Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the se...Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index （BMI） 24 kg/m2 and visceral fat area （VFA） 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females （81.75 cm）. Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.展开更多
基金supported by the Major Science and Technology Project of Zhejiang Province(Grant NO.2009C03010-4)the National Key Technology R&D Program of China(Grants No.2012BAI02B03 and No.2009BAI80B00)
文摘Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index （BMI） 24 kg/m2 and visceral fat area （VFA） 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females （81.75 cm）. Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.
