In Northern China, sandstone-type uranium （U） deposits are mostly developed in Mesozoic-Cenozoic basins. These U deposits are usually hosted in unvarying horizons within the basins and exhibit typical U-forming sedi...In Northern China, sandstone-type uranium （U） deposits are mostly developed in Mesozoic-Cenozoic basins. These U deposits are usually hosted in unvarying horizons within the basins and exhibit typical U-forming sedimentary associations, which is referred to as U-bearing rock series. This study describes the structural features of U-bearing rock series within the main Mesozoic-Cenozoic U-producing continental basins in Kazakhstan, Uzbekistan, and Russia in the western segment of the Central Asian Metallogenic Belt （CAMB）, and Northern China in the eastern segment of the CAMB. We analyze the basic structural conditions and sedimentary environments of U-bearing rock series in Northern China and classify their structural styles in typical basins into river valley, basin margin, and intrabasin uplift margin types. The intrabasin uplift margin structural style proposed in this study can be used to indicate directions for the exploration of sandstone-type U deposits hosted in the center of a basin. At the same time, the study of structural style provides a new idea for exploring sandstone-type U deposits in Mesozoic-Cenozoic basins and it is of great significance to prospecting of sandstone-type uranium deposits.展开更多
The Zhongtiao Mountains, a typical exposure area of Precambrian rocks, are a concentration area of vari-ous types of copper deposit. The rocks were dated using several dating methods. Based on the age data ob-tained b...The Zhongtiao Mountains, a typical exposure area of Precambrian rocks, are a concentration area of vari-ous types of copper deposit. The rocks were dated using several dating methods. Based on the age data ob-tained by means of three methods, several aspects are dealt with: (1) the dating results obtained by differentmethods and their geological implications have been compared; (2) a chronotectonic framework has been con-structed by means of these reliable ages, which indicates that the ages of the rocks of the Proterozoic mobilebelt fall in a time span of 2400 to 2000 Ma during which global magmatic records are lacking and reflects theages of important events in the mobile belt; (3) according to the ages of inherited zircons, neodymium modelage of the depleted mantle sources (T_(DM)) and geochemical and geological data, a model of Precambrianchronocrustal structure has been constructed, representing a typical for the North China craton.展开更多
目的:探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)、基质金属蛋白酶12(matr i x metal loproteinase 12,M MP12)在胆囊癌组织中的表达及其临床意义。方法:以免疫组织化学En Vision二步法检测胆囊癌及癌旁正常胆...目的:探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)、基质金属蛋白酶12(matr i x metal loproteinase 12,M MP12)在胆囊癌组织中的表达及其临床意义。方法:以免疫组织化学En Vision二步法检测胆囊癌及癌旁正常胆囊组织(各50例)的LIFR和MMP12的表达情况。结果:LIFR,MMP12在胆囊癌中表达的阳性率分别为38.0%,36.0%,在癌旁正常胆囊组织中表达的阳性率为82.0%,86.0%;Ⅲ~Ⅳ期胆囊癌LIFR,MMP12的阳性表达率为17.9%,17.9%,Ⅰ~Ⅱ期胆囊癌LIFR,MMP12的阳性表达率为63.6%,59.1%;有淋巴结转移的胆囊癌LIFR,MMP12的阳性表达率为14.8%,11.1%,无淋巴转移的胆囊癌LIFR,MMP12的阳性表达率为65.2%,65.2%。结论:LIFR,MMP12在胆囊癌中的表达水平显著低于癌旁正常胆囊组织;LIFR,MMP12在Ⅲ~Ⅳ期胆囊癌的表达水平低于Ⅰ~Ⅱ期胆囊癌,在有淋巴结转移的胆囊癌中的表达水平低于无淋巴结转移者。LIFR,MMP12表达水平的下降在胆囊癌的发生、发展及转移过程中可能起重要作用。展开更多
基金supported by the undertaken units of subprojects of the Program of Survey on Sandstone-Type Uranium Deposits in Northern Chinathe Ministry of Science and Technology of China(Grant 2015CB453000)the Geological Survey project of China(Grant No.DD20160128)
文摘In Northern China, sandstone-type uranium （U） deposits are mostly developed in Mesozoic-Cenozoic basins. These U deposits are usually hosted in unvarying horizons within the basins and exhibit typical U-forming sedimentary associations, which is referred to as U-bearing rock series. This study describes the structural features of U-bearing rock series within the main Mesozoic-Cenozoic U-producing continental basins in Kazakhstan, Uzbekistan, and Russia in the western segment of the Central Asian Metallogenic Belt （CAMB）, and Northern China in the eastern segment of the CAMB. We analyze the basic structural conditions and sedimentary environments of U-bearing rock series in Northern China and classify their structural styles in typical basins into river valley, basin margin, and intrabasin uplift margin types. The intrabasin uplift margin structural style proposed in this study can be used to indicate directions for the exploration of sandstone-type U deposits hosted in the center of a basin. At the same time, the study of structural style provides a new idea for exploring sandstone-type U deposits in Mesozoic-Cenozoic basins and it is of great significance to prospecting of sandstone-type uranium deposits.
文摘The Zhongtiao Mountains, a typical exposure area of Precambrian rocks, are a concentration area of vari-ous types of copper deposit. The rocks were dated using several dating methods. Based on the age data ob-tained by means of three methods, several aspects are dealt with: (1) the dating results obtained by differentmethods and their geological implications have been compared; (2) a chronotectonic framework has been con-structed by means of these reliable ages, which indicates that the ages of the rocks of the Proterozoic mobilebelt fall in a time span of 2400 to 2000 Ma during which global magmatic records are lacking and reflects theages of important events in the mobile belt; (3) according to the ages of inherited zircons, neodymium modelage of the depleted mantle sources (T_(DM)) and geochemical and geological data, a model of Precambrianchronocrustal structure has been constructed, representing a typical for the North China craton.
文摘目的:探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)、基质金属蛋白酶12(matr i x metal loproteinase 12,M MP12)在胆囊癌组织中的表达及其临床意义。方法:以免疫组织化学En Vision二步法检测胆囊癌及癌旁正常胆囊组织(各50例)的LIFR和MMP12的表达情况。结果:LIFR,MMP12在胆囊癌中表达的阳性率分别为38.0%,36.0%,在癌旁正常胆囊组织中表达的阳性率为82.0%,86.0%;Ⅲ~Ⅳ期胆囊癌LIFR,MMP12的阳性表达率为17.9%,17.9%,Ⅰ~Ⅱ期胆囊癌LIFR,MMP12的阳性表达率为63.6%,59.1%;有淋巴结转移的胆囊癌LIFR,MMP12的阳性表达率为14.8%,11.1%,无淋巴转移的胆囊癌LIFR,MMP12的阳性表达率为65.2%,65.2%。结论:LIFR,MMP12在胆囊癌中的表达水平显著低于癌旁正常胆囊组织;LIFR,MMP12在Ⅲ~Ⅳ期胆囊癌的表达水平低于Ⅰ~Ⅱ期胆囊癌,在有淋巴结转移的胆囊癌中的表达水平低于无淋巴结转移者。LIFR,MMP12表达水平的下降在胆囊癌的发生、发展及转移过程中可能起重要作用。
