In this paper, toxicity and safety of high-dose irradiated chicken-breast meat were evaluated. For assays of acute toxicity, genetic toxicity, and sub-chronic toxicity, ames test, mice bone marrow erythrocyte micronuc...In this paper, toxicity and safety of high-dose irradiated chicken-breast meat were evaluated. For assays of acute toxicity, genetic toxicity, and sub-chronic toxicity, ames test, mice bone marrow erythrocyte micronucleus, and mice sperm abnormality were performed. The results showed that, in the acute oral toxicity tests, median lethal dose （more than 10 000 mg kg-~） in male and female ICR mice showed no toxicological signs. For subacute 30-d oral toxicology of irradiated chicken-breast meat with dose of 10, 15 and 25 kGy in both male and female SD rats, no noticeable toxicological effects were observed. It is concluded that chicken-breast meat with high-dose irradiation has no acute toxicity and no genotoxicity, nor harmful effects on the animal body at the tested dosage range. Therefore, high-dose irradiated chicken-breast meat is safe for pet consumption.展开更多
[ Object] The research is aimed to provide scientific basis for irradiated pet food＇s standardized production, supervision and commercial- ized application. E Method] Take broiler breast meat with high-dose irradiati...[ Object] The research is aimed to provide scientific basis for irradiated pet food＇s standardized production, supervision and commercial- ized application. E Method] Take broiler breast meat with high-dose irradiation as testing material, then evaluate its safety after 30 days feeding test of rats [ Result] Compared with control group （Pet food＇s irradiation dose is 0 kGy）, the general situation, weight, food-intake, food utilization rate, hematological examinations, bio-chemical analysis of blood, viscera weight, ratio of viscera and body weight, histopathological examinations, physi- ological feature, life＇s basic characteristics （including height, tail length, body temperature, heart rate and blood pressure ） and other indexes of rats, which were fed respectively with 10, 15, 25 kGy irradiation dose pet food for 30 days, were not found abnormal. [ Conclusion] Pet food with 10, 15, 25kGy irradiation dose is safe.展开更多
基金supported by the Special Fund for Agro-Scientific Research in the Public Interest, China(201103007)
文摘In this paper, toxicity and safety of high-dose irradiated chicken-breast meat were evaluated. For assays of acute toxicity, genetic toxicity, and sub-chronic toxicity, ames test, mice bone marrow erythrocyte micronucleus, and mice sperm abnormality were performed. The results showed that, in the acute oral toxicity tests, median lethal dose （more than 10 000 mg kg-~） in male and female ICR mice showed no toxicological signs. For subacute 30-d oral toxicology of irradiated chicken-breast meat with dose of 10, 15 and 25 kGy in both male and female SD rats, no noticeable toxicological effects were observed. It is concluded that chicken-breast meat with high-dose irradiation has no acute toxicity and no genotoxicity, nor harmful effects on the animal body at the tested dosage range. Therefore, high-dose irradiated chicken-breast meat is safe for pet consumption.
基金supported by" Special Fund for Agro-scientific Research in the Public Interest (201103007) "Jiangsu Agricultural Science Independent Innovation Capital[Serial Number:cx(10)449]
文摘[ Object] The research is aimed to provide scientific basis for irradiated pet food＇s standardized production, supervision and commercial- ized application. E Method] Take broiler breast meat with high-dose irradiation as testing material, then evaluate its safety after 30 days feeding test of rats [ Result] Compared with control group （Pet food＇s irradiation dose is 0 kGy）, the general situation, weight, food-intake, food utilization rate, hematological examinations, bio-chemical analysis of blood, viscera weight, ratio of viscera and body weight, histopathological examinations, physi- ological feature, life＇s basic characteristics （including height, tail length, body temperature, heart rate and blood pressure ） and other indexes of rats, which were fed respectively with 10, 15, 25 kGy irradiation dose pet food for 30 days, were not found abnormal. [ Conclusion] Pet food with 10, 15, 25kGy irradiation dose is safe.
