Iron is an important element that maintains the normal operation of the body.It not only participates in various physiological reactions as a component of various enzymes,but also is an indispensable component in the ...Iron is an important element that maintains the normal operation of the body.It not only participates in various physiological reactions as a component of various enzymes,but also is an indispensable component in the synthesis of hemoglobin(Hb)and myoglobin,which transport oxygen.About two-thirds of the iron in the body is stored in the Hb of red blood cells,with a small amount present in myoglobin in muscle tissue and enzymes required for various metabolic reactions.The remaining amount is mostly in the form of ferritin as a mobilized iron reserve.When dietary iron intake is limited and the stored iron in the body is insufficient or depleted,iron deficiency occurs.Iron deficiency can be further divided into three stages based on their severity,namely iron deficiency(ID),iron deficiency erythropoiesis(IDE),and iron deficiency anemia(IDA).This study aims to explore the prevalence,diagnosis and differentiation,influencing factors,and preventive interventions of iron deficiency.展开更多
目的探讨儿童皮肌炎的磁共振表现及其与临床,特别是肌酶异常的关系。方法分析临床确诊的50例皮肌炎患儿大腿磁共振图像,了解皮肤、皮下结缔组织、肌筋膜、肌肉受损比例;同时根据磁共振图像中肌肉水肿范围,将患儿分为由轻到重的1、2、3级...目的探讨儿童皮肌炎的磁共振表现及其与临床,特别是肌酶异常的关系。方法分析临床确诊的50例皮肌炎患儿大腿磁共振图像,了解皮肤、皮下结缔组织、肌筋膜、肌肉受损比例;同时根据磁共振图像中肌肉水肿范围,将患儿分为由轻到重的1、2、3级组,比较各组肌酶水平,了解肌肉损害程度与肌酶升高的相关性。大腿MRI检查序列包括:冠状面及横断面,分别采用快速自旋回波序列FSE T 1 W、抑脂序列STIR。结果 50例皮肌炎患儿中,男26例、女24例,中位年龄4.5(3.0~7.5)岁;肌肉水肿49例,肌筋膜炎28例,皮下结缔组织炎9例,皮肤增厚4例。肌肉水肿1级16例、2级24例、3级9例;肌肉水肿2级组肌酶水平均较另两组高,但仅AST与另两组的差异有统计学意义(P<0.05)。结论磁共振成像易检出皮肌炎肌肉水肿等肌肉损害,有助于判断疾病严重程度及累及范围;皮肌炎患儿肌肉水肿程度与肌酶水平不平行。展开更多
文摘Iron is an important element that maintains the normal operation of the body.It not only participates in various physiological reactions as a component of various enzymes,but also is an indispensable component in the synthesis of hemoglobin(Hb)and myoglobin,which transport oxygen.About two-thirds of the iron in the body is stored in the Hb of red blood cells,with a small amount present in myoglobin in muscle tissue and enzymes required for various metabolic reactions.The remaining amount is mostly in the form of ferritin as a mobilized iron reserve.When dietary iron intake is limited and the stored iron in the body is insufficient or depleted,iron deficiency occurs.Iron deficiency can be further divided into three stages based on their severity,namely iron deficiency(ID),iron deficiency erythropoiesis(IDE),and iron deficiency anemia(IDA).This study aims to explore the prevalence,diagnosis and differentiation,influencing factors,and preventive interventions of iron deficiency.
文摘目的探讨儿童皮肌炎的磁共振表现及其与临床,特别是肌酶异常的关系。方法分析临床确诊的50例皮肌炎患儿大腿磁共振图像,了解皮肤、皮下结缔组织、肌筋膜、肌肉受损比例;同时根据磁共振图像中肌肉水肿范围,将患儿分为由轻到重的1、2、3级组,比较各组肌酶水平,了解肌肉损害程度与肌酶升高的相关性。大腿MRI检查序列包括:冠状面及横断面,分别采用快速自旋回波序列FSE T 1 W、抑脂序列STIR。结果 50例皮肌炎患儿中,男26例、女24例,中位年龄4.5(3.0~7.5)岁;肌肉水肿49例,肌筋膜炎28例,皮下结缔组织炎9例,皮肤增厚4例。肌肉水肿1级16例、2级24例、3级9例;肌肉水肿2级组肌酶水平均较另两组高,但仅AST与另两组的差异有统计学意义(P<0.05)。结论磁共振成像易检出皮肌炎肌肉水肿等肌肉损害,有助于判断疾病严重程度及累及范围;皮肌炎患儿肌肉水肿程度与肌酶水平不平行。
