目的:探讨和血明目片联合雷珠单抗治疗视网膜静脉阻塞(RVO)伴黄斑水肿对患者黄斑形态学变化及预后随访。方法:选择启东市中医院2018年12月-2021年6月收治RVO伴黄斑水肿病患者128例(128只眼)为研究对象,按照随机数字表法将其分为试验组(6...目的:探讨和血明目片联合雷珠单抗治疗视网膜静脉阻塞(RVO)伴黄斑水肿对患者黄斑形态学变化及预后随访。方法:选择启东市中医院2018年12月-2021年6月收治RVO伴黄斑水肿病患者128例(128只眼)为研究对象,按照随机数字表法将其分为试验组(64只眼)和对照组(64只眼),每组64例。试验组采用和血明目片联合雷珠单抗治疗,对照组采用雷珠单抗治疗。对比两组视力疗效、最佳矫正视力变化、黄斑厚度变化、出血面积、视网膜渗漏变化及不良反应发生情况。结果:治疗后3个月,试验组视力提高率高于对照组(84.38% vs 73.44%)(P<0.05)。治疗后3个月,两组最佳矫正视力均高于治疗前,且试验组高于对照组,差异均有统计学意义(P<0.05)。治疗后3个月,两组黄斑厚度和出血灶面积均低于治疗前,且试验组均低于对照组,差异均有统计学意义(P<0.05)。试验组治疗后3个月渗漏面积总改善率高于对照组(89.06% vs 73.44%)(P<0.05)。两组治疗过程中均未出现任何不良反应情况。结论:RVO伴黄斑水肿患者选择和血明目片联合雷珠单抗治疗可提高患者视力,并且还能减轻黄斑水肿,改善视网膜渗漏面积,安全性高,值得临床大力推广及应用。展开更多
To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to it.First,the meta c...To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to it.First,the meta concept model of the C4ISR architecture is introduced.According to the meta concept model,we construct the executable meta models of the C4ISR architecture by extending the meta models of fUML.Then,we define the concrete syntax and executable activity algebra(EAA)semantics for executable models.The semantics functions are introduced to translating the syntax description of executable models into the item of EAA.To support the execution of models,we propose the executable rules which are the structural operational semantics of EAA.Finally,an area air defense of the C4ISR system is used to illustrate the feasibility of the approach.展开更多
The network diameter is an important characteristic parameter of a complex network. Calculation for a large-scale complex network’s diameter has been an important subject in the study of complex networks. If the netw...The network diameter is an important characteristic parameter of a complex network. Calculation for a large-scale complex network’s diameter has been an important subject in the study of complex networks. If the network diameter is calculated directly, the problem mainly exists in efficiency for searching and counting the shortest paths. If the network diameter is calculated indirectly by studying the statistical function about the relationship between the network diameter and parameters affecting the diameter, the problems not only exist in the efficiency of statistic, but also exist in the function which may be not applicable to all kinds of networks. An algorithm for the complex network diameter based on the k order distance matrix is proposed with a matrix multiplication approach, and a mathematical proof for the algorithm correctness is given as well. Furthermore, some relevant propositions and deductions for reducing the complexity of this algorithm are put forward. With a good theoretical basis and a simple calculation process, this algorithm can be used to calculate the diameter of a large-scale complex network with small-world effect more accurately and efficiently. Two cases about the advanced research projects agency(ARPA) network model and the Chinese airline network model are adopted to verify the effect of this algorithm.展开更多
文摘目的:探讨和血明目片联合雷珠单抗治疗视网膜静脉阻塞(RVO)伴黄斑水肿对患者黄斑形态学变化及预后随访。方法:选择启东市中医院2018年12月-2021年6月收治RVO伴黄斑水肿病患者128例(128只眼)为研究对象,按照随机数字表法将其分为试验组(64只眼)和对照组(64只眼),每组64例。试验组采用和血明目片联合雷珠单抗治疗,对照组采用雷珠单抗治疗。对比两组视力疗效、最佳矫正视力变化、黄斑厚度变化、出血面积、视网膜渗漏变化及不良反应发生情况。结果:治疗后3个月,试验组视力提高率高于对照组(84.38% vs 73.44%)(P<0.05)。治疗后3个月,两组最佳矫正视力均高于治疗前,且试验组高于对照组,差异均有统计学意义(P<0.05)。治疗后3个月,两组黄斑厚度和出血灶面积均低于治疗前,且试验组均低于对照组,差异均有统计学意义(P<0.05)。试验组治疗后3个月渗漏面积总改善率高于对照组(89.06% vs 73.44%)(P<0.05)。两组治疗过程中均未出现任何不良反应情况。结论:RVO伴黄斑水肿患者选择和血明目片联合雷珠单抗治疗可提高患者视力,并且还能减轻黄斑水肿,改善视网膜渗漏面积,安全性高,值得临床大力推广及应用。
文摘To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to it.First,the meta concept model of the C4ISR architecture is introduced.According to the meta concept model,we construct the executable meta models of the C4ISR architecture by extending the meta models of fUML.Then,we define the concrete syntax and executable activity algebra(EAA)semantics for executable models.The semantics functions are introduced to translating the syntax description of executable models into the item of EAA.To support the execution of models,we propose the executable rules which are the structural operational semantics of EAA.Finally,an area air defense of the C4ISR system is used to illustrate the feasibility of the approach.
基金supported by the National Natural Science Foundation of China(61273210)
文摘The network diameter is an important characteristic parameter of a complex network. Calculation for a large-scale complex network’s diameter has been an important subject in the study of complex networks. If the network diameter is calculated directly, the problem mainly exists in efficiency for searching and counting the shortest paths. If the network diameter is calculated indirectly by studying the statistical function about the relationship between the network diameter and parameters affecting the diameter, the problems not only exist in the efficiency of statistic, but also exist in the function which may be not applicable to all kinds of networks. An algorithm for the complex network diameter based on the k order distance matrix is proposed with a matrix multiplication approach, and a mathematical proof for the algorithm correctness is given as well. Furthermore, some relevant propositions and deductions for reducing the complexity of this algorithm are put forward. With a good theoretical basis and a simple calculation process, this algorithm can be used to calculate the diameter of a large-scale complex network with small-world effect more accurately and efficiently. Two cases about the advanced research projects agency(ARPA) network model and the Chinese airline network model are adopted to verify the effect of this algorithm.
