Objective To explore factors influencing the quality of life of people living with HIV/AIDS （PLHA） and receiving antiretroviral therapy （ART） in rural China. Methods In-depth interviews with 20 PLHA recruited from...Objective To explore factors influencing the quality of life of people living with HIV/AIDS （PLHA） and receiving antiretroviral therapy （ART） in rural China. Methods In-depth interviews with 20 PLHA recruited from the USAID-funded Longitudinal cohort of eligible PLHA receiving treatment were conducted in March 1999. Participants were Enhanced Evaluation of ART Project, which tracks a at five collaborating treatment centers in Guangxi Autonomous Region, China. An interview guide （semi-structured with open-ended questions） was developed to provide a qualitative examination of the quality of life of PLHA. Results Participants identified that ART affects physical health, including the experience of pain, side effects, and opportunistic infections. ART imposes lifestyle constraints such as reduced mobility due to drug procurement, and social restrictions due to the daily drug regimen. Participants discussed the psychological burden of taking drugs, and the fear of accidental transmission to others, or having their disease status known by others, as well as optimistic feelings about their future due to ART. ART poses a significant drain on individual＇s economic resources due to related medical costs, and inability to seek seasonal migrant labor due to reduced mobility. Conclusion While China＇s national free ART program improved the physical health of those surveyed, their social and economic needs were left unaddressed. To improve life outcomes for PLHA, and by extension, the wider Chinese population, quality of life measures should be included when evaluating the success of the ART program.展开更多
Combination antiretroviral therapy(ART)reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication,enhancing immune recovery,and preventing the onset of opportu...Combination antiretroviral therapy(ART)reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication,enhancing immune recovery,and preventing the onset of opportunistic infections[1].In China,ART has rapidly been scaled up since the beginning of the National Free Antiretroviral Treatment Program(NFATP)in 2003[2].By the end of 2016,489,411 individuals diagnosed with HIV were receiving free antiretroviral treatment in China.China is firmly committed to reducing overall AIDS-related mortality and HIV incidence within the country.However,similar to other low-and middle-income countries,the NFATP is challenged by high mortality and attrition shortly after patients initiate ART[3].展开更多
基金supported by USAID under the TASCIII TASC Order 2-Technical Support for HIV/AIDS Prevention,Care and Treatment-RDMA,Contract Number:GHS-I-00-07-0007-00
文摘Objective To explore factors influencing the quality of life of people living with HIV/AIDS （PLHA） and receiving antiretroviral therapy （ART） in rural China. Methods In-depth interviews with 20 PLHA recruited from the USAID-funded Longitudinal cohort of eligible PLHA receiving treatment were conducted in March 1999. Participants were Enhanced Evaluation of ART Project, which tracks a at five collaborating treatment centers in Guangxi Autonomous Region, China. An interview guide （semi-structured with open-ended questions） was developed to provide a qualitative examination of the quality of life of PLHA. Results Participants identified that ART affects physical health, including the experience of pain, side effects, and opportunistic infections. ART imposes lifestyle constraints such as reduced mobility due to drug procurement, and social restrictions due to the daily drug regimen. Participants discussed the psychological burden of taking drugs, and the fear of accidental transmission to others, or having their disease status known by others, as well as optimistic feelings about their future due to ART. ART poses a significant drain on individual＇s economic resources due to related medical costs, and inability to seek seasonal migrant labor due to reduced mobility. Conclusion While China＇s national free ART program improved the physical health of those surveyed, their social and economic needs were left unaddressed. To improve life outcomes for PLHA, and by extension, the wider Chinese population, quality of life measures should be included when evaluating the success of the ART program.
基金the Guangxi Medical and Health Project[Z20170126]the National Natural Science Foundation of China[Grant numbers 11971479,81502862,81460510,81360442,and 91546203]+2 种基金Guangxi Science and Technology Bureau[Grant number AB16380213]Guangxi Bagui Honor Scholarship,Ministry of Science and Technology of China[2018ZX10721102-006 and 2017ZX10201101]Guangxi Key Laboratory of AIDS Prevention Control and Translation,and Chinese State Key Laboratory of Infectious Disease Prevention and Control.
文摘Combination antiretroviral therapy(ART)reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication,enhancing immune recovery,and preventing the onset of opportunistic infections[1].In China,ART has rapidly been scaled up since the beginning of the National Free Antiretroviral Treatment Program(NFATP)in 2003[2].By the end of 2016,489,411 individuals diagnosed with HIV were receiving free antiretroviral treatment in China.China is firmly committed to reducing overall AIDS-related mortality and HIV incidence within the country.However,similar to other low-and middle-income countries,the NFATP is challenged by high mortality and attrition shortly after patients initiate ART[3].
