目的分析妊娠期糖尿病(GDM)伴亚临床甲状腺功能减退症(甲减)孕妇采取左旋甲状腺素治疗的效果。方法66例GDM伴亚临床甲减孕妇,采用随机数字表法分为观察组和对照组,每组33例。对照组患者采取胰岛素治疗,观察组患者采取胰岛素联合左旋甲...目的分析妊娠期糖尿病(GDM)伴亚临床甲状腺功能减退症(甲减)孕妇采取左旋甲状腺素治疗的效果。方法66例GDM伴亚临床甲减孕妇,采用随机数字表法分为观察组和对照组,每组33例。对照组患者采取胰岛素治疗,观察组患者采取胰岛素联合左旋甲状腺素治疗。对比两组治疗前后甲状腺功能指标[促甲状腺激素(FSH)、血清游离甲状腺素(FT_(4))、游离三碘甲状腺原氨酸(FT_(3))]、血糖指标[餐后2 h血糖(2 h PBG)、空腹血糖(FPG)]以及并发症发生率、新生儿结局。结果治疗后,两组FT_(4)水平对比差异无统计学意义(P>0.05);观察组FT_(3)水平(6.77±0.78)pmol/L高于对照组的(5.01±0.49)pmol/L,FSH水平(3.26±1.07)mU/L低于对照组的(8.38±1.74)mU/L,差异具有统计学意义(P<0.05)。治疗后,观察组2 h PBG、FPG水平分别为(5.72±0.26)、(5.32±0.39)mmol/L,均低于对照组的(6.29±0.40)、(5.93±0.24)mmol/L,差异具有统计学意义(P<0.05)。观察组产后出血、胎膜早破、羊水异常、早产、前置胎盘、妊娠期蛋白尿、妊娠期高血压、贫血发生率分别为3.03%、6.06%、6.06%、3.03%、15.15%、3.03%、3.03%、3.03%,均低于对照组的18.18%、30.30%、24.24%、18.18%、45.45%、18.18%、18.18%、18.18%,差异具有统计学意义(P<0.05)。观察组死胎、胎儿畸形、低体重儿胎儿宫内窘迫发生率分别为0、3.03%、3.03%、3.03%,均低于对照组的15.15%、18.18%、21.21%、24.24%,差异具有统计学意义(P<0.05)。结论左旋甲状腺素在GDM伴亚临床甲减孕妇治疗中效果良好,可有效改善孕妇甲状腺功能指标及血糖水平,降低并发症发生率,改善新生儿结局。展开更多
The horizontal vorticity equation used in this study was obtained using the equations of motion in the pressure coordinate system without considering friction, to reveal its relationship with vertical shear. By diagno...The horizontal vorticity equation used in this study was obtained using the equations of motion in the pressure coordinate system without considering friction, to reveal its relationship with vertical shear. By diagnostically analyzing each term in the horizontal vorticity equation during a squall line process that occurred on 19 June 2010, we found that the non-thermal wind term had a negative contribution to the local change of upward movement in the low-level atmosphere, and that its impact changed gradually from negative to positive with altitude, which could influence upward movement in the mid-and upper-level atmosphere greatly. The contribution of upward vertical transport to vertical movement was the largest in the low-level atmosphere, but had negative contribution to the upper-level atmosphere. These features were most evident in the development stage of the squall line. Based on analysis of convection cells along a squall line, we found that in the process of cell development diabatic heating caused the subsidence of constant potential temperature surface and non-geostrophic motion, which then triggered strong convergence of horizontal acceleration in the mid-level atmosphere and divergence of horizontal acceleration in the upper-level atmosphere. These changes of horizontal wind field could cause a counterclockwise increment of the horizontal vorticity around the warm cell, which then generated an increase of upward movement. This was the main reason why the non-thermal wind term had the largest contribution to the strengthening of upward movement in the mid-and upper-level atmosphere. The vertical transport of large value of horizontal vorticity was the key to trigger convection in this squall line process.展开更多
A mesh editing framework is presented in this paper, which integrates Free-Form Deformation (FFD) and geometry signal processing. By using simplified model from original mesh, the editing task can be accomplished with...A mesh editing framework is presented in this paper, which integrates Free-Form Deformation (FFD) and geometry signal processing. By using simplified model from original mesh, the editing task can be accomplished with a few operations. We take the deformation of the proxy and the position coordinates of the mesh models as geometry signal. Wavelet analysis is em- ployed to separate local detail information gracefully. The crucial innovation of this paper is a new adaptive regular sampling approach for our signal analysis based editing framework. In our approach, an original mesh is resampled and then refined itera- tively which reflects optimization of our proposed spectrum preserving energy. As an extension of our spectrum editing scheme, the editing principle is applied to geometry details transferring, which brings satisfying results.展开更多
文摘目的分析妊娠期糖尿病(GDM)伴亚临床甲状腺功能减退症(甲减)孕妇采取左旋甲状腺素治疗的效果。方法66例GDM伴亚临床甲减孕妇,采用随机数字表法分为观察组和对照组,每组33例。对照组患者采取胰岛素治疗,观察组患者采取胰岛素联合左旋甲状腺素治疗。对比两组治疗前后甲状腺功能指标[促甲状腺激素(FSH)、血清游离甲状腺素(FT_(4))、游离三碘甲状腺原氨酸(FT_(3))]、血糖指标[餐后2 h血糖(2 h PBG)、空腹血糖(FPG)]以及并发症发生率、新生儿结局。结果治疗后,两组FT_(4)水平对比差异无统计学意义(P>0.05);观察组FT_(3)水平(6.77±0.78)pmol/L高于对照组的(5.01±0.49)pmol/L,FSH水平(3.26±1.07)mU/L低于对照组的(8.38±1.74)mU/L,差异具有统计学意义(P<0.05)。治疗后,观察组2 h PBG、FPG水平分别为(5.72±0.26)、(5.32±0.39)mmol/L,均低于对照组的(6.29±0.40)、(5.93±0.24)mmol/L,差异具有统计学意义(P<0.05)。观察组产后出血、胎膜早破、羊水异常、早产、前置胎盘、妊娠期蛋白尿、妊娠期高血压、贫血发生率分别为3.03%、6.06%、6.06%、3.03%、15.15%、3.03%、3.03%、3.03%,均低于对照组的18.18%、30.30%、24.24%、18.18%、45.45%、18.18%、18.18%、18.18%,差异具有统计学意义(P<0.05)。观察组死胎、胎儿畸形、低体重儿胎儿宫内窘迫发生率分别为0、3.03%、3.03%、3.03%,均低于对照组的15.15%、18.18%、21.21%、24.24%,差异具有统计学意义(P<0.05)。结论左旋甲状腺素在GDM伴亚临床甲减孕妇治疗中效果良好,可有效改善孕妇甲状腺功能指标及血糖水平,降低并发症发生率,改善新生儿结局。
基金National Key Basic Research Development Program“973”(2013CB430103)State Key Laboratory of Severe Weather,Chinese Academy of Meteorological Sciences(2015LASW-A07)National Natural Science Funding(41375058,41530427)
文摘The horizontal vorticity equation used in this study was obtained using the equations of motion in the pressure coordinate system without considering friction, to reveal its relationship with vertical shear. By diagnostically analyzing each term in the horizontal vorticity equation during a squall line process that occurred on 19 June 2010, we found that the non-thermal wind term had a negative contribution to the local change of upward movement in the low-level atmosphere, and that its impact changed gradually from negative to positive with altitude, which could influence upward movement in the mid-and upper-level atmosphere greatly. The contribution of upward vertical transport to vertical movement was the largest in the low-level atmosphere, but had negative contribution to the upper-level atmosphere. These features were most evident in the development stage of the squall line. Based on analysis of convection cells along a squall line, we found that in the process of cell development diabatic heating caused the subsidence of constant potential temperature surface and non-geostrophic motion, which then triggered strong convergence of horizontal acceleration in the mid-level atmosphere and divergence of horizontal acceleration in the upper-level atmosphere. These changes of horizontal wind field could cause a counterclockwise increment of the horizontal vorticity around the warm cell, which then generated an increase of upward movement. This was the main reason why the non-thermal wind term had the largest contribution to the strengthening of upward movement in the mid-and upper-level atmosphere. The vertical transport of large value of horizontal vorticity was the key to trigger convection in this squall line process.
基金Project supported by the National Basic Research Program (973) of China (No. 2002CB312102), and the National Natural Science Foun-dation of China (Nos. 60021201, 60333010 and 60505001)
文摘A mesh editing framework is presented in this paper, which integrates Free-Form Deformation (FFD) and geometry signal processing. By using simplified model from original mesh, the editing task can be accomplished with a few operations. We take the deformation of the proxy and the position coordinates of the mesh models as geometry signal. Wavelet analysis is em- ployed to separate local detail information gracefully. The crucial innovation of this paper is a new adaptive regular sampling approach for our signal analysis based editing framework. In our approach, an original mesh is resampled and then refined itera- tively which reflects optimization of our proposed spectrum preserving energy. As an extension of our spectrum editing scheme, the editing principle is applied to geometry details transferring, which brings satisfying results.
