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2020—2022年某医院主要细菌耐药情况分析
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作者 朱爱兰 张书强 +1 位作者 吴林岚 魏建威 《中国卫生标准管理》 2024年第3期120-127,共8页
目的通过分析福建中医药大学附属第二人民医院2020年1月—2022年12月常见细菌的耐药性,了解医院的细菌耐药情况,为临床提供合理使用抗菌药物的参考依据。方法通过回顾性分析方法对2020年1月—2022年12月福建中医药大学附属第二人民医院... 目的通过分析福建中医药大学附属第二人民医院2020年1月—2022年12月常见细菌的耐药性,了解医院的细菌耐药情况,为临床提供合理使用抗菌药物的参考依据。方法通过回顾性分析方法对2020年1月—2022年12月福建中医药大学附属第二人民医院患者标本分离的病原菌株进行统计,从病原菌标本分布、病原菌种类及耐药等方面进行分析。结果2020—2022年分离的菌株共计12009株,呼吸道标本(包括痰、肺泡灌洗液)最多。前5位为大肠埃希菌2139株(17.81%)、肺炎克雷伯菌1342株(11.17%)、铜绿假单胞菌1094株(9.11%)、金黄色葡萄球菌为主793株(6.60%)、鲍曼不动杆菌541株(4.50%)。耐碳青霉烯类肺炎克雷伯菌(Carbapenemresistant K.pneumoniae,CR-KP)和耐碳青霉烯类铜绿假单胞菌(Carbapenemresistant Pseudomonas aeruginosa,CR-PA)2022年比2020年明显升高,差异有统计学意义(P<0.01)。其余3种耐甲氧西林金黄色葡萄球菌(Methicillin-resistant S.aureus,MRSA)、耐碳青霉烯类大肠埃希菌(Carbapenemresistant Escherichia coli,CR-EC)、耐碳青霉烯类鲍曼不动杆菌(Carbapenemresistant Acinetobacter baumannii,CRAB)3年间检出率差异无统计学意义(P>0.05)。鲍曼不动杆菌对大多数常用抗菌药物耐药率>50%。结论福建中医药大学附属第二人民医院主要以革兰阴性杆菌为主,鲍曼不动杆菌对大多数常用抗菌药物耐药率>50%,CR-KP(耐碳青霉烯类肺炎克雷伯菌)和CR-PA(耐碳青霉烯类铜绿假单胞菌)的耐药率呈增高趋势,建议临床密切关注病原菌耐药情况的变化,减少多重耐药菌的产生。 展开更多
关键词 细菌耐药 抗菌药物 耐碳青霉烯类肺炎克雷伯菌 耐碳青霉烯类铜绿假单胞菌 耐药率 多重耐药
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基于自动检测方法的福建地区断裂带地震活动性研究
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作者 刘芳 孙冬军 +3 位作者 周一剑 朱艾斓 魏薇 朴健 《地震学报》 CSCD 北大核心 2023年第3期538-549,共12页
利用福建地震台网88个地震台站于2015年记录的10个月的连续波形数据,基于台网约束下的长短窗特征触发式震相检测的模板事件识别方法和匹配滤波自动检测方法,识别出模板事件919个,匹配滤波后重新识别和定位了共计2243个地震事件,其中ML1.... 利用福建地震台网88个地震台站于2015年记录的10个月的连续波形数据,基于台网约束下的长短窗特征触发式震相检测的模板事件识别方法和匹配滤波自动检测方法,识别出模板事件919个,匹配滤波后重新识别和定位了共计2243个地震事件,其中ML1.0以上地震1991次,主要集中在ML1.0—1.5之间,这极大扩充了该震级范围内的福建地震台网目录。重新定位的地震震源深度分布在0—20 km之间,多数发生在10 km内的上地壳。沿长乐—诏安断裂带和永安—晋江断裂带,地震分布集中且表现出明显的分段活动性。在长乐—诏安断裂带上检测到较福建台网目录更多的地震,且地震活动性表现为西南段较强、东北段较弱,沿断裂带的震源深度分布由南向北逐渐变浅,与莫霍面深度的变化相一致;在与之共轭的永安—晋江断裂带上则北西段地震活动更为集中,而东南段地震活动稍显分散。重新识别与精定位后的地震与福建地区地壳水平形变南强北弱、东强西弱的特点相一致。 展开更多
关键词 自动地震检测方法 长乐—诏安断裂带 永安—晋江断裂带 地震活动性
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思政融入实验诊断学“临床常见病原体检测”单元教学中的探索
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作者 朱爱兰 魏建威 +2 位作者 郑登滋 徐丛荣 杨梅玉 《中国继续医学教育》 2023年第21期11-14,共4页
课程思政建设是专业课程教学改革的根本任务。课程思政是在讲授专业课程知识的基础上,融入与专业课程知识相关的思想政治教育元素,对高校大学生进行传授专业知识的同时进行思想政治教育。文章结合实验诊断学中“临床常见病原体检测”单... 课程思政建设是专业课程教学改革的根本任务。课程思政是在讲授专业课程知识的基础上,融入与专业课程知识相关的思想政治教育元素,对高校大学生进行传授专业知识的同时进行思想政治教育。文章结合实验诊断学中“临床常见病原体检测”单元课程专业知识内容,通过在教学过程中融入巴斯德发现微生物、弗莱明发现青霉素、噬菌体抗菌成传奇、临床背后的“幕后英雄”-检验人员、黄祯祥创新病毒的体外培养技术、国际共产主义战士——白求恩等典型课程思政教学案例,进一步挖掘案例中研究者的科学素养、医者仁心风范及爱国情怀,激发学生的使命感和责任感,达到“立德树人”的目标。 展开更多
关键词 课程思政 课程教学改革 实验诊断学 微生物 青霉素 思政教学案例
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Seismotectonics of the 2008 and 2009 Qaidam Earthquakes and its Implication for Regional Tectonics 被引量:5
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作者 CHEN Guihua XU Xiwei +4 位作者 zhu ailan ZHANG Xiaoqing YUAN Renmao Yann KLINGER Jean-Mathieu NOCQUET 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2013年第2期618-628,共11页
Three magnitude 〉6 earthquakes struck Qaidam, Qinghai province, China, in November 10th 2008, August 28th and 31st 2009 respectively. The Zongwulongshan fault has often been designated as the active seismogenic struc... Three magnitude 〉6 earthquakes struck Qaidam, Qinghai province, China, in November 10th 2008, August 28th and 31st 2009 respectively. The Zongwulongshan fault has often been designated as the active seismogenic structure, although it is at odd with the data. Our continuous GPS station (CGPS), the Xiao Qaidam station, located in the north of the Qaidam basin, is less than 30 km to the southwest of the 2008 earthquake. This CGPS station recorded the near field co-seismic deformation. Here we analyzed the co-seismic dislocation based on the GPS time series and the rupture processes from focal mechanism for the three earthquakes. The afiershocks were relocated to constrain the spatial characteristics of the 2008 and 2009 Qaidam earthquakes. Field geological and geomorphological investigation and interpretation of satellite images show that the Xitieshan fault and Zongwulongshan fault were activated as left lateral thrust during the late Quaternary. Evidence of folding can also be identified. Integrated analyses based on our data and the regional tectonic environment show that the Xitieshan fault is the fault responsible for the 2008 Qaidam earthquake, which is a low dip angle thrust with left lateral strike slip. The Zongwulongshan fault is the seismogenic fault of the 2009 earthquakes, which is a south dipping back thrust of the northern marginal thrust system of the Qaidam basin. Folding takes a significant part of the deformation in the northern marginal thrust system of the Qaidam basin, dominating the contemporary structure style of the northern margin of the Qaidam basin and Qilianshan tectonic system. In this region, this fault and fold system dominates the earthquake activities with frequent small magnitude earthquakes. 展开更多
关键词 Qaidam earthquakes SEISMOTECTONICS Xitieshan fault Zongwulongshan fault structure style
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Basic Characteristics of Active Structures in Western Sichuan and Its Vicinity and Strong Earthquake Recurrence Model
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作者 Xu Xiwei Zhang Peizhen +3 位作者 Wen Xueze Qin Zunli Chen Guihua zhu ailan 《Earthquake Research in China》 2006年第1期75-89,共15页
Western Sichuan and its vicinity are located in the juncture of three big active blocks, namely, the Chuandian (Sichuan and Yunnan), the Bayan Har and the South China blocks, on the eastern margin of the Qinghai-Xizan... Western Sichuan and its vicinity are located in the juncture of three big active blocks, namely, the Chuandian (Sichuan and Yunnan), the Bayan Har and the South China blocks, on the eastern margin of the Qinghai-Xizang(Tibet) Plateau. Many groups of active faults that are capable of generating earthquakes are developed there. Because there exist lateral secondary active faults, the Chuandian block can be further divided into the central Yunnan and northwestern Sichuan sub_blocks; while the Longmenshan sub_block can be divided on the east end of the Bayan Har block. Joint exploration of deep crustal structure shows that there exist low-velocity and high-conductivity layers in the crust of the Chuandian and Bayan Har blocks, which are one of the important factors that make the upper crust prone to earthquake. The results of geological study and modern GPS observation show that blocks of different orders all have SE-or SSE-trending sliding, clockwise rotation and upwelling movement; but there are some differences in amplitude. This paper has also given the geological or GPS slip rates of main active fault zones and discussed the main scientific problems still existing now. 展开更多
关键词 四川 活动性 地震 活动板块 循环模型
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Discussion of rupture mechanisms on the seismogenic fault of the 2008 M_s8.0 Wenchuan earthquake 被引量:19
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作者 DENG QiDong CHEN GuiHua zhu ailan 《Science China Earth Sciences》 SCIE EI CAS 2011年第9期1360-1377,共18页
The May 12, 2008, Ms8.0 Wenchuan earthquake was the outcome of a recent movement of an active intra-continental thrust fault zone. The seismogenic fault of this earthquake underwent oblique-slip faulting along the cen... The May 12, 2008, Ms8.0 Wenchuan earthquake was the outcome of a recent movement of an active intra-continental thrust fault zone. The seismogenic fault of this earthquake underwent oblique-slip faulting along the central fault and pure thrust faulting along the range-front fault of the Longmenshan fault zone. The former had a steep dip and large vertical displacement, and the latter had a gentle dip and little vertical displacement. The fault zone consisted of compressive double fault ramps rup turing with right-lateral strike-slip components resulting from strain partitioning of a deep oblique slip fault in the brittle zone of the upper crust. The kinematic pattern and rupture mechanisms are complex for the seismogenic fault, as indicated by the geometric pattern of its surface ruptures, the coseismic displacement distribution and focal mechanisms of the main shock and aftershocks. As a tear fault, the NW-trending, left-lateral, strike-slip Xiaoyudong fault zone has accommodated NE-trending displacements with different shortening amounts. However, because of intense compression on the southwestern segment of the seismogenic fault, the left-lateral, strike-slip Xiaoyudong fault also carries a clear compression component. Normal faulting with a strike-slip component controls the formation of a fault-trough along the central fault, which is characterized by thrusting with a strike-slip component and strike-slip with thrusting. The fault-troughs are the product of the interaction of slip and grav ity on the seismogenic fault under specific geological and geomorphic conditions. Gravitational force exaggerated the vertical component of fault displacement, which by no means represents the actual maximum vertical displacement of the seismogenic fault. 展开更多
关键词 发震断层 破裂机制 地震 汶川 龙门山断裂带 走滑断裂带 垂直位移 垂直分量
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