We extend the exciton population equations of a two-level quantum dot system with weak excitation to the ones with strong excitations, in which, the phonon-induced intensity-dependent dephasing time and decay rate are...We extend the exciton population equations of a two-level quantum dot system with weak excitation to the ones with strong excitations, in which, the phonon-induced intensity-dependent dephasing time and decay rate are involved. The straightforward calculated populations from the modified population equations demonstrate the damping behavior of Rabi oscillation as the external field increasing. The effect of the intensity-dependent dephasing time and the intensity-dependent decay rate are also discussed.展开更多
目的复发鼻咽癌再程放疗困难重重,再程放疗后晚期放射损伤发生率高,且5年生存率低。本研究对比分析大分割与常规分割三维适形放疗治疗鼻咽复发鼻咽癌的放射损伤反应、生活质量影响及疗效。方法回顾性分析中国人民解放军联勤保障部队第...目的复发鼻咽癌再程放疗困难重重,再程放疗后晚期放射损伤发生率高,且5年生存率低。本研究对比分析大分割与常规分割三维适形放疗治疗鼻咽复发鼻咽癌的放射损伤反应、生活质量影响及疗效。方法回顾性分析中国人民解放军联勤保障部队第九二一医院肿瘤科2008-11-06-2012-10-25收治的复发鼻咽癌患者117例,按治疗情况分成鼻咽癌复发常规分割适形放疗组(对照组59例)和鼻咽癌复发大分割适形放疗组(研究组58例),对照组为常规分割,5次/周,2Gy/次,共30～35次,总量60～70Gy/6～7周。研究组为大分割,5次/周,3Gy/次,共17～20次,总量51～60Gy/4周,观察放射损伤反应、生活质量影响、近期疗效、远期疗效等。结果两组患者近期放射损伤反应如口干(χ~2=1.029,P=0.310)、颌面部皮肤反应(χ~2=1.239,P=0.266)、乏力(χ~2=0.210,P=0.646)发生率差异均无统计学意义。研究组口腔黏膜反应(46.6%)明显比对照组(25.4%)高,χ~2=5.674;P=0.017;两组患者远期放射损伤如口干(χ~2=0.364,P=0.546)、颌面部肌肉纤维化(χ~2=0.010,P=0.919)、放射性脑病(χ~2=1.143,P=0.285)发生率差异均无统计学意义。研究组耳聋(χ~2=4.414,P=0.043)、张口困难(χ~2=4.499,P=0.034)明显比对照组高;两组鼻咽癌患者生活质量评价(KPS评分、体质量变化)治疗前与治疗结束时、治疗结束时与治疗后3个月对比,均P>0.05;3个月后局部控制率(tumor control probability,TCP)对照组为54.2%(32/59),研究组为69.0%(40/58),差异无统计学意义,χ~2=2.681,P=0.102;6个月后对照组TCP为62.7%(37/59),研究组为79.3%(46/58),差异有统计学意义,χ~2=3.909,P=0.048;9个月后对照组TCP为67.8%(40/59),研究组为84.5%(49/58),差异有统计学意义,χ~2=4.473,P=0.034;12个月后对照组TCP为69.5%(41/59),研究组为87.9%(51/58),差异有统计学意义,χ~2=5.919,P=0.015。对照组1年生存率(overallsurvival,OS)为94.9%(56/59),研究组为96.6%(56/58),差异无统计学意义,χ~2=1.191,P=0.662;2年对照组OS为71.2%(42/59),研究组为81.0%(47/58),差异无统计学意义,χ~2=1.558,P=0.212;3年对照组OS为50.8%(30/59),研究组为69.0%(40/58),差异有统计学意义,χ~2=3.995,P=0.046;4年对照组OS为39.0%(23/59),研究组为58.6%(34/58),差异有统计学意义,χ~2=4.515,P=0.034;5年对照组OS为32.2%(19/59),研究组为51.7%(30/58),差异有统计学意义,χ~2=4.579,P=0.032。结论复发鼻咽癌治疗中,大分割三维适形放疗比常规分割放疗疗程有明显缩短,从而降低了部分放射损伤反应,对生活质量影响较小,能明显提高肿瘤的TCP,近期疗效和远期疗效较好。展开更多
基金The project supported by National Natural Science Foundation of China under Grant Nos. 10534030 and 10474075
文摘We extend the exciton population equations of a two-level quantum dot system with weak excitation to the ones with strong excitations, in which, the phonon-induced intensity-dependent dephasing time and decay rate are involved. The straightforward calculated populations from the modified population equations demonstrate the damping behavior of Rabi oscillation as the external field increasing. The effect of the intensity-dependent dephasing time and the intensity-dependent decay rate are also discussed.
文摘目的复发鼻咽癌再程放疗困难重重,再程放疗后晚期放射损伤发生率高,且5年生存率低。本研究对比分析大分割与常规分割三维适形放疗治疗鼻咽复发鼻咽癌的放射损伤反应、生活质量影响及疗效。方法回顾性分析中国人民解放军联勤保障部队第九二一医院肿瘤科2008-11-06-2012-10-25收治的复发鼻咽癌患者117例,按治疗情况分成鼻咽癌复发常规分割适形放疗组(对照组59例)和鼻咽癌复发大分割适形放疗组(研究组58例),对照组为常规分割,5次/周,2Gy/次,共30～35次,总量60～70Gy/6～7周。研究组为大分割,5次/周,3Gy/次,共17～20次,总量51～60Gy/4周,观察放射损伤反应、生活质量影响、近期疗效、远期疗效等。结果两组患者近期放射损伤反应如口干(χ~2=1.029,P=0.310)、颌面部皮肤反应(χ~2=1.239,P=0.266)、乏力(χ~2=0.210,P=0.646)发生率差异均无统计学意义。研究组口腔黏膜反应(46.6%)明显比对照组(25.4%)高,χ~2=5.674;P=0.017;两组患者远期放射损伤如口干(χ~2=0.364,P=0.546)、颌面部肌肉纤维化(χ~2=0.010,P=0.919)、放射性脑病(χ~2=1.143,P=0.285)发生率差异均无统计学意义。研究组耳聋(χ~2=4.414,P=0.043)、张口困难(χ~2=4.499,P=0.034)明显比对照组高;两组鼻咽癌患者生活质量评价(KPS评分、体质量变化)治疗前与治疗结束时、治疗结束时与治疗后3个月对比,均P>0.05;3个月后局部控制率(tumor control probability,TCP)对照组为54.2%(32/59),研究组为69.0%(40/58),差异无统计学意义,χ~2=2.681,P=0.102;6个月后对照组TCP为62.7%(37/59),研究组为79.3%(46/58),差异有统计学意义,χ~2=3.909,P=0.048;9个月后对照组TCP为67.8%(40/59),研究组为84.5%(49/58),差异有统计学意义,χ~2=4.473,P=0.034;12个月后对照组TCP为69.5%(41/59),研究组为87.9%(51/58),差异有统计学意义,χ~2=5.919,P=0.015。对照组1年生存率(overallsurvival,OS)为94.9%(56/59),研究组为96.6%(56/58),差异无统计学意义,χ~2=1.191,P=0.662;2年对照组OS为71.2%(42/59),研究组为81.0%(47/58),差异无统计学意义,χ~2=1.558,P=0.212;3年对照组OS为50.8%(30/59),研究组为69.0%(40/58),差异有统计学意义,χ~2=3.995,P=0.046;4年对照组OS为39.0%(23/59),研究组为58.6%(34/58),差异有统计学意义,χ~2=4.515,P=0.034;5年对照组OS为32.2%(19/59),研究组为51.7%(30/58),差异有统计学意义,χ~2=4.579,P=0.032。结论复发鼻咽癌治疗中,大分割三维适形放疗比常规分割放疗疗程有明显缩短,从而降低了部分放射损伤反应,对生活质量影响较小,能明显提高肿瘤的TCP,近期疗效和远期疗效较好。
