Autonomously self-propelled nanoswimmers represent the nextgeneration nano-devices for bio-and environmental technology.However,current nanoswimmers generate limited energy output and can only move in short distances ...Autonomously self-propelled nanoswimmers represent the nextgeneration nano-devices for bio-and environmental technology.However,current nanoswimmers generate limited energy output and can only move in short distances and duration,thus are struggling to be applied in practical challenges,such as living cell transportation.Here,we describe the construction of biodegradable metal-organic framework based nanobots with chemically driven buoyancy to achieve highly efficient,long-distance,directional vertical motion to“find-and-fetch”target cells.Nanobots surface-functionalized with antibodies against the cell surface marker carcinoembryonic antigen are exploited to impart the nanobots with specific cell targeting capacity to recognize and separate cancer cells.We demonstrate that the self-propelled motility of the nanobots can sufficiently transport the recognized cells autonomously,and the separated cells can be easily collected with a customized glass column,and finally regain their full metabolic potential after the separation.The utilization of nanobots with easy synthetic pathway shows considerable promise in cell recognition,separation,and enrichment.展开更多
Distributed transmit beamforming(DTB) is very efficient for extending the communication distance between a swarm of UAVs and the base,particularly when considering the constraints in weight and battery life for payloa...Distributed transmit beamforming(DTB) is very efficient for extending the communication distance between a swarm of UAVs and the base,particularly when considering the constraints in weight and battery life for payloads on UAVs.In this paper,we review major function modules and potential solutions in realizing DTB in UAV systems,such as timing and carrier synchronization,phase drift tracking and compensation,and beamforming vector generation and updating.We then focus on beamforming vector generation and updating,and introduce a concatenated training scheme,together with a recursive channel estimation and updating algorithm.We also propose three approaches for tracking the variation of channels and updating the vectors.The effectiveness of these approaches is validated by simulation results.展开更多
Random access is a well-known multiple access method for uncoordinated communication nodes.Existing work mainly focuses on optimizing iterative access protocols,assuming that packets are corrupted once they are collid...Random access is a well-known multiple access method for uncoordinated communication nodes.Existing work mainly focuses on optimizing iterative access protocols,assuming that packets are corrupted once they are collided,or that feedback is available and can be exploited.In practice,a packet may still be able to be recovered successfully even when collided with other packets.System design and performance analysis under such a situation,particularly when the details of collision are taken into consideration,are less known.In this paper,we provide a framework for analytically evaluating the actual detection performance in a random temporal multiple access system where nodes can only transmit.Explicit expressions are provided for collision probability and signal to interference and noise ratio(SINR)when different numbers of packets are collided.We then discuss and compare two receiver options for the AP,and provide detailed receiver design for the premium one.In particular,we propose a synchronization scheme which can largely reduce the preamble length.We also demonstrate that system performance could be a convex function of preamble length both analytically and via simulation,as well as the forward error correction(FEC)coding rate.展开更多
In this paper, the influence of s-semipermutable, c~#-normal, subnormally embedded and ss-quasinormal subgroups on the p-nilpotency of finite groups is investigated and some recent results are generalized.
Background: The purpose of this study was to evaluate the association among serum organochlorine pesticide residues, glutathione S-transferase M1 genetic polymorphism and female breast cancer. Methods: A 1:1 matched c...Background: The purpose of this study was to evaluate the association among serum organochlorine pesticide residues, glutathione S-transferase M1 genetic polymorphism and female breast cancer. Methods: A 1:1 matched case-control study of 140 newly diagnosed breast cancer patients and 140 non-cancer female patients who consulted the five largest hospitals in the Tangshan city from September 2006 to October 2007. Results: The result showed higher risk of breast cancer among subjects with higher levels of serum DDT and HCH residue, the OR was 3.18 (95%CI, 1.11 - 9.07) and 5.02 (95%CI, 1.64 - 16.56).The value of ORe associated with single environmental factor DDT high residues, and ORg associated with single GSTM1 deletion genotype were respectively 3.86 (1.20 - 12.47) and 1.34 (0.36 - 5.08). The OReg associated with combined action of two factors was 5.59 (1.63 - 18.90), and the value of interaction parameters (γ) equaled 1.24. The value of ORe associated with single environmental factor HCH higher residue and ORg associated with single GSTM1 deletion genotype were respectively 2.73 (0.84 - 8.87) and 1.48 (0.49 - 4.60). The value of OReg associated with combined action of two factors was 3.87 (1.18 - 12.68), and γ equaled 1.38. Conclusion: The results indicated that breast cancer occurrence was the combined result of environmental and genetic factors. The concurrent action of GSTM1 deletion genotype and DDT/HCH enhanced the risk of breast cancer.展开更多
基金supported by the Australian Research Council (ARC, DP210100422)the National Breast Cancer Foundation, Australia (IIRS-22-104)the financial support by the Australian Government Research Training Program Scholarship
文摘Autonomously self-propelled nanoswimmers represent the nextgeneration nano-devices for bio-and environmental technology.However,current nanoswimmers generate limited energy output and can only move in short distances and duration,thus are struggling to be applied in practical challenges,such as living cell transportation.Here,we describe the construction of biodegradable metal-organic framework based nanobots with chemically driven buoyancy to achieve highly efficient,long-distance,directional vertical motion to“find-and-fetch”target cells.Nanobots surface-functionalized with antibodies against the cell surface marker carcinoembryonic antigen are exploited to impart the nanobots with specific cell targeting capacity to recognize and separate cancer cells.We demonstrate that the self-propelled motility of the nanobots can sufficiently transport the recognized cells autonomously,and the separated cells can be easily collected with a customized glass column,and finally regain their full metabolic potential after the separation.The utilization of nanobots with easy synthetic pathway shows considerable promise in cell recognition,separation,and enrichment.
基金supported by National Natural Science Foundation of China(No.61271236)Major Projects of Natural Science Research of Jiangsu Provincial Universities(No.17KJA510004)Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX17_0763)
文摘Distributed transmit beamforming(DTB) is very efficient for extending the communication distance between a swarm of UAVs and the base,particularly when considering the constraints in weight and battery life for payloads on UAVs.In this paper,we review major function modules and potential solutions in realizing DTB in UAV systems,such as timing and carrier synchronization,phase drift tracking and compensation,and beamforming vector generation and updating.We then focus on beamforming vector generation and updating,and introduce a concatenated training scheme,together with a recursive channel estimation and updating algorithm.We also propose three approaches for tracking the variation of channels and updating the vectors.The effectiveness of these approaches is validated by simulation results.
基金supported by National Natural Science Foundation of China (No. 61271236)Major Projects of Natural Science Research of Jiangsu Provincial Universities (No. 17KJA510004)Postgraduate Research & Practice Innovation Program of Jiangsu Province (No. KYCX17_0763, No.KYCX18_0907)
文摘Random access is a well-known multiple access method for uncoordinated communication nodes.Existing work mainly focuses on optimizing iterative access protocols,assuming that packets are corrupted once they are collided,or that feedback is available and can be exploited.In practice,a packet may still be able to be recovered successfully even when collided with other packets.System design and performance analysis under such a situation,particularly when the details of collision are taken into consideration,are less known.In this paper,we provide a framework for analytically evaluating the actual detection performance in a random temporal multiple access system where nodes can only transmit.Explicit expressions are provided for collision probability and signal to interference and noise ratio(SINR)when different numbers of packets are collided.We then discuss and compare two receiver options for the AP,and provide detailed receiver design for the premium one.In particular,we propose a synchronization scheme which can largely reduce the preamble length.We also demonstrate that system performance could be a convex function of preamble length both analytically and via simulation,as well as the forward error correction(FEC)coding rate.
基金Supported by SRFPYED(2017ZDX041)and SRFPYED(2016ZDX151)
文摘In this paper, the influence of s-semipermutable, c~#-normal, subnormally embedded and ss-quasinormal subgroups on the p-nilpotency of finite groups is investigated and some recent results are generalized.
文摘Background: The purpose of this study was to evaluate the association among serum organochlorine pesticide residues, glutathione S-transferase M1 genetic polymorphism and female breast cancer. Methods: A 1:1 matched case-control study of 140 newly diagnosed breast cancer patients and 140 non-cancer female patients who consulted the five largest hospitals in the Tangshan city from September 2006 to October 2007. Results: The result showed higher risk of breast cancer among subjects with higher levels of serum DDT and HCH residue, the OR was 3.18 (95%CI, 1.11 - 9.07) and 5.02 (95%CI, 1.64 - 16.56).The value of ORe associated with single environmental factor DDT high residues, and ORg associated with single GSTM1 deletion genotype were respectively 3.86 (1.20 - 12.47) and 1.34 (0.36 - 5.08). The OReg associated with combined action of two factors was 5.59 (1.63 - 18.90), and the value of interaction parameters (γ) equaled 1.24. The value of ORe associated with single environmental factor HCH higher residue and ORg associated with single GSTM1 deletion genotype were respectively 2.73 (0.84 - 8.87) and 1.48 (0.49 - 4.60). The value of OReg associated with combined action of two factors was 3.87 (1.18 - 12.68), and γ equaled 1.38. Conclusion: The results indicated that breast cancer occurrence was the combined result of environmental and genetic factors. The concurrent action of GSTM1 deletion genotype and DDT/HCH enhanced the risk of breast cancer.
