Objective To study the relationship between syndrome elements and anterior communicating artery(ACoA)opening in patients with symptomatic severe carotid artery stenosis/occlusion.Methods Thirty-six patients with sympt...Objective To study the relationship between syndrome elements and anterior communicating artery(ACoA)opening in patients with symptomatic severe carotid artery stenosis/occlusion.Methods Thirty-six patients with symptomatic severe carotid stenosis/occlusion were collected,including 26 patients with cerebral infarction and 10 patients with transient ischemic attack(TIA).Syndrome elements at five time points were collected.Computer tomography angiography(CTA)combined with magenic resonance angiograp(MRA)was used to evaluate the primary collateral circulation,and the prognosis and syndrome elements were statistically analyzed according to whether the ACoA was open or not.Results The ACoA was open more in the primary collateral circulation among patients with symptomatic severe carotid stenosis/occlusion.There was a statistically significant difference in national institute of health stroke scale(NIHSS)score improvement and good prognosis[the modified rankin scale(mRS)≤2]between the ACoA open group and the ACoA nonopen group on the 90th day(P<0.05).The proportion of patients with internal wind syndrome,blood stasis syndrome,Qi deficiency syndrome,and Yin deficiency syndrome in the ACoA non-open group was higher than that in the open group.Conclusion In the patients with severe carotid artery stenosis/occlusion,the group with presence of anterior communicating artery had better prognosis.The syndrome elements are more complex in the group without the presence of anterior communicating artery.The proportion of Qi deficiency syndrome was positively correlated with the non-opening of anterior communicating artery.The imaging evaluation of collateral circulation can provide guidance for syndrome differentiation and treatment.展开更多
In the current extensive studies of layered two-dimensional （2D） materials, compared to hexagonal structures such as graphene, hBN, and MoS2, low- symmetry 2D materials have shown great potential for applications in...In the current extensive studies of layered two-dimensional （2D） materials, compared to hexagonal structures such as graphene, hBN, and MoS2, low- symmetry 2D materials have shown great potential for applications in anisotropic devices. Rhenium diselenide （ReSe2） possesses the bulk space group P1 and belongs to the triclinic crystal system with a deformed cadmium-iodide-type structure. Here, we propose an electron diffraction-based method to distinguish the monolayer ReSe2 membrane from multilayer ReSe2 and its two different vertical orientations. Our method is also applicable to other low-symmetry crystal systems, including both triclinic and monoclinic lattices, as long as their third unit-cell basis vectors are not perpendicular to the basal plane. Our experimental results are well explained by kinematical electron diffraction theory and the corresponding simulations. Generalization of our method to other 2D materials, such as ~：raphene, is also discussed.展开更多
基金We thank for the funding support from the Science&Technology Development Fund of Tianjin Education Commission for Higher Education(No.2017KJ150).
文摘Objective To study the relationship between syndrome elements and anterior communicating artery(ACoA)opening in patients with symptomatic severe carotid artery stenosis/occlusion.Methods Thirty-six patients with symptomatic severe carotid stenosis/occlusion were collected,including 26 patients with cerebral infarction and 10 patients with transient ischemic attack(TIA).Syndrome elements at five time points were collected.Computer tomography angiography(CTA)combined with magenic resonance angiograp(MRA)was used to evaluate the primary collateral circulation,and the prognosis and syndrome elements were statistically analyzed according to whether the ACoA was open or not.Results The ACoA was open more in the primary collateral circulation among patients with symptomatic severe carotid stenosis/occlusion.There was a statistically significant difference in national institute of health stroke scale(NIHSS)score improvement and good prognosis[the modified rankin scale(mRS)≤2]between the ACoA open group and the ACoA nonopen group on the 90th day(P<0.05).The proportion of patients with internal wind syndrome,blood stasis syndrome,Qi deficiency syndrome,and Yin deficiency syndrome in the ACoA non-open group was higher than that in the open group.Conclusion In the patients with severe carotid artery stenosis/occlusion,the group with presence of anterior communicating artery had better prognosis.The syndrome elements are more complex in the group without the presence of anterior communicating artery.The proportion of Qi deficiency syndrome was positively correlated with the non-opening of anterior communicating artery.The imaging evaluation of collateral circulation can provide guidance for syndrome differentiation and treatment.
基金This work is financially supported by the National Basic Research Program of China （Nos. 2014CB932500 and 2015CB921004）, the National Natural Science Foundation of China （Nos. 51472215, 51222202, 61571197 and 61172011）, the 111 project （No. B16042） and MOST 104-2112-M-011-002-MY3. The authors would like to thank Prof. Christoph Koch fromHumbold University of Berlin for the fruitful dis- cussions on multislice simulations. J. Y. acknowledges the EPSRC （UK） funding （Nos. EP/G070326 and EP/ J022098） and supports from Pao Yu-Kong International Foundation for a Chair Professorship in ZJU. This work made use of the resources of the Center of Electron Microscopy of Zhejiang University
文摘In the current extensive studies of layered two-dimensional （2D） materials, compared to hexagonal structures such as graphene, hBN, and MoS2, low- symmetry 2D materials have shown great potential for applications in anisotropic devices. Rhenium diselenide （ReSe2） possesses the bulk space group P1 and belongs to the triclinic crystal system with a deformed cadmium-iodide-type structure. Here, we propose an electron diffraction-based method to distinguish the monolayer ReSe2 membrane from multilayer ReSe2 and its two different vertical orientations. Our method is also applicable to other low-symmetry crystal systems, including both triclinic and monoclinic lattices, as long as their third unit-cell basis vectors are not perpendicular to the basal plane. Our experimental results are well explained by kinematical electron diffraction theory and the corresponding simulations. Generalization of our method to other 2D materials, such as ~：raphene, is also discussed.
