An anomalous resistance drop was observed near 190K in the R-T measurement on a sample in Bi-Sr-Ca-Cu-O system and the transition completed at 80K.After keeping the sample at room temperature for 10h,the temperature d...An anomalous resistance drop was observed near 190K in the R-T measurement on a sample in Bi-Sr-Ca-Cu-O system and the transition completed at 80K.After keeping the sample at room temperature for 10h,the temperature dependence of the resistance changed from semiconducting to metallic behavior,while the ending of the transition remained at 80K.This might be an evidence of the existence of a metastable superconducting phase in Bi-Sr-Ca-Cu-O system with Tc as high as 190K.展开更多
CLIMATE change is a major global challenge facing the world today. It relates to the survival of the human beings and the development of all countries,
A two-moment (mass and number) warm cloud scheme together with ground and aircraft measurements over Beijing is used in a regional model to study the effects of aerosols on cloud radiative property and precipitation.U...A two-moment (mass and number) warm cloud scheme together with ground and aircraft measurements over Beijing is used in a regional model to study the effects of aerosols on cloud radiative property and precipitation.Using a prescribed tri-modal lognormal aerosol size distribution,the aerosol numbers are calculated from prognostic aerosol masses,for which advection,diffusion,and cloud drop activation/deactivation are considered.Specifically,the accumulation mode of a tri-lognormal aerosol size distribution is fitted to the aircraft measured values for a cold front case passed through northern China during June 25-26,2005.In the simulations,the warm cloud scheme simulates explicitly the cloud drops and subsequently affects the radiative heating and cooling,and circulations.Simulations with different initial conditions for being fitted with aircraft measurements,continental and maritime aerosol numbers were conducted.It is found that more aerosols result in more but smaller cloud drops and more cloud water,leading to an increase in albedo.The effects on rains are complex:smaller cloud drops have less efficient coagulation for raindrop to form (autoconversion),leading to fewer raindrop numbers and less rainwater;while more cloud water enhances the accretion for raindrop growth.Nevertheless,for the whole cloud system,the impact of increasing aerosols inhibits precipitation.展开更多
The binding of recombinant human macrophage colony-stimulating factor (M-CSF) soluble receptor (rh-M-CSF-sR) to membrane-bound macrophage colony stimulating factor (m-M-CSF) and the internalization and recycling of rh...The binding of recombinant human macrophage colony-stimulating factor (M-CSF) soluble receptor (rh-M-CSF-sR) to membrane-bound macrophage colony stimulating factor (m-M-CSF) and the internalization and recycling of rh-M-CSF-sR/m-M-CSF complexes mediated by m-M-CSF were studied with a model of J6-1 cell line. The results indicated that m-M-CSF bound rh-M-CSF-sR with high affinity (Kd= 1.78×10 12 mol/L) and mediated a temperature- and energy-dependent internalization of rh-M-CSF-sR, and that internalized rh-M-CSF-sR could return to the cell surface in an m-M-CSF-bound state, suggesting that m-M-CSF may have a capability to mediate the internalization and recycling of rh-M-CSF-sR/m-M-CSF complexes. In addition, the half-lives of cell-associated M-CSF and its receptor of stimulated normal human cord blood mononuclear cells (CBMCs) and 4 leukemic cell lines were measured by indirect immunoflu-orescence and flow cytometry. The results showed that the half-lives of the various kinds of M-CSF isoforms and展开更多
According to the definition of cytokine, the direction of signaling should be from cytokine to receptor. The counter receptor was presented. Membrane bound macrophage colony-stimulating factor (m-M-CSF) and its recept...According to the definition of cytokine, the direction of signaling should be from cytokine to receptor. The counter receptor was presented. Membrane bound macrophage colony-stimulating factor (m-M-CSF) and its receptor (M-CSF-R) were shown in human leukemic cell line J6-1 as autojuxtacrine mechanism. Soluble M-CSF receptor (sM-CSF-R), which was isolated from J6-1 cells membrane, was added into J6-1 cell culture. It was observed inhibition of J6-1 cell proliferation, decreasing of mitosis index and ratio of multinuclear cells, enlargement of cell diameter and volume, down regulation of numerous surface antigens. Dramatic change of intracellular pH was shown between several min to 20 min after treatment of sM-CSF-R. It suggested that some information was transmitted via m-M-CSF from sM-CSF-R. This counter signaling was not influenced by saccharification of m-M-CSF.展开更多
China’s top meteorologist talks about the Copenhagen Accord The UN Climate Change Conference concluded on the afternoon of December 19 in Copenhagen,Denmark.The scale of the meeting and the attention it has attracted...China’s top meteorologist talks about the Copenhagen Accord The UN Climate Change Conference concluded on the afternoon of December 19 in Copenhagen,Denmark.The scale of the meeting and the attention it has attracted speak to its great importance.展开更多
基金Project suppprted by the Naticma J.Science Foundstion of China(No.1860860)and the Chinese Superconducting Research Center.
文摘An anomalous resistance drop was observed near 190K in the R-T measurement on a sample in Bi-Sr-Ca-Cu-O system and the transition completed at 80K.After keeping the sample at room temperature for 10h,the temperature dependence of the resistance changed from semiconducting to metallic behavior,while the ending of the transition remained at 80K.This might be an evidence of the existence of a metastable superconducting phase in Bi-Sr-Ca-Cu-O system with Tc as high as 190K.
文摘CLIMATE change is a major global challenge facing the world today. It relates to the survival of the human beings and the development of all countries,
基金supported by the National Key Technology R&D Program of China(Grant No. 2006BAC12B01)the National Natural Science Foundation of China (Grant No. 40533015)
文摘A two-moment (mass and number) warm cloud scheme together with ground and aircraft measurements over Beijing is used in a regional model to study the effects of aerosols on cloud radiative property and precipitation.Using a prescribed tri-modal lognormal aerosol size distribution,the aerosol numbers are calculated from prognostic aerosol masses,for which advection,diffusion,and cloud drop activation/deactivation are considered.Specifically,the accumulation mode of a tri-lognormal aerosol size distribution is fitted to the aircraft measured values for a cold front case passed through northern China during June 25-26,2005.In the simulations,the warm cloud scheme simulates explicitly the cloud drops and subsequently affects the radiative heating and cooling,and circulations.Simulations with different initial conditions for being fitted with aircraft measurements,continental and maritime aerosol numbers were conducted.It is found that more aerosols result in more but smaller cloud drops and more cloud water,leading to an increase in albedo.The effects on rains are complex:smaller cloud drops have less efficient coagulation for raindrop to form (autoconversion),leading to fewer raindrop numbers and less rainwater;while more cloud water enhances the accretion for raindrop growth.Nevertheless,for the whole cloud system,the impact of increasing aerosols inhibits precipitation.
文摘The binding of recombinant human macrophage colony-stimulating factor (M-CSF) soluble receptor (rh-M-CSF-sR) to membrane-bound macrophage colony stimulating factor (m-M-CSF) and the internalization and recycling of rh-M-CSF-sR/m-M-CSF complexes mediated by m-M-CSF were studied with a model of J6-1 cell line. The results indicated that m-M-CSF bound rh-M-CSF-sR with high affinity (Kd= 1.78×10 12 mol/L) and mediated a temperature- and energy-dependent internalization of rh-M-CSF-sR, and that internalized rh-M-CSF-sR could return to the cell surface in an m-M-CSF-bound state, suggesting that m-M-CSF may have a capability to mediate the internalization and recycling of rh-M-CSF-sR/m-M-CSF complexes. In addition, the half-lives of cell-associated M-CSF and its receptor of stimulated normal human cord blood mononuclear cells (CBMCs) and 4 leukemic cell lines were measured by indirect immunoflu-orescence and flow cytometry. The results showed that the half-lives of the various kinds of M-CSF isoforms and
文摘According to the definition of cytokine, the direction of signaling should be from cytokine to receptor. The counter receptor was presented. Membrane bound macrophage colony-stimulating factor (m-M-CSF) and its receptor (M-CSF-R) were shown in human leukemic cell line J6-1 as autojuxtacrine mechanism. Soluble M-CSF receptor (sM-CSF-R), which was isolated from J6-1 cells membrane, was added into J6-1 cell culture. It was observed inhibition of J6-1 cell proliferation, decreasing of mitosis index and ratio of multinuclear cells, enlargement of cell diameter and volume, down regulation of numerous surface antigens. Dramatic change of intracellular pH was shown between several min to 20 min after treatment of sM-CSF-R. It suggested that some information was transmitted via m-M-CSF from sM-CSF-R. This counter signaling was not influenced by saccharification of m-M-CSF.
文摘China’s top meteorologist talks about the Copenhagen Accord The UN Climate Change Conference concluded on the afternoon of December 19 in Copenhagen,Denmark.The scale of the meeting and the attention it has attracted speak to its great importance.
