using RevMan 5.4.1 software.Results:A total of 4 studies were included,with a total sample size of 404 cases.The results of Meta-analysis suggested that Tenghuang Jiangu Tablet combined with conventional treatment in the treatment of discogenic low back pain was superior to conventional treatment alone in terms of total clinical response rate(RR=1.21,95%CI[1.09,1.35],P=0.0004),excellent rate of curative effect(RR=1.24,95%CI[1.10,1.41],P=0.0007),lower VAS score(MD=-0.62,95%CI[-0.79,-0.44],P<0.00001)and JOA score(MD=1.84,95%CI[1.35,2.33],P<0.00001).There was no statistical significance in the incidence of adverse reactions between Tenghuang Jiangu Tablet combined with conventional treatment and conventional treatment alone(RR=0.76,95%CI[0.04,15.42],P=0.86).Conclusion:Based on existing research and methods,Tenghuang Jiangu Tablet combined with conventional therapy is effective on discogenic low back pain.Conventional therapy combined with Tenghuang Jiangu Tablet for the treatment of discogenic low back pain may be better than conventional therapy alone.All the adverse reactions occurred during the treatment were mild.There is no evidence that Tenghuang Jiangu Tablet can cause serious adverse reactions.However,the number of existing clinical studies is small and the quality is generally not high.It is suggested to carry out more large-sample and high-quality RCTs,and pay more attention to the long-term efficacy of drugs and the occurrence of adverse reactions,so as to further verify the above conclusions.展开更多
深度卷积神经网络模型在很多公开的可见光目标检测数据集上表现优异,但是在红外目标检测领域,目标样本稀缺一直是制约检测识别精度的难题.针对该问题,本文提出了一种小样本红外图像的样本扩增与目标检测算法.采用基于注意力机制的生成...深度卷积神经网络模型在很多公开的可见光目标检测数据集上表现优异,但是在红外目标检测领域,目标样本稀缺一直是制约检测识别精度的难题.针对该问题,本文提出了一种小样本红外图像的样本扩增与目标检测算法.采用基于注意力机制的生成对抗网络进行红外样本扩增,生成一系列保留原始可见光图像关键区域的红外连续图像,并且使用空间注意力机制等方法进一步提升YOLOv3目标检测算法的识别精度.在Grayscale-Thermal与OSU Color-Thermal红外–可见光数据集上的实验结果表明,本文算法使用的红外样本扩增技术有效提升了深度网络模型对红外目标检测的精度,与原始YOLOv3算法相比,本文算法最高可提升近20%的平均精确率(mean average precision,mAP).展开更多
基金2021 Qihuang Scholars Support Project of State Administration of Traditional Chinese Medicine(National Letter of TCM Education[2022]No.6)National Key Research and Development Program"Modernization of Traditional Chinese Medicine"Project(2018YFC1707400)。
文摘Objective:To systematically evaluate the efficacy and safety of Tenghuang Jiangu Tablet(藤黄健骨片)in the treatment of discogenic low back pain.Methods:CNKI,WanFang,CBM,VIP,PubMed,EMbase,Cochrane Library and Web of Science were systematically searched to collect the randomized controlled trials(RCTs)of Tenghuang Jiangu Tablet in the treatment of discogenic low back pain.Literature screening and data extraction according to the set criteria were conducted.Cochrane Risk Bias assessment tool was used to evaluate the quality of included RCTs,and Meta-analysis was performed using RevMan 5.4.1 software.Results:A total of 4 studies were included,with a total sample size of 404 cases.The results of Meta-analysis suggested that Tenghuang Jiangu Tablet combined with conventional treatment in the treatment of discogenic low back pain was superior to conventional treatment alone in terms of total clinical response rate(RR=1.21,95%CI[1.09,1.35],P=0.0004),excellent rate of curative effect(RR=1.24,95%CI[1.10,1.41],P=0.0007),lower VAS score(MD=-0.62,95%CI[-0.79,-0.44],P<0.00001)and JOA score(MD=1.84,95%CI[1.35,2.33],P<0.00001).There was no statistical significance in the incidence of adverse reactions between Tenghuang Jiangu Tablet combined with conventional treatment and conventional treatment alone(RR=0.76,95%CI[0.04,15.42],P=0.86).Conclusion:Based on existing research and methods,Tenghuang Jiangu Tablet combined with conventional therapy is effective on discogenic low back pain.Conventional therapy combined with Tenghuang Jiangu Tablet for the treatment of discogenic low back pain may be better than conventional therapy alone.All the adverse reactions occurred during the treatment were mild.There is no evidence that Tenghuang Jiangu Tablet can cause serious adverse reactions.However,the number of existing clinical studies is small and the quality is generally not high.It is suggested to carry out more large-sample and high-quality RCTs,and pay more attention to the long-term efficacy of drugs and the occurrence of adverse reactions,so as to further verify the above conclusions.
文摘深度卷积神经网络模型在很多公开的可见光目标检测数据集上表现优异,但是在红外目标检测领域,目标样本稀缺一直是制约检测识别精度的难题.针对该问题,本文提出了一种小样本红外图像的样本扩增与目标检测算法.采用基于注意力机制的生成对抗网络进行红外样本扩增,生成一系列保留原始可见光图像关键区域的红外连续图像,并且使用空间注意力机制等方法进一步提升YOLOv3目标检测算法的识别精度.在Grayscale-Thermal与OSU Color-Thermal红外–可见光数据集上的实验结果表明,本文算法使用的红外样本扩增技术有效提升了深度网络模型对红外目标检测的精度,与原始YOLOv3算法相比,本文算法最高可提升近20%的平均精确率(mean average precision,mAP).
