目的:调查了解国内医院开展治疗药物监测(therapeutic drug monitoring,TDM)和个体化给药基因检测(gene test for personalized medication,GTPM)项目的开展情况。方法:利用互联网技术,通过移动网络平台设计、发送、提交、回收问卷并统...目的:调查了解国内医院开展治疗药物监测(therapeutic drug monitoring,TDM)和个体化给药基因检测(gene test for personalized medication,GTPM)项目的开展情况。方法:利用互联网技术,通过移动网络平台设计、发送、提交、回收问卷并统计分析。结果:回收的有效问卷覆盖了除海南省以外的所有中国大陆省份,参与调查的医院中公立三级医院占比近9成。约71%的医院开展了TDM,检测量较大的品种有丙戊酸钠、环孢素、他克莫司;约48%的医院开展了GTPM,检测量较大的品种是氯吡格雷、华法林及叶酸相关基因。只有70%左右的调查医院参加了TDM和GTPM室间质评。结论:本次问卷调查结果较好地反映了当前我国医院个体化给药检测项目的开展现状,发现了质控意识不足、GTPM有规不依、项目收费标准不统一等问题,建议相关卫生部门进一步加强管理。展开更多
The characteristic spectrum and its main wavelength of Ru porcelain glaze are measured by color difference instrument to determine the relations between glaze color and its main wavelength. The content of the 30 color...The characteristic spectrum and its main wavelength of Ru porcelain glaze are measured by color difference instrument to determine the relations between glaze color and its main wavelength. The content of the 30 coloring elements in Ru porcelain is determined by neutron activation analysis (NAA), which showed that iron is the major coloring element. Mossbauer spectroscopy analysis shows that the iron element in the glaze exists in the form of structural iron (Fe2+, Fe3+). The quantitative relationship between the main wavelength of glaze in various colors and the relative content of structural iron (Fe2+/Fe3+) is determined. Thus the coloring mechanism of Ru porcelain is investigated entirely.展开更多
文摘目的:调查了解国内医院开展治疗药物监测(therapeutic drug monitoring,TDM)和个体化给药基因检测(gene test for personalized medication,GTPM)项目的开展情况。方法:利用互联网技术,通过移动网络平台设计、发送、提交、回收问卷并统计分析。结果:回收的有效问卷覆盖了除海南省以外的所有中国大陆省份,参与调查的医院中公立三级医院占比近9成。约71%的医院开展了TDM,检测量较大的品种有丙戊酸钠、环孢素、他克莫司;约48%的医院开展了GTPM,检测量较大的品种是氯吡格雷、华法林及叶酸相关基因。只有70%左右的调查医院参加了TDM和GTPM室间质评。结论:本次问卷调查结果较好地反映了当前我国医院个体化给药检测项目的开展现状,发现了质控意识不足、GTPM有规不依、项目收费标准不统一等问题,建议相关卫生部门进一步加强管理。
基金This work was supported by the National Natural Science Foundation of China (Grant Nos. 59872032 and 10175053)the Open Laboratory of Nuclear Analysis Techniques of the Chinese Academy of Sciences (Grant No. 99B006)the Science and Technology Committee
文摘The characteristic spectrum and its main wavelength of Ru porcelain glaze are measured by color difference instrument to determine the relations between glaze color and its main wavelength. The content of the 30 coloring elements in Ru porcelain is determined by neutron activation analysis (NAA), which showed that iron is the major coloring element. Mossbauer spectroscopy analysis shows that the iron element in the glaze exists in the form of structural iron (Fe2+, Fe3+). The quantitative relationship between the main wavelength of glaze in various colors and the relative content of structural iron (Fe2+/Fe3+) is determined. Thus the coloring mechanism of Ru porcelain is investigated entirely.
