新型单传感器半主动悬架控制算法机理研究

半主动悬架控制算法研究,对提高汽车的平顺性和操纵稳定性,具有非常重要的意义。本文首先建立了一种三自由度车辆模型,并基于试验场采集的试验数据作为模型的工况输入。然后,提出了一种新型单传感器算法,并基于建立的控制算法和三自由度车辆模型闭环仿真平台,对新型单传感器算法进行了仿真分析,从理论上验证了算法的优势以及算法参数对平顺性的影响规律。最后,在闭环仿真平台中对新型单传感器算法的参数进行了优化,结果表明,相对于被动减振器,在鹅卵石路面和长波路面上,新型单传感器算法车身质心加速度RMS指数分别降低了21%和14%,大幅提升了车辆的舒适性。

贾小强中药熏洗坐浴法治疗肛周湿疹经验

肛周湿疹是肛肠科常见病,主要临床表现为瘙痒、肛门潮湿等,常反复发作,肛门局部可见丘疹、结痂、脱屑等皮损表现,严重影响患者的生活质量。肛周湿疹多以风湿挟热、脉络瘀阻为主,风湿热互结、气血不畅是其核心病机。贾小强教授认为治疗肛周湿疹应审证求因,明辨病机,治病求本,祛风、活血、胜湿三法合用。祛风胜湿是治疗本病的常法,活血化瘀法是提高疗效、缩短病程、减少复发的关键。

不同麻醉方式致HIV感染期患者术后并发症的临床研究

目的比较全身麻醉(GA)和腰硬联合麻醉(CSEA)对接受手术的人类免疫缺陷病毒(HIV)感染期患者术后并发症的影响。方法回顾性分析重庆市公共卫生医疗救治中心2015年1月至2017年12月经确证为HIV阳性,临床分期为无症状感染期的57例患者的临床资料,其中腰硬联合麻醉组21例,全身麻醉组36例。在术前和术后24 h于清晨空腹状态下抽取腰硬联合麻醉组和全身麻醉组患者外周静脉血5～10 mL,进行CD4+和CD8+T淋巴细胞计数。分别记录患者性别、年龄、体质量、患病时长、手术时长、麻醉时间、术后并发症,应用非条件Logistic回归分析HIV感染期患者术后肺部感染并发症的危险因素。结果全身麻醉组患者麻醉时间为(189.2±107.5) min,明显长于腰硬联合麻醉组的(109.5±68.5) min,肺部感染发生率为33.3%,明显高于腰硬联合麻醉组的9.5%,且两组男性人数均高于女性,差异均有统计学意义(P<0.05);全身麻醉组患者术后与术前24 h外周血CD4+T淋巴细胞计数[(317.7±57.8)%vs (349.7±60.8)%]和CD4+/CD8+比值[(0.50±0.11)%vs (0.58±0.18)%]比较,术后均低于术前,术后CD8+T淋巴细胞计数为(597.4±59.6)%,高于术前的(569.2±60.3)%,差异均有统计学意义(P<0.05),而腰硬联合麻醉组患者手术前后上述各项指标比较差异均无统计学意义(P>0.05);对HIV感染期患者术后肺部感染并发症做非条件Logistic回归分析,发现年龄(OR=1.45,95%CI=1.07～2.97,P=0.004)、不同麻醉方式(OR=2.97,95%CI=1.18～10.45,P=0.009)、患病时间(OR=1.17,95%CI=1.04～1.23,P=0.003)是发生术后肺部感染并发症的危险因素。结论在HIV感染期患者手术中,全身麻醉对术后肺部感染的影响较腰硬联合麻醉显著。

EPS超前滞后校正器模型开发机理研究

近年来,随着机电一体化和汽车控制系统的发展,EPS系统在汽车上得到了广泛的应用。超前滞后校正器因其独特的频率特性,能对不同工况下EPS系统的工作性能进行优化补偿,成为了目前的研究重点。基于此,本文首先对超前滞后校正器进行机理分析,设计了一种新型超前滞后校正器,并对该传递函数的特性进行分析。其次,基于新型超前滞后校正器传递函数,进行离散化机理分析,同时考虑到实际控制器的数据精度,设计了一种参数修正算法,提高校正器在实际离散控制器中的精度。最后,基于simulink设计了超前滞后校正器模型,并进行了仿真验证。结果表明,新型超前滞后校正器参数调节便利,离散处理后的校正器与理论值吻合、精度高。

Effect of High Suspension and Low Incision Surgery Based on Traditional Ligation of Chinese Medicine in Treatment of Mixed Haemorrhoids:A Multi-centre,Randomized,Single-Blind,Non-inferiority Clinical Trial

Objective:To observe the clinical effect of high suspension and low incision(HSLI)surgery on mixed haemorrhoids,compared with Milligan-Morgan haemorrhoidectomy.Methods:A multi-centre,randomized,singleblind,non-inferiority clinical trial was performed.Participants with mixed haemorrhoids from Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing Rectum Hospital,Air Force Medical Center of People's Liberation Army of China,and Puyang Hospital of Traditional Chinese Medicine were enrolled from September 2016 to March 2018.By using a blocked randomization scheme,participants were assigned to two groups.The experimental group was treated with HSLI,while the control group was treated with Milligan-Morgan haemorrhoidectomy.The primary outcome was the clinical effect evaluated at 12 weeks after operation.The secondary outcomes included the number of haemorrhoids treated during the operation,pain scores,use of analgesics,postoperative oedema,wound healing,incidence of anal stenosis,anorectal manometry after operation,as well as surgical duration,length of stay and total hospitalization expenses.A safety evaluation was also conducted.Results:In total,246 eligible participants were enrolled,with 123 cases in each group.There was no significant difference in the clinical effect between the two groups(100.00% vs.99.19%,P>0.05).Compared with the control group,the number of external haemorrhoids treated during the operation and the pain scores after operation were significantly reduced in the experimental group(P<0.05 or P<0.01);the patient number with wound healing at 2 weeks after operation and the functional length of anal canal at 12 weeks after operation were significantly increased in the experimental group(P<0.05).There was no significant difference in the incidence of anal stenosis,the numbers of patients using analgesics and patients with postoperative oedema between the two groups after operation(P>0.05).The surgical duration and length of stay in the experimental group were significantly longer than those in the control group,and the total hospitalization expense was significantly higher than that in the control group(all P<0.05).No adverse events were reported in either group during the whole trial or follow-up period.Conclusion:HSLI had the advantages of preserving the skin of anal canal completely,alleviating postsurgical pain and promoting rapid recovery after operation.(Registration No.Chi CTR1900022883).