临床医学专业课程混合式教学效果探析

在面临教育教学改革的大环境下,如何探讨和评价临床医学专业课程混合式教学运用的效果,以西北民族大学2017级临床医学本科专业114名学生为研究对象,采用Willianmson量表进行问卷调查,运用克隆巴赫信度、方差分析等统计学方法,对西北民族大学附属医院的临床案例分析、模拟教学、线上线下混合式教学等的教学效果进行评价。数据分析结果显示:2017级临床医学专业学生对课程混合式教学模式的认可度具有一致性和普遍性,男性和女性认可度稍有差异。因此,混合式教学模式能够为医学生带来更多体验,激发了学生的学习热情,有利于医学生的培养。

以临床为导向的外科手术学实验教学设计

国家本科医学教育标准颁布后,对医学教育质量提出了更加严格的要求.要改变学生进入临床后动手能力差、临床思维能力缺乏的现状,就需要以临床为导向,紧抓外科手术学教学的核心和关键,改变教学思路,完善课程内容,丰富教学方法和手段,建立科学合理的考核评价体系,使得外科手术学实验教学更好地与临床实际接轨,才能培养出具有良好医学综合素质、符合现代医学发展需求的合格医学生.

Correspondence Between Oscillations and Emitted Photon Closed-Orbits in Spontaneous Emission Rate of an Atom Near a Dielectric Slab

We study the oscillations in the spontaneous emission rate of an atom near a dielectric slab. The emission rate is calculated as a function of system size using quantum electrodynamics. It exhibits multi-periodic oscillations. Four frequencies of the oscillations are extracted by Fourier transforms. They agree with actions of photon closed-orbits going away and returning to the atom. These oscillations are explained as manifestations of quantum interference effects between the emitted photon wave near the atom and the returning photon waves travelling along various closed-orbits.

Interface Effects on the Magneto-Optical Kerr Effect and Optical Properties in Co/Ni Multilayer

The influence of interfaces on the magneto-optical Kerr effect in the Co/Ni multilayer has been investigated.It was found that the magnetic-optical Kerr rotation varies with the numbers of interfaces(x)in Co/Ni multilayer,which indicated that the interface states play an important role in the Kerr effect.Moreover,ellipticity and optical constants n and k are also found to vary with x.Some possible mechanisms have been discussed.

Critical Point of Ising Films with Different Growth Directions

The critical temperature Tc of a spin-1/2 Ising film of cubic structures is calculated by the variational cumulant expansion method for three directions of growth.The results from different growth directions are analysed and compared with each other.In the present model,the Tc values depend largely on the number of nearest neighbors in a monolayer for films with the same number of monolayers but grown in different directions.For sc,bcc and fee structures,the highest Tc is found along the(100),(110),and(111)direction,respectively.

基于网络药理学与分子对接探讨黄芪-丹参治疗肝纤维化的作用机制

目的通过网络药理学与分子对接研究黄芪-丹参治疗肝纤维化作用机制。方法利用TCMSP数据库平台对黄芪、丹参有效成分及其相关作用靶点进行筛选;利用GeneCards和OMIM数据库平台对肝纤维化作用靶点进行筛选。利用Cytoscape软件构建“药物-成分-疾病-靶点”网络图,运用String和David数据库对靶点进行PPI网络、GO生物过程与KEGG通路分析。通过AutoDock Vina对成分和靶点进行分子对接。结果黄芪-丹参中共获得有效成分76个,与肝纤维化对应的靶点64个;GO生物过程102条,信号通路155条,主要涉及的信号通路有糖尿病并发症中的AGE-RAGE信号通路、IL-17信号通路、TNF信号通路、缺氧诱导因子1(HIF-1)信号通路等。分子对接显示黄芪、丹参中槲皮素、木犀草素、山柰酚和丹参酮ⅡA等与核心靶点AKT1、TP53、VEGFA、TNF、IL-6均具有较好的亲和力。结论黄芪-丹参治疗肝纤维化的作用机制具有“多成分、多靶点、多信号通路”的特点,为今后的实验研究提供了参考依据。