Taking Zhaoyu Historical City in Qixian County as an example,this paper explores the production process of tourism space in Zhaoyu Historical City in the context of consumption,based on Lefebvre's triadic dialecti...Taking Zhaoyu Historical City in Qixian County as an example,this paper explores the production process of tourism space in Zhaoyu Historical City in the context of consumption,based on Lefebvre's triadic dialectic theory.The study reveals that,driven by the development of tourism,subjects such as the government and planners possess absolute dominance over spatial representations,while residents demonstrate receptive and adaptive action strategies and social relations are reproduced,presenting a harmonious state.Further exploring the tourism community in the environmental performance of the subject of action,social relations,consumption demand,daily life practice,cultural capital,etc.,the daily life practice of the tourism community has transcended the original logic of tourism spatial production and has a certain extension.The mechanism analysis in this paper can help guide the healthy development of tourism space in the neighboring historical cities or communities and achieve the dual purpose of promoting the economic development of the community and heritage protection.展开更多
目的探讨5,10-亚甲基四氢叶酸还原酶(MTHFR)基因rs1801133位点多态性与脑卒中的相关性。方法共纳入华北理工大学附属医院脑卒中患者194例(病例组),再根据脑卒中类型分为缺血性脑卒中(IS)组和出血性脑卒中(ICH)组,无脑卒中相关病史的体检...目的探讨5,10-亚甲基四氢叶酸还原酶(MTHFR)基因rs1801133位点多态性与脑卒中的相关性。方法共纳入华北理工大学附属医院脑卒中患者194例(病例组),再根据脑卒中类型分为缺血性脑卒中(IS)组和出血性脑卒中(ICH)组,无脑卒中相关病史的体检者221例为对照组。收集一般资料和多项检验结果,提取空腹外周血中DNA,利用实时荧光PCR技术定性定量检测MTHFR基因rs1801133位点多态性。通过χ^(2)检验评估CC、CT和TT 3种基因型和C、T等位基因的差异。通过多因素二元Logistic回归分析包括CT、TT两种基因型在内的共12种因素与脑卒中的关系。结果在MTHFR基因rs1801133位点上相比较:IS组与ICH组基因型和等位基因频数无显著差异(P>0.05);但是病例组及IS、ICH组分别与对照组相比,基因型和等位基因频率差异有统计学意义(P<0.05)。在5种基因模型(等位基因模型:T vs C;显性模型:CT+TT vs CC;隐性模型:TT vs CC+CT;共显性杂合子模型:CT vs CC,共显性纯合子模型:TT vs CC)的分析结果中,均提示T等位基因携带者(CT/TT)较CC基因型发生脑卒中的风险增加(OR>1,P<0.05)。多因素二元Logistic回归分析表明:TT型、饮酒、高尿酸血症、吸烟、体质量指数、年龄为脑卒中的危险因素(P<0.05)。结论MTHFR基因rs1801133位点多态性与脑卒中的发生密切相关,T等位基因携带者发生脑卒中的风险较高,可作为该地区脑卒中发生风险的预测指标。展开更多
文摘Taking Zhaoyu Historical City in Qixian County as an example,this paper explores the production process of tourism space in Zhaoyu Historical City in the context of consumption,based on Lefebvre's triadic dialectic theory.The study reveals that,driven by the development of tourism,subjects such as the government and planners possess absolute dominance over spatial representations,while residents demonstrate receptive and adaptive action strategies and social relations are reproduced,presenting a harmonious state.Further exploring the tourism community in the environmental performance of the subject of action,social relations,consumption demand,daily life practice,cultural capital,etc.,the daily life practice of the tourism community has transcended the original logic of tourism spatial production and has a certain extension.The mechanism analysis in this paper can help guide the healthy development of tourism space in the neighboring historical cities or communities and achieve the dual purpose of promoting the economic development of the community and heritage protection.
文摘目的探讨5,10-亚甲基四氢叶酸还原酶(MTHFR)基因rs1801133位点多态性与脑卒中的相关性。方法共纳入华北理工大学附属医院脑卒中患者194例(病例组),再根据脑卒中类型分为缺血性脑卒中(IS)组和出血性脑卒中(ICH)组,无脑卒中相关病史的体检者221例为对照组。收集一般资料和多项检验结果,提取空腹外周血中DNA,利用实时荧光PCR技术定性定量检测MTHFR基因rs1801133位点多态性。通过χ^(2)检验评估CC、CT和TT 3种基因型和C、T等位基因的差异。通过多因素二元Logistic回归分析包括CT、TT两种基因型在内的共12种因素与脑卒中的关系。结果在MTHFR基因rs1801133位点上相比较:IS组与ICH组基因型和等位基因频数无显著差异(P>0.05);但是病例组及IS、ICH组分别与对照组相比,基因型和等位基因频率差异有统计学意义(P<0.05)。在5种基因模型(等位基因模型:T vs C;显性模型:CT+TT vs CC;隐性模型:TT vs CC+CT;共显性杂合子模型:CT vs CC,共显性纯合子模型:TT vs CC)的分析结果中,均提示T等位基因携带者(CT/TT)较CC基因型发生脑卒中的风险增加(OR>1,P<0.05)。多因素二元Logistic回归分析表明:TT型、饮酒、高尿酸血症、吸烟、体质量指数、年龄为脑卒中的危险因素(P<0.05)。结论MTHFR基因rs1801133位点多态性与脑卒中的发生密切相关,T等位基因携带者发生脑卒中的风险较高,可作为该地区脑卒中发生风险的预测指标。
