This paper primarily concerns the effective coordination of the procedures and methods employed in open pit mining operations under the background of river management.The central objective of this study is to identify...This paper primarily concerns the effective coordination of the procedures and methods employed in open pit mining operations under the background of river management.The central objective of this study is to identify a viable approach for ensuring rational and efficient development of open pit mineral resources while simultaneously protecting and restoring the ecological environment of the river.This approach should facilitate the realization of a harmonious symbiosis between mining and river management.The intricate mutual influence relationship between river management and open pit mining is first analyzed in depth,which provides a solid foundation for the subsequent coordination strategy development.In light of the aforementioned considerations,a set of coordination procedures for open pit mining based on river management conditions is proposed.These procedures emphasize the integration of river protection into the overall layout of mining at the planning stage.The implementation of scientific mining schemes,accompanied by rigorous control of the scope and depth of mining operations,has proven to be an effective means of reducing the impact of mining activities on river environments.This approach has also facilitated the achievement of a balance and coordination between mining and river management.展开更多
合成了一种新型阻燃剂六-(N-羟乙基氨基-DOPO-次甲基-苯氧基)-环三磷腈(HEACTP-DOPO),利用傅里叶变换红外光谱(FT-IR)、核磁共振波谱(1H-NMR、31P-NMR)和高分辨质谱(HRMS)确定了其结构,并将HEACTP-DOPO和二乙基次膦酸铝(ADP)复配用于环...合成了一种新型阻燃剂六-(N-羟乙基氨基-DOPO-次甲基-苯氧基)-环三磷腈(HEACTP-DOPO),利用傅里叶变换红外光谱(FT-IR)、核磁共振波谱(1H-NMR、31P-NMR)和高分辨质谱(HRMS)确定了其结构,并将HEACTP-DOPO和二乙基次膦酸铝(ADP)复配用于环氧树脂DGEBA阻燃研究。采用极限氧指数(LOI)和垂直燃烧(UL-94)、热重分析(TGA)和锥形量热(Cone)研究了材料的热降解行为和阻燃性能。当100 g DGEBA中添加10 g HEACTP-DOPO和3 g ADP时,所得阻燃材料的LOI值为37.0%,垂直燃烧通过UL-94V-0级;TGA分析表明,阻燃材料能降低环氧树脂的初始降解温度,增加了高温时的残炭量;Cone数据计算发现,该阻燃材料与纯环氧树脂相比,热释放速率峰值(PHRR)、总热释放(THR)、平均有效燃烧热(Av-EHC)和烟释放总量(TSP)分别降低了39.9%,42.6%,57.6%和7.5%。扫描电镜(SEM)和Mapping结果表明,阻燃材料燃烧后,大量N,P和Al元素分布在致密炭层中,起到了良好的凝聚相阻燃作用。展开更多
To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensio...To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensional numerical model of the XBeach beach profile.By numerically modeling the change in the nourished profile for different dry beach widths under normal waves and storm conditions and the recovery process of the profile after the storm,the degree of response in dry beach nourishment for the fully dissipative beach is analyzed.The results show that under normal wave conditions,the response of the nourished dry beach is obvious.Sediment on the dry beach erodes heavily,and the shoreline moves landward over a long distance.With the increase in the width and size of the dry beach,the wave height at the bottom of the backshore profile decreases,the wave height attenuation rate increases continuously,and the wave elimination effect is remarkable.When the storm incident wave intensifies,the wave height attenuation rate of the nourished dry beach decreases,indicating that the smaller the storm intensity is,the more significant the wave reduction effect of the nourished dry beach is.At the same time,different profile arrangements of nourished dry beaches suffer from different degrees of erosion under storm conditions,with significant changes in profile morphology.With intensified storm action,the intensity of sediment erosion in the nourished dry beach increases,the nourishment is weakened,and the recovery effect of the profile after the storm is not obvious.The results of the numerical modeling highlight that the dry beach nourishment method can resist storms to a certain extent,but the overall effect is relatively limited.展开更多
An infrared solar spectrum observed by ground-based telescopes is seriously affected by the background radiation both from the telescope and sky,relative to the visible wavelengths.Its accuracy is also influenced by t...An infrared solar spectrum observed by ground-based telescopes is seriously affected by the background radiation both from the telescope and sky,relative to the visible wavelengths.Its accuracy is also influenced by the spectral resolution of the Fourier transform spectrometer.In the paper,we developed a CO_(2)gas cell and installed it in the sample compartment to calibrate the spectral resolution of the Bruker IFS-125HR at infrared wavelengths.The measured spectral resolution is 0.00342±0.00086 cm^(-1)and 0.0059±0.00024 cm^(-1)at the wavenumbers of798 cm^(-1)and 2136 cm^(-1),respectively.We also updated a fully reflective sunlight feeding system to observe the solar spectrum near CO 4.66μm and Mg I 12.32μm.By quickly pointing the sunlight feeding system about1 degree away from the solar disk center,we are able to measure the background radiation from the telescope and the sky at Huairou Solar Observing Station.After removing the background radiation,our observed solar spectrum at CO 4.66μm is consistent with that from the National Solar Observatory.The Mg I 12.32μm working line selected by the Accurate Infrared Magnetic Field Measurements of the Sun(AIMS)project is also identified.Our method is helpful not only for the spectral resolution calibration and background radiation correction of AIMS but also for other infrared astronomical telescopes.展开更多
How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central A...How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central Asian Orogenic Belt(CAOB) in Northwest China,offer a special natural laboratory to resolve this puzzle.In the Chinese Altay,the Erqis unit consists of ophiolitic melanges and coherent assemblages,forming a Paleozoic accretionary complex.At least two ophiolitic melanges(Armantai,and Kelameili) in East Junggar,characterized by imbricated ophiolitic melanges,Nb-enriched basalts,adakitic rocks and volcanic rocks,belong to a Devonian-Carboniferous intra-oceanic island arc with some Paleozoic ophiolites,superimposed by Permian arc volcanism.In the Tianshan,ophiolitic melanges like Kanggurtag,North Tianshan,and South Tianshan occur as part of some Paleozoic accretionary complexes related to amalgamation of arc terranes.In the Beishan there are also several ophiolitic melanges,including the Hongshishan,Xingxingxia-Shibangjing,Hongliuhe-Xichangjing,and Liuyuan ophiolitic units.Most ophiolitic melanges in the study area are characterized by ultramafic,mafic and other components,which are juxtaposed,or even emplaced as lenses and knockers in a matrix of some coherent units.The tectonic settings of various components are different,and some adjacent units in the same melange show contrasting different tectonic settings.The formation ages of these various components are in a wide spectrum,varying from Neoproterozoic to Permian.Therefore we cannot assume that these ophiolitic melanges always form in linear sutures as a result of the closure of specific oceans.Often the ophiolitic components formed either as the substrate of intra-oceanic arcs,or were accreted as lenses or knockers in subduction-accretion complexes.Using published age and paleogeographic constraints,we propose the presence of (1) a major early Paleozoic tectonic boundary that separates the Chinese Altay-East Junggar multiple subduction systems of the southern Siberian active margin from those of the northern Tarim;and (2) a major Permian suture zone that separates the Tianshan-Beishan from the northern active margin of the Tarim Craton.These new observations and interpretations have broad implications for the architecture and crustal growth of central Asia and other ancient orogens as well.展开更多
Tarim Precambrian bedrocks are well exposed in the Kuluketage and Aksu areas, where twenty four samples were taken to reveal the denudation history of the northern Tarim Craton. Apatite fission track dating and therma...Tarim Precambrian bedrocks are well exposed in the Kuluketage and Aksu areas, where twenty four samples were taken to reveal the denudation history of the northern Tarim Craton. Apatite fission track dating and thermal history modeling suggest that the northern Tarim experienced multi-stage cooling events which were assumed to be associated with the distant effects of the Cimmerian orogeny and India-Eurasia collision in the past. But the first episode of exhumation in the northern Tarim, occurring in the mid-Permian to Triassic, is here suggested to be induced by docking of the Tarim Craton and final amalgamation of the Central Asian Orogenic Belt. The cooling event at ca. 170 Ma may be triggered by the Qiangtang-Eurasia collision. Widespread Cretaceous exhumation could be linked with docking of the Lhasa terrane in the late Jurassic. Cenozoic reheating and recooling likely occurred because of the northpropagating stress, however, this has not affected the northern Tarim much because the Tarim is characterized by rigid block-like motion.展开更多
The Hongyanjing inter-arc basin, is located at the central part of Beishan Orogenic College (BOC), Gansu Province, northwest China. Thick sequences of Permian sediments were strongly folded, forming extremely specta...The Hongyanjing inter-arc basin, is located at the central part of Beishan Orogenic College (BOC), Gansu Province, northwest China. Thick sequences of Permian sediments were strongly folded, forming extremely spectacular superposed folds. To better understand the thermal history of Hongyanjing interarc basin and to potentially constrain the timing of deformation, apatite fission track thermochronology method was applied on two superposed folds in the Hongyanjing Basin. Samples from the basin, yield central AFT ages ranging from - 206 to 118 Ma. AFT peak ages were largely consistent between samples and can divided into three groups: 245, 204-170 and 112-131 Ma. Subsequent thermal history modeling of the samples from the Hongyanjing Basin can be summarized as follows: (1) thermal reheating by sedimentary burial at - 260 to -220 Ma; (2) major cooling from -220 to -180 Ma; (3) an episode of very slow subsequent cooling from -180 to 65 Ma (-80 ℃) to present-day outcrop temperatures. Sediments in the Hongyanjing Basin were folded forming F1 fold during the early to late Triassic (-240--220 Ma), by regional stress, and at the time that the adjacent Xingxingxia shear zone started to become active. It is further suggested that the F2 folding occurred at -225-219 Ma. The deformation age of F2 should he extended to 180 Ma based on our thermal history modeling for the Hongyanjing Basin, which show a rapid exhumation and cooling at the late Triassic to early Jurassic (-220-- 180 Ma). In our interpretations, the F1 folding is therefore thought to he related to the final closure of the Paleo-Asian Ocean, while the F2 folding occurred at - 225-180 Ma associated with a major pulse of orogenesis in the BOC.展开更多
Background Ultrasound-guided continuous thoracic paravertebral block can provide pain-relieving and opioid-sparing effects in patients receiving open hepatectomy.We hypothesize that these effects may improve the quali...Background Ultrasound-guided continuous thoracic paravertebral block can provide pain-relieving and opioid-sparing effects in patients receiving open hepatectomy.We hypothesize that these effects may improve the quality of recovery(QoR)after open hepatectomy.Methods Seventy-six patients undergoing open hepatectomy were randomized to receive a continuous thoracic paravertebral block with ropivacaine(CTPVB group)or normal saline(control group).All patients received patient-controlled intravenous analgesia with morphine postoperatively for 48 hours.The primary outcome was the global Chinese 15-item Quality of Recovery score on postoperative day 7,which was statistically analyzed using Student’s t-test.Results Thirty-six patients in the CTPVB group and 37 in the control group completed the study.Compared to the control group,the CTPVB group had significantly increased global Chinese 15-item Quality of Recovery scores(133.14±12.97 vs.122.62±14.89,P=0.002)on postoperative day 7.Postoperative pain scores and cumulative morphine consumption were significantly lower for up to 8 and 48 hours(P<0.05;P=0.002),respectively,in the CTPVB group.Conclusion Perioperative CTPVB markably promotes patient’s QoR after open hepatectomy with a profound analgesic effect in the early postoperative period.展开更多
This study evaluated the effects of worm infection on the volatile components,total phenolic compounds,and antioxidant capacities of Gomphidius rutilus.G.rutilus without worms(GW),G.rutilus infected by a small amount ...This study evaluated the effects of worm infection on the volatile components,total phenolic compounds,and antioxidant capacities of Gomphidius rutilus.G.rutilus without worms(GW),G.rutilus infected by a small amount of worms(GS;infected area<50%),and G.rutilus infected by a large amount of worms(GL;infected area>50%)were investigated.The volatile components of G.rutilus were analyzed by simultaneous distillation–extraction(SDE)and headspace solid-phase microextraction(HS-SPME)using gas chromatography–mass spectrometry(GC–MS).A total of 17 and 19 types of volatile compounds were detected,including ketones,alcohols,benzene,alkenes,aldehydes,esters,acids,and alkanes.Alcohols comprised the most abundant compound in GL,GS,and GW.The relative content of 1-octen-3-ol was the highest in all mushrooms.The concentration of eight-carbon(C8)compounds relative to the total volatile compounds varied widely,ranging from 40%(GW)to 64.34%(GS)and 84.42%(GS)and to 91.59%(GL),respectively,among the three samples.The antioxidant capability and the total phenolic contents of G.rutilus were evaluated in this study.The highest total phenolic content(TPC)of 192.23 mg GAE/g was found in GL,which differed significantly(P<0.05)from the latter two samples,whereas the lowest value of 156.11 mg GAE/g was found in GW.ABTS radical cation scavenging activity,FRAP ferric reducing antioxidant capacity(FRAP)radical scavenging activity,and oxygen radical absorbance capacity(ORAC)were investigated to screen the antioxidant properties of extracts.The contents of total phenolic compounds and their antioxidant capacities in vitro showed significant correlations(P<0.01).Among the three types of samples,the phenolic compounds of GL exhibited the highest antioxidant capacity,showing the values of 0.089 mM TE/g for ABTS,0.949 mM Fe^2+E/g for FRAP,and 1.952 M TE/g for ORAC.However,regarding the total antioxidant capacity,GS exhibited the highest antioxidant capacity,showing the values of 0.002648 mM TE/g for ABTS,0.004437 mM Fe^2+E/g for FRAP,and 0.256μM TE/g for ORAC.In conclusion,HS-SPME was more suitable for the extraction of volatile aroma components from G.rutilus.GL had the most abundant aroma components.GL had the highest TPC and antioxidant capacity compared with those of GS and GW,whereas GS showed the opposite results.Interestingly,GS was found to have the highest total antioxidant capacity in vitro.Based on these measured indicators,worm infection had no negative effect on the quality of G.rutilus.Therefore,worm-infected G.rutilus can also be consumed by humans.展开更多
An infrared (IR) imaging simulation framework based on the strap-down platform is proposed for midcourse ballistic targets. It overcomes the shortcoming of the existing algorithms, which cannot simulate IR imaging f...An infrared (IR) imaging simulation framework based on the strap-down platform is proposed for midcourse ballistic targets. It overcomes the shortcoming of the existing algorithms, which cannot simulate IR imaging from the entire midcourse process. The proposed framework includes three steps, target characteristic modeling, motion modeling, and imaging modeling. In imaging modeling, the staring focal plane is taken into account due to its wide employment. In order to obtain IR images of high fidelity, especially that the fluctuation of the target signal-to-noise ratio (SNR) is reasonably similar to the actual one, this paper proposes an improved IR imaging simulation method. The proposed method considers two critical factors of the pixel plane, occupy-empty ratio and defect elements, which affect the imaging of targets markedly but are neglected in previous work. Finally, the IR image sequence of high fidelity is obtained. And the correlative parameters of simulation can be set according to the given scene. Thus the generated images can satisfy the needs of algorithms validation for tracking and recognition.展开更多
OBJECTIVE Vertebral metastases are a common manifestation in patients with advanced cancer and treatment is often ineffective. This study was conducted to explore the efficacy of treating vertebral metastases by percu...OBJECTIVE Vertebral metastases are a common manifestation in patients with advanced cancer and treatment is often ineffective. This study was conducted to explore the efficacy of treating vertebral metastases by percutaneous vertebroplasty (PVP) combined with interventional chemotherapy. METHODS Seventy-five patients with vertebral metastases (42 men, 33 women; ages 31-76 years) were divided into 2 groups: 39 cases were treated by PVP combined with chemotherapy (VPCC group), and 36 cases were treated by PVP alone (VP group). All procedures were guided by computed tomography (CT) scanning. The results and complications were evaluated by a questionnaire regarding pain and routine follow-up. RESULTS The response rate was significantly higher in the VPCC group than in the VP group (93.0% vs 74.4%, P〈0.05); total response rates for the VPCC and VP groups were 25.6% and 10.3% respectively. A common complication related to VPCC was transient aggravating pain. CONCLUSION PVP may ameliorate pain, and consolidate the vertebrae of patients with vertebral metastases. Its short-term effect may be enhanced by adding drugs into the bone cement.展开更多
The influence of mild hypothermia on neural cell apoptosis remains poorly understood. Therefore, the present study established rat models of diffuse axonal injury (DAI) at 33℃. Morris water maze results demonstrate...The influence of mild hypothermia on neural cell apoptosis remains poorly understood. Therefore, the present study established rat models of diffuse axonal injury (DAI) at 33℃. Morris water maze results demonstrated significantly better learning and memory functions in DAI rats with hypothermia compared with DAI rats with normothermia. Expression of apoptotic protease activating factor-1 in the hippocampal CA1 region was significantly lower in the DAI hypothermia group compared with the DAI normothermia group. Expression of apoptotic protease activating factor-1 positively correlated with latency, but negatively correlated with platform location times and time of swimming in the quadrant area. Results suggested that post-traumatic mild hypothermia in a rat model of DAI could provide cerebral protection by attenuating expression of apoptotic protease activating factor-1.展开更多
:Colorectal cancer(CRC)is a heterogeneous cancer,and many risk factors for colorectal cancer have been established.For CRC metastasis,tumor cell migration,adhesion as well as invasion are important processes.Wiskott-A...:Colorectal cancer(CRC)is a heterogeneous cancer,and many risk factors for colorectal cancer have been established.For CRC metastasis,tumor cell migration,adhesion as well as invasion are important processes.Wiskott-Aldrich syndrome protein family member 3(WASF3)is necessary for metastasis of various types of cancers.However,its role in CRC progression has not been fully elucidated.This study examined the in vitro functional roles of WASF3 in the CRC and explored the underlying molecular mechanisms.We used siRNA-WASF3 to gene silence WASF3 in colon cancer cell(HCT116)in vitro.The effects of WASF3 silencing on HCT116 cell apoptosis,proliferation,migration,as well as invasion were assessed by flow cytometry,CCK-8,and transwell assays.ZNF471 protein expressions were detected by immunofluorescence staining and RT-PCR.Moreover,the effects of ZNF471 were studied on a series of in vitro antitumor-promoting assays using HCT116.WASF3 knockdown expression using small interfering RNA(siRNA)ameliorated CRC cell proliferation,anchorage-independent growth,invasion,and metastasis.Furthermore,we observed that WASF3 contributed to upregulating the metastasis signaling pathway through inhibiting the expression of ZNF471.Our study suggests that targeting WASF3 signaling might be a novel therapeutic strategy for treating CRC.展开更多
The steady-state and transient electron transport properties ofβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructures were investigated by Monte Carlo simulation with the classic three-valley model.In particular,the...The steady-state and transient electron transport properties ofβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructures were investigated by Monte Carlo simulation with the classic three-valley model.In particular,the electronic band structures were acquired by first-principles calculations,which could provide precise parameters for calculating the transport properties of the two-dimensional electron gas(2DEG),and the quantization effect was considered in theΓvalley with the five lowest subbands.Wave functions and energy eigenvalues were obtained by iteration of the Schrödinger–Poisson equations to calculate the 2DEG scattering rates with five main scattering mechanisms considered.The simulated low-field electron mobilities agree well with the experimental results,thus confirming the effectiveness of our models.The results show that the room temperature electron mobility of theβ-(Al_(0.188)Ga_(0.812))_(2)O_(3)/Ga_(2)O_(3)heterostructure at 10 k V·cm^(-1)is approximately153.669 cm^(2)·V^(-1)·s^(-1),and polar optical phonon scattering would have a significant impact on the mobility properties at this time.The region of negative differential mobility,overshoot of the transient electron velocity and negative diffusion coefficients are also observed when the electric field increases to the corresponding threshold value or even exceeds it.This work offers significant parameters for theβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructure that may benefit the design of high-performanceβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructure-based devices.展开更多
Ventricular tachycardia storm (VTS) is defined as a life-threatening syndrome of three or more separate episodes of ventricular tachycardia (VT) leading to implantable cardioverter defibrillator (ICD) therapy wi...Ventricular tachycardia storm (VTS) is defined as a life-threatening syndrome of three or more separate episodes of ventricular tachycardia (VT) leading to implantable cardioverter defibrillator (ICD) therapy within 24 hours. Patients with VTS have poor outcomes and require immediate medical attention. ICD shocks have been shown to be associated with increased mortality in several studies. Optimal programming in minimization of ICD shocks may decrease mortality. Large controlled trials showed that long detection time and high heart rate detection threshold reduced ICD shock burden without an increase in syncope or death. As a fundamental therapy of ICD, anti- tachycardia pacing (ATP) can terminate most slow VT with a low risk of acceleration. For fast VT, burst pacing is more effective and less likely to result in acceleration than ramp pacing. One algorithm of optimal programming management during a VTS is presented in the review.展开更多
文摘This paper primarily concerns the effective coordination of the procedures and methods employed in open pit mining operations under the background of river management.The central objective of this study is to identify a viable approach for ensuring rational and efficient development of open pit mineral resources while simultaneously protecting and restoring the ecological environment of the river.This approach should facilitate the realization of a harmonious symbiosis between mining and river management.The intricate mutual influence relationship between river management and open pit mining is first analyzed in depth,which provides a solid foundation for the subsequent coordination strategy development.In light of the aforementioned considerations,a set of coordination procedures for open pit mining based on river management conditions is proposed.These procedures emphasize the integration of river protection into the overall layout of mining at the planning stage.The implementation of scientific mining schemes,accompanied by rigorous control of the scope and depth of mining operations,has proven to be an effective means of reducing the impact of mining activities on river environments.This approach has also facilitated the achievement of a balance and coordination between mining and river management.
文摘合成了一种新型阻燃剂六-(N-羟乙基氨基-DOPO-次甲基-苯氧基)-环三磷腈(HEACTP-DOPO),利用傅里叶变换红外光谱(FT-IR)、核磁共振波谱(1H-NMR、31P-NMR)和高分辨质谱(HRMS)确定了其结构,并将HEACTP-DOPO和二乙基次膦酸铝(ADP)复配用于环氧树脂DGEBA阻燃研究。采用极限氧指数(LOI)和垂直燃烧(UL-94)、热重分析(TGA)和锥形量热(Cone)研究了材料的热降解行为和阻燃性能。当100 g DGEBA中添加10 g HEACTP-DOPO和3 g ADP时,所得阻燃材料的LOI值为37.0%,垂直燃烧通过UL-94V-0级;TGA分析表明,阻燃材料能降低环氧树脂的初始降解温度,增加了高温时的残炭量;Cone数据计算发现,该阻燃材料与纯环氧树脂相比,热释放速率峰值(PHRR)、总热释放(THR)、平均有效燃烧热(Av-EHC)和烟释放总量(TSP)分别降低了39.9%,42.6%,57.6%和7.5%。扫描电镜(SEM)和Mapping结果表明,阻燃材料燃烧后,大量N,P和Al元素分布在致密炭层中,起到了良好的凝聚相阻燃作用。
基金The National Natural Science Foundation of China under contract No.41930538the Scientific Research Foundation of the Third Institute of Oceanography,Ministry of Natural Resources under contract No.2022017。
文摘To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensional numerical model of the XBeach beach profile.By numerically modeling the change in the nourished profile for different dry beach widths under normal waves and storm conditions and the recovery process of the profile after the storm,the degree of response in dry beach nourishment for the fully dissipative beach is analyzed.The results show that under normal wave conditions,the response of the nourished dry beach is obvious.Sediment on the dry beach erodes heavily,and the shoreline moves landward over a long distance.With the increase in the width and size of the dry beach,the wave height at the bottom of the backshore profile decreases,the wave height attenuation rate increases continuously,and the wave elimination effect is remarkable.When the storm incident wave intensifies,the wave height attenuation rate of the nourished dry beach decreases,indicating that the smaller the storm intensity is,the more significant the wave reduction effect of the nourished dry beach is.At the same time,different profile arrangements of nourished dry beaches suffer from different degrees of erosion under storm conditions,with significant changes in profile morphology.With intensified storm action,the intensity of sediment erosion in the nourished dry beach increases,the nourishment is weakened,and the recovery effect of the profile after the storm is not obvious.The results of the numerical modeling highlight that the dry beach nourishment method can resist storms to a certain extent,but the overall effect is relatively limited.
基金supported by the National Key R&D Program of China(2021YFA1600500)the Youth Innovation Promotion Association CAS(2023061)the National Natural Science Foundation of China(NSFC,Grant Nos.12003051,11427901)。
文摘An infrared solar spectrum observed by ground-based telescopes is seriously affected by the background radiation both from the telescope and sky,relative to the visible wavelengths.Its accuracy is also influenced by the spectral resolution of the Fourier transform spectrometer.In the paper,we developed a CO_(2)gas cell and installed it in the sample compartment to calibrate the spectral resolution of the Bruker IFS-125HR at infrared wavelengths.The measured spectral resolution is 0.00342±0.00086 cm^(-1)and 0.0059±0.00024 cm^(-1)at the wavenumbers of798 cm^(-1)and 2136 cm^(-1),respectively.We also updated a fully reflective sunlight feeding system to observe the solar spectrum near CO 4.66μm and Mg I 12.32μm.By quickly pointing the sunlight feeding system about1 degree away from the solar disk center,we are able to measure the background radiation from the telescope and the sky at Huairou Solar Observing Station.After removing the background radiation,our observed solar spectrum at CO 4.66μm is consistent with that from the National Solar Observatory.The Mg I 12.32μm working line selected by the Accurate Infrared Magnetic Field Measurements of the Sun(AIMS)project is also identified.Our method is helpful not only for the spectral resolution calibration and background radiation correction of AIMS but also for other infrared astronomical telescopes.
基金financially supported by the Chinese National Basic Research 973 Program(2012CB416604,2007CB411307)the National Natural Science Foundation of China(41230207,41390441,41190075)the One Hundred Talent Program B of the Chinese Academy of Sciences
文摘How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central Asian Orogenic Belt(CAOB) in Northwest China,offer a special natural laboratory to resolve this puzzle.In the Chinese Altay,the Erqis unit consists of ophiolitic melanges and coherent assemblages,forming a Paleozoic accretionary complex.At least two ophiolitic melanges(Armantai,and Kelameili) in East Junggar,characterized by imbricated ophiolitic melanges,Nb-enriched basalts,adakitic rocks and volcanic rocks,belong to a Devonian-Carboniferous intra-oceanic island arc with some Paleozoic ophiolites,superimposed by Permian arc volcanism.In the Tianshan,ophiolitic melanges like Kanggurtag,North Tianshan,and South Tianshan occur as part of some Paleozoic accretionary complexes related to amalgamation of arc terranes.In the Beishan there are also several ophiolitic melanges,including the Hongshishan,Xingxingxia-Shibangjing,Hongliuhe-Xichangjing,and Liuyuan ophiolitic units.Most ophiolitic melanges in the study area are characterized by ultramafic,mafic and other components,which are juxtaposed,or even emplaced as lenses and knockers in a matrix of some coherent units.The tectonic settings of various components are different,and some adjacent units in the same melange show contrasting different tectonic settings.The formation ages of these various components are in a wide spectrum,varying from Neoproterozoic to Permian.Therefore we cannot assume that these ophiolitic melanges always form in linear sutures as a result of the closure of specific oceans.Often the ophiolitic components formed either as the substrate of intra-oceanic arcs,or were accreted as lenses or knockers in subduction-accretion complexes.Using published age and paleogeographic constraints,we propose the presence of (1) a major early Paleozoic tectonic boundary that separates the Chinese Altay-East Junggar multiple subduction systems of the southern Siberian active margin from those of the northern Tarim;and (2) a major Permian suture zone that separates the Tianshan-Beishan from the northern active margin of the Tarim Craton.These new observations and interpretations have broad implications for the architecture and crustal growth of central Asia and other ancient orogens as well.
基金financially supported by 973 Program(Grant No. 2014CB440801)NSFC(Grant Nos.41230207 and 41302167)+1 种基金China Postdoctoral Council(Grant Nos.20100480452,2012T50135 and International Postdoctoral Exchange Fellowship)State Key Laboratory of Earthquake Dynamics(Grant No.LED2013B03)
文摘Tarim Precambrian bedrocks are well exposed in the Kuluketage and Aksu areas, where twenty four samples were taken to reveal the denudation history of the northern Tarim Craton. Apatite fission track dating and thermal history modeling suggest that the northern Tarim experienced multi-stage cooling events which were assumed to be associated with the distant effects of the Cimmerian orogeny and India-Eurasia collision in the past. But the first episode of exhumation in the northern Tarim, occurring in the mid-Permian to Triassic, is here suggested to be induced by docking of the Tarim Craton and final amalgamation of the Central Asian Orogenic Belt. The cooling event at ca. 170 Ma may be triggered by the Qiangtang-Eurasia collision. Widespread Cretaceous exhumation could be linked with docking of the Lhasa terrane in the late Jurassic. Cenozoic reheating and recooling likely occurred because of the northpropagating stress, however, this has not affected the northern Tarim much because the Tarim is characterized by rigid block-like motion.
基金financially supported by 973 Program(2014CB440801)NSFC (41230207 and 41302167)sponsored by State Key Laboratory of Earthquake Dynamics(LED2013B03)
文摘The Hongyanjing inter-arc basin, is located at the central part of Beishan Orogenic College (BOC), Gansu Province, northwest China. Thick sequences of Permian sediments were strongly folded, forming extremely spectacular superposed folds. To better understand the thermal history of Hongyanjing interarc basin and to potentially constrain the timing of deformation, apatite fission track thermochronology method was applied on two superposed folds in the Hongyanjing Basin. Samples from the basin, yield central AFT ages ranging from - 206 to 118 Ma. AFT peak ages were largely consistent between samples and can divided into three groups: 245, 204-170 and 112-131 Ma. Subsequent thermal history modeling of the samples from the Hongyanjing Basin can be summarized as follows: (1) thermal reheating by sedimentary burial at - 260 to -220 Ma; (2) major cooling from -220 to -180 Ma; (3) an episode of very slow subsequent cooling from -180 to 65 Ma (-80 ℃) to present-day outcrop temperatures. Sediments in the Hongyanjing Basin were folded forming F1 fold during the early to late Triassic (-240--220 Ma), by regional stress, and at the time that the adjacent Xingxingxia shear zone started to become active. It is further suggested that the F2 folding occurred at -225-219 Ma. The deformation age of F2 should he extended to 180 Ma based on our thermal history modeling for the Hongyanjing Basin, which show a rapid exhumation and cooling at the late Triassic to early Jurassic (-220-- 180 Ma). In our interpretations, the F1 folding is therefore thought to he related to the final closure of the Paleo-Asian Ocean, while the F2 folding occurred at - 225-180 Ma associated with a major pulse of orogenesis in the BOC.
文摘Background Ultrasound-guided continuous thoracic paravertebral block can provide pain-relieving and opioid-sparing effects in patients receiving open hepatectomy.We hypothesize that these effects may improve the quality of recovery(QoR)after open hepatectomy.Methods Seventy-six patients undergoing open hepatectomy were randomized to receive a continuous thoracic paravertebral block with ropivacaine(CTPVB group)or normal saline(control group).All patients received patient-controlled intravenous analgesia with morphine postoperatively for 48 hours.The primary outcome was the global Chinese 15-item Quality of Recovery score on postoperative day 7,which was statistically analyzed using Student’s t-test.Results Thirty-six patients in the CTPVB group and 37 in the control group completed the study.Compared to the control group,the CTPVB group had significantly increased global Chinese 15-item Quality of Recovery scores(133.14±12.97 vs.122.62±14.89,P=0.002)on postoperative day 7.Postoperative pain scores and cumulative morphine consumption were significantly lower for up to 8 and 48 hours(P<0.05;P=0.002),respectively,in the CTPVB group.Conclusion Perioperative CTPVB markably promotes patient’s QoR after open hepatectomy with a profound analgesic effect in the early postoperative period.
基金This work was supported financially by Edible mushroom resources exploitation and the key technology development in efficient processing,“National Key R&D Program of China”[Project No.2018YFD0400200]Liaoning Province,Shenyang Agricultural University,high-end talent introduction fund project[grant number SYAU20160003].
文摘This study evaluated the effects of worm infection on the volatile components,total phenolic compounds,and antioxidant capacities of Gomphidius rutilus.G.rutilus without worms(GW),G.rutilus infected by a small amount of worms(GS;infected area<50%),and G.rutilus infected by a large amount of worms(GL;infected area>50%)were investigated.The volatile components of G.rutilus were analyzed by simultaneous distillation–extraction(SDE)and headspace solid-phase microextraction(HS-SPME)using gas chromatography–mass spectrometry(GC–MS).A total of 17 and 19 types of volatile compounds were detected,including ketones,alcohols,benzene,alkenes,aldehydes,esters,acids,and alkanes.Alcohols comprised the most abundant compound in GL,GS,and GW.The relative content of 1-octen-3-ol was the highest in all mushrooms.The concentration of eight-carbon(C8)compounds relative to the total volatile compounds varied widely,ranging from 40%(GW)to 64.34%(GS)and 84.42%(GS)and to 91.59%(GL),respectively,among the three samples.The antioxidant capability and the total phenolic contents of G.rutilus were evaluated in this study.The highest total phenolic content(TPC)of 192.23 mg GAE/g was found in GL,which differed significantly(P<0.05)from the latter two samples,whereas the lowest value of 156.11 mg GAE/g was found in GW.ABTS radical cation scavenging activity,FRAP ferric reducing antioxidant capacity(FRAP)radical scavenging activity,and oxygen radical absorbance capacity(ORAC)were investigated to screen the antioxidant properties of extracts.The contents of total phenolic compounds and their antioxidant capacities in vitro showed significant correlations(P<0.01).Among the three types of samples,the phenolic compounds of GL exhibited the highest antioxidant capacity,showing the values of 0.089 mM TE/g for ABTS,0.949 mM Fe^2+E/g for FRAP,and 1.952 M TE/g for ORAC.However,regarding the total antioxidant capacity,GS exhibited the highest antioxidant capacity,showing the values of 0.002648 mM TE/g for ABTS,0.004437 mM Fe^2+E/g for FRAP,and 0.256μM TE/g for ORAC.In conclusion,HS-SPME was more suitable for the extraction of volatile aroma components from G.rutilus.GL had the most abundant aroma components.GL had the highest TPC and antioxidant capacity compared with those of GS and GW,whereas GS showed the opposite results.Interestingly,GS was found to have the highest total antioxidant capacity in vitro.Based on these measured indicators,worm infection had no negative effect on the quality of G.rutilus.Therefore,worm-infected G.rutilus can also be consumed by humans.
文摘An infrared (IR) imaging simulation framework based on the strap-down platform is proposed for midcourse ballistic targets. It overcomes the shortcoming of the existing algorithms, which cannot simulate IR imaging from the entire midcourse process. The proposed framework includes three steps, target characteristic modeling, motion modeling, and imaging modeling. In imaging modeling, the staring focal plane is taken into account due to its wide employment. In order to obtain IR images of high fidelity, especially that the fluctuation of the target signal-to-noise ratio (SNR) is reasonably similar to the actual one, this paper proposes an improved IR imaging simulation method. The proposed method considers two critical factors of the pixel plane, occupy-empty ratio and defect elements, which affect the imaging of targets markedly but are neglected in previous work. Finally, the IR image sequence of high fidelity is obtained. And the correlative parameters of simulation can be set according to the given scene. Thus the generated images can satisfy the needs of algorithms validation for tracking and recognition.
文摘OBJECTIVE Vertebral metastases are a common manifestation in patients with advanced cancer and treatment is often ineffective. This study was conducted to explore the efficacy of treating vertebral metastases by percutaneous vertebroplasty (PVP) combined with interventional chemotherapy. METHODS Seventy-five patients with vertebral metastases (42 men, 33 women; ages 31-76 years) were divided into 2 groups: 39 cases were treated by PVP combined with chemotherapy (VPCC group), and 36 cases were treated by PVP alone (VP group). All procedures were guided by computed tomography (CT) scanning. The results and complications were evaluated by a questionnaire regarding pain and routine follow-up. RESULTS The response rate was significantly higher in the VPCC group than in the VP group (93.0% vs 74.4%, P〈0.05); total response rates for the VPCC and VP groups were 25.6% and 10.3% respectively. A common complication related to VPCC was transient aggravating pain. CONCLUSION PVP may ameliorate pain, and consolidate the vertebrae of patients with vertebral metastases. Its short-term effect may be enhanced by adding drugs into the bone cement.
基金a grant from Department of Public Health of Heibei Province, No. 20100134
文摘The influence of mild hypothermia on neural cell apoptosis remains poorly understood. Therefore, the present study established rat models of diffuse axonal injury (DAI) at 33℃. Morris water maze results demonstrated significantly better learning and memory functions in DAI rats with hypothermia compared with DAI rats with normothermia. Expression of apoptotic protease activating factor-1 in the hippocampal CA1 region was significantly lower in the DAI hypothermia group compared with the DAI normothermia group. Expression of apoptotic protease activating factor-1 positively correlated with latency, but negatively correlated with platform location times and time of swimming in the quadrant area. Results suggested that post-traumatic mild hypothermia in a rat model of DAI could provide cerebral protection by attenuating expression of apoptotic protease activating factor-1.
基金Key Research and Development Program of Shaanxi(Program No.2019SF-023)Basic Research Program of Natural Science in Shaanxi Province(Program No.2020JM-381)for their financial support.
文摘:Colorectal cancer(CRC)is a heterogeneous cancer,and many risk factors for colorectal cancer have been established.For CRC metastasis,tumor cell migration,adhesion as well as invasion are important processes.Wiskott-Aldrich syndrome protein family member 3(WASF3)is necessary for metastasis of various types of cancers.However,its role in CRC progression has not been fully elucidated.This study examined the in vitro functional roles of WASF3 in the CRC and explored the underlying molecular mechanisms.We used siRNA-WASF3 to gene silence WASF3 in colon cancer cell(HCT116)in vitro.The effects of WASF3 silencing on HCT116 cell apoptosis,proliferation,migration,as well as invasion were assessed by flow cytometry,CCK-8,and transwell assays.ZNF471 protein expressions were detected by immunofluorescence staining and RT-PCR.Moreover,the effects of ZNF471 were studied on a series of in vitro antitumor-promoting assays using HCT116.WASF3 knockdown expression using small interfering RNA(siRNA)ameliorated CRC cell proliferation,anchorage-independent growth,invasion,and metastasis.Furthermore,we observed that WASF3 contributed to upregulating the metastasis signaling pathway through inhibiting the expression of ZNF471.Our study suggests that targeting WASF3 signaling might be a novel therapeutic strategy for treating CRC.
基金Project supported by the National Natural Science Foundation of China(Grant No.61474090)the Key Research and Development Program of Shaanxi Province of China(Grant No.2017ZDXM-GY-052)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.20109205456)the Innovation Fund of Xidian University。
文摘The steady-state and transient electron transport properties ofβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructures were investigated by Monte Carlo simulation with the classic three-valley model.In particular,the electronic band structures were acquired by first-principles calculations,which could provide precise parameters for calculating the transport properties of the two-dimensional electron gas(2DEG),and the quantization effect was considered in theΓvalley with the five lowest subbands.Wave functions and energy eigenvalues were obtained by iteration of the Schrödinger–Poisson equations to calculate the 2DEG scattering rates with five main scattering mechanisms considered.The simulated low-field electron mobilities agree well with the experimental results,thus confirming the effectiveness of our models.The results show that the room temperature electron mobility of theβ-(Al_(0.188)Ga_(0.812))_(2)O_(3)/Ga_(2)O_(3)heterostructure at 10 k V·cm^(-1)is approximately153.669 cm^(2)·V^(-1)·s^(-1),and polar optical phonon scattering would have a significant impact on the mobility properties at this time.The region of negative differential mobility,overshoot of the transient electron velocity and negative diffusion coefficients are also observed when the electric field increases to the corresponding threshold value or even exceeds it.This work offers significant parameters for theβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructure that may benefit the design of high-performanceβ-(Al_(x)Ga_(1-x))_(2)O_(3)/Ga_(2)O_(3)heterostructure-based devices.
文摘Ventricular tachycardia storm (VTS) is defined as a life-threatening syndrome of three or more separate episodes of ventricular tachycardia (VT) leading to implantable cardioverter defibrillator (ICD) therapy within 24 hours. Patients with VTS have poor outcomes and require immediate medical attention. ICD shocks have been shown to be associated with increased mortality in several studies. Optimal programming in minimization of ICD shocks may decrease mortality. Large controlled trials showed that long detection time and high heart rate detection threshold reduced ICD shock burden without an increase in syncope or death. As a fundamental therapy of ICD, anti- tachycardia pacing (ATP) can terminate most slow VT with a low risk of acceleration. For fast VT, burst pacing is more effective and less likely to result in acceleration than ramp pacing. One algorithm of optimal programming management during a VTS is presented in the review.