Helicobacter pylori （H. pylori） infection is a common etiological factor leading to chronic gastritis and peptic ulcer. In addition, there is a close relationship between H. pylori infection and non-ulcer dyspepsia ...Helicobacter pylori （H. pylori） infection is a common etiological factor leading to chronic gastritis and peptic ulcer. In addition, there is a close relationship between H. pylori infection and non-ulcer dyspepsia or gastric cancer. The high incidence of H. pylori infection in pediatric patients in developing countries is thought to inhibit their physical development because of malnutrition, anaemia and growth retardation. Anti-H. pylori therapy is recommended in children with H. pylori-induced gastritis and ulcer. The intake of high-dose broad-spectrum antibiotics may cause serious side effects including the alteration of intestinal flora, fungal infection, impaired liver function, and drug resistance. In recent years, simultaneous administration of probiotics has been used to alleviate the side effects of drug therapy and boost the therapeutic effectiveness of H. pylori eradication. In this study, we investigated changes in the intestinal microbial flora in H. pylori infected children and after H. pylori eradication therapy. We attempted to establish a basis for future research into the role of probiotics in anti- H. pylori treatment.展开更多
Background It has been 11 years since newborn screening started in Zhejiang in 1999.The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.Methods Blood sample...Background It has been 11 years since newborn screening started in Zhejiang in 1999.The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.Methods Blood samples were collected from the heels of newborns 72 hours after birth.We have conducted laboratory tests that the congenital hypothyroidism （CH） and circulating levels of thyroid-stimulating hormone （TSH） was detected.Blood phenylalanine （Phe） was detected for phenylketonuria （PKU）.Dissociation-enhanced lanthanide fluorescent immunoassay （DELFIA） was used for detection.Results From 1999 to 2009,3875228 newborns were screened and 2309 cases were confirmed as CH and 155 cases were confirmed as PKU.The incidence of CH and PKU were 1：1678 and 1：25 001 respectively.Conclusion In 11 years,the Zhejiang newborn screening center screened more than 3.8 million newboms,and helped more than 2000 CH and PKU patients to obtain early treatment in order to prevent physical disability and mental retardation.展开更多
Much has been achieved in child health care over the .past 60 years since the founding of People＇s Republic of China in 1949. In the early years after 1949, a series of new laws provided the basis for the evolution o...Much has been achieved in child health care over the .past 60 years since the founding of People＇s Republic of China in 1949. In the early years after 1949, a series of new laws provided the basis for the evolution of preventive medicine, vaccination, antibiotic drug treatment and the set-up of maternal and child health care institutions in China. Since the 1980s, programs aiming at controlling child mortality and protecting child health have been put into effect, greatly promoting child health care and primary prevention.展开更多
文摘Helicobacter pylori （H. pylori） infection is a common etiological factor leading to chronic gastritis and peptic ulcer. In addition, there is a close relationship between H. pylori infection and non-ulcer dyspepsia or gastric cancer. The high incidence of H. pylori infection in pediatric patients in developing countries is thought to inhibit their physical development because of malnutrition, anaemia and growth retardation. Anti-H. pylori therapy is recommended in children with H. pylori-induced gastritis and ulcer. The intake of high-dose broad-spectrum antibiotics may cause serious side effects including the alteration of intestinal flora, fungal infection, impaired liver function, and drug resistance. In recent years, simultaneous administration of probiotics has been used to alleviate the side effects of drug therapy and boost the therapeutic effectiveness of H. pylori eradication. In this study, we investigated changes in the intestinal microbial flora in H. pylori infected children and after H. pylori eradication therapy. We attempted to establish a basis for future research into the role of probiotics in anti- H. pylori treatment.
文摘Background It has been 11 years since newborn screening started in Zhejiang in 1999.The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.Methods Blood samples were collected from the heels of newborns 72 hours after birth.We have conducted laboratory tests that the congenital hypothyroidism （CH） and circulating levels of thyroid-stimulating hormone （TSH） was detected.Blood phenylalanine （Phe） was detected for phenylketonuria （PKU）.Dissociation-enhanced lanthanide fluorescent immunoassay （DELFIA） was used for detection.Results From 1999 to 2009,3875228 newborns were screened and 2309 cases were confirmed as CH and 155 cases were confirmed as PKU.The incidence of CH and PKU were 1：1678 and 1：25 001 respectively.Conclusion In 11 years,the Zhejiang newborn screening center screened more than 3.8 million newboms,and helped more than 2000 CH and PKU patients to obtain early treatment in order to prevent physical disability and mental retardation.
文摘Much has been achieved in child health care over the .past 60 years since the founding of People＇s Republic of China in 1949. In the early years after 1949, a series of new laws provided the basis for the evolution of preventive medicine, vaccination, antibiotic drug treatment and the set-up of maternal and child health care institutions in China. Since the 1980s, programs aiming at controlling child mortality and protecting child health have been put into effect, greatly promoting child health care and primary prevention.
