With the rapid development of social economy,transportation has become faster and more efficient.As an important part of goods transportation,the safe maintenance of tunnel highways has become particularly important.T...With the rapid development of social economy,transportation has become faster and more efficient.As an important part of goods transportation,the safe maintenance of tunnel highways has become particularly important.The maintenance of tunnel roads has become more difficult due to problems such as sealing,narrowness and lack of light.Currently,target detection methods are advantageous in detecting tunnel vehicles in a timely manner through monitoring.Therefore,in order to prevent vehicle misdetection and missed detection in this complex environment,we propose aYOLOv5-Vehicle model based on the YOLOv5 network.This model is improved in three ways.Firstly,The backbone network of YOLOv5 is replaced by the lightweight MobileNetV3 network to extract features,which reduces the number of model parameters;Next,all convolutions in the neck module are improved to the depth-wise separable convolutions to further reduce the number of model parameters and computation,and improve the detection speed of the model;Finally,to ensure the accuracy of the model,the CBAM attention mechanism is introduced to improve the detection accuracy and precision of the model.Experiments results demonstrate that the YOLOv5-Vehicle model can improve the accuracy.展开更多
目的:探讨健脾清肠方(JPQCD)含药血清对HT29细胞内质网应激(ERS)模型NF-κB信号通路的影响健脾清肠方。方法:采用毒胡萝卜素内酯(Tg)诱导体外HT29细胞发生ERD,分为空白组(Control组),模型组(Model组)及健脾清肠方含药血清低、高浓度组(J...目的:探讨健脾清肠方(JPQCD)含药血清对HT29细胞内质网应激(ERS)模型NF-κB信号通路的影响健脾清肠方。方法:采用毒胡萝卜素内酯(Tg)诱导体外HT29细胞发生ERD,分为空白组(Control组),模型组(Model组)及健脾清肠方含药血清低、高浓度组(JPQCD-L组、JPQCD-H组)。用健脾清肠方含药血清干预后,Western Blot法和Real time PCR法检测HT29细胞中GRP78、NF-κB蛋白及mRNA表达。结果:与Control组比较,Model组GRP78、NF-κB蛋白及mRNA表达均增加(P<0.05);与Model组比较,JPQCD-L组和JPQCD-H组GRP78、NF-κB蛋白及mRNA表达均减少(P<0.05);与JPQCD-L组比较,JPQCD-H组GRP78、NF-κB蛋白及其mRNA表达减少(P<0.05)。结论:健脾清肠方含药血清能抑制Tg诱导体外HT29细胞发生ERS,抑制NF-κB信号通路,发挥其消炎的作用。展开更多
文摘With the rapid development of social economy,transportation has become faster and more efficient.As an important part of goods transportation,the safe maintenance of tunnel highways has become particularly important.The maintenance of tunnel roads has become more difficult due to problems such as sealing,narrowness and lack of light.Currently,target detection methods are advantageous in detecting tunnel vehicles in a timely manner through monitoring.Therefore,in order to prevent vehicle misdetection and missed detection in this complex environment,we propose aYOLOv5-Vehicle model based on the YOLOv5 network.This model is improved in three ways.Firstly,The backbone network of YOLOv5 is replaced by the lightweight MobileNetV3 network to extract features,which reduces the number of model parameters;Next,all convolutions in the neck module are improved to the depth-wise separable convolutions to further reduce the number of model parameters and computation,and improve the detection speed of the model;Finally,to ensure the accuracy of the model,the CBAM attention mechanism is introduced to improve the detection accuracy and precision of the model.Experiments results demonstrate that the YOLOv5-Vehicle model can improve the accuracy.
文摘目的:探讨健脾清肠方(JPQCD)含药血清对HT29细胞内质网应激(ERS)模型NF-κB信号通路的影响健脾清肠方。方法:采用毒胡萝卜素内酯(Tg)诱导体外HT29细胞发生ERD,分为空白组(Control组),模型组(Model组)及健脾清肠方含药血清低、高浓度组(JPQCD-L组、JPQCD-H组)。用健脾清肠方含药血清干预后,Western Blot法和Real time PCR法检测HT29细胞中GRP78、NF-κB蛋白及mRNA表达。结果:与Control组比较,Model组GRP78、NF-κB蛋白及mRNA表达均增加(P<0.05);与Model组比较,JPQCD-L组和JPQCD-H组GRP78、NF-κB蛋白及mRNA表达均减少(P<0.05);与JPQCD-L组比较,JPQCD-H组GRP78、NF-κB蛋白及其mRNA表达减少(P<0.05)。结论:健脾清肠方含药血清能抑制Tg诱导体外HT29细胞发生ERS,抑制NF-κB信号通路,发挥其消炎的作用。
